olaparib

collagen type XI alpha 2 chain ; Homo sapiens







115 Article(s)
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101 25025963 Phase I study of olaparib in combination with liposomal doxorubicin in patients with advanced solid tumours. 2014 Aug 12 1
102 25302077 Evolutionarily conserved genetic interactions with budding and fission yeast MutS identify orthologous relationships in mismatch repair-deficient cancer cells. 2014 1
103 23239809 Synergistic effect of olaparib with combination of cisplatin on PTEN-deficient lung cancer cells. 2013 Feb 1
104 23415752 BRCA1/2 mutation analysis in 41 ovarian cell lines reveals only one functionally deleterious BRCA1 mutation. 2013 Jun 1
105 23570906 Identification of miRNA modulators to PARP inhibitor response. 2013 Jun 1 1
106 23847380 Olaparib shows promise in multiple tumor types. 2013 Jul 1
107 23966292 EGFR-activating mutations correlate with a Fanconi anemia-like cellular phenotype that includes PARP inhibitor sensitivity. 2013 Oct 15 1
108 22562176 Inhibition of BRCT(BRCA1)-phosphoprotein interaction enhances the cytotoxic effect of olaparib in breast cancer cells: a proof of concept study for synthetic lethal therapeutic option. 2012 Jul 2
109 22915752 PI3K inhibition impairs BRCA1/2 expression and sensitizes BRCA-proficient triple-negative breast cancer to PARP inhibition. 2012 Nov 1
110 22933245 Synthetic lethality of PARP and NAMPT inhibition in triple-negative breast cancer cells. 2012 Oct 1
111 22987487 HER2 overexpression renders human breast cancers sensitive to PARP inhibition independently of any defect in homologous recombination DNA repair. 2012 Sep 15 1
112 21600381 Novel agents and future directions for refractory breast cancer. 2011 Jun 1
113 20922827 Targeted therapies: PARP inhibitor olaparib is safe and effective in patients with BRCA1 and BRCA2 mutations. 2010 Oct 1
114 20976249 Role for the mammalian Swi5-Sfr1 complex in DNA strand break repair through homologous recombination. 2010 Oct 14 1
115 19589159 Genomic profiling of breast tumours in relation to BRCA abnormalities and phenotypes. 2009 1