olaparib

poly(ADP-ribose) polymerase family member 12 ; Homo sapiens







14 Article(s)
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1 34954029 FDI-6 and olaparib synergistically inhibit the growth of pancreatic cancer by repressing BUB1, BRCA1 and CDC25A signaling pathways. 2022 Jan 2
2 35430559 Selective degradation of PARP2 by PROTACs via recruiting DCAF16 for triple-negative breast cancer. 2022 Jun 5 1
3 33976187 Androgen signaling uses a writer and a reader of ADP-ribosylation to regulate protein complex assembly. 2021 May 11 1
4 34158341 Radiopotentiation Profiling of Multiple Inhibitors of the DNA Damage Response for Early Clinical Development. 2021 Sep 1
5 30665945 The lysine-specific methyltransferase KMT2C/MLL3 regulates DNA repair components in cancer. 2019 Mar 1
6 31485633 DNA‑PKcs PARylation regulates DNA‑PK kinase activity in the DNA damage response. 2019 Oct 1
7 28655785 A Small-Molecule Inhibitor of WEE1, AZD1775, Synergizes with Olaparib by Impairing Homologous Recombination and Enhancing DNA Damage and Apoptosis in Acute Leukemia. 2017 Oct 1
8 29262611 PARP inhibition causes premature loss of cohesion in cancer cells. 2017 Nov 28 1
9 25302833 New therapeutic perspectives in CCDC6 deficient lung cancer cells. 2015 May 1 1
10 26180927 Long-term safety and anti-tumour activity of olaparib monotherapy after combination with carboplatin and paclitaxel in patients with advanced breast, ovarian or fallopian tube cancer. 2015 Jul 28 2
11 24240700 Genome-wide profiling of genetic synthetic lethality identifies CDK12 as a novel determinant of PARP1/2 inhibitor sensitivity. 2014 Jan 1 1
12 23934192 A high-throughput screen identifies PARP1/2 inhibitors as a potential therapy for ERCC1-deficient non-small cell lung cancer. 2013 Nov 21 2
13 24252502 ATM-depletion in breast cancer cells confers sensitivity to PARP inhibition. 2013 Nov 19 1
14 22194930 Checkpoint signaling, base excision repair, and PARP promote survival of colon cancer cells treated with 5-fluorodeoxyuridine but not 5-fluorouracil. 2011 2