tofacitinib

Janus kinase 3 ; Mus musculus







23 Article(s)
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PMID
Title
Pub. Year
#Total Relationships
1 34465864 PHF6 and JAK3 mutations cooperate to drive T-cell acute lymphoblastic leukemia progression. 2022 Feb 2
2 33814980 Mucosal Epithelial Jak Kinases in Health and Diseases. 2021 2
3 34274356 The JAK1/2 inhibitor baricitinib suppresses eosinophil effector function and restricts allergen-induced airway eosinophilia. 2021 Oct 2
4 32639993 Kinome capture sequencing of high-grade serous ovarian carcinoma reveals novel mutations in the JAK3 gene. 2020 2
5 30993508 Preformulation and Evaluation of Tofacitinib as a Therapeutic Treatment for Asthma. 2019 Apr 16 1
6 28852199 Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia. 2018 Mar 1
7 29986854 Partial trisomy 21 contributes to T-cell malignancies induced by JAK3-activating mutations in murine models. 2018 Jul 10 2
8 27745702 IL-4/IL-13-mediated polarization of renal macrophages/dendritic cells to an M2a phenotype is essential for recovery from acute kidney injury. 2017 Feb 1
9 28284718 Novel JAK3-Activating Mutations in Extranodal NK/T-Cell Lymphoma, Nasal Type. 2017 May 2
10 28884378 Efficacy of topical tofacitinib in promoting hair growth in non-scarring alopecia: possible mechanism via VEGF induction. 2017 Nov 2
11 27278657 JAK3-STAT pathway blocking benefits in experimental lupus nephritis. 2016 Jun 8 1
12 27732937 Tofacitinib induces G1 cell-cycle arrest and inhibits tumor growth in Epstein-Barr virus-associated T and natural killer cell lymphoma cells. 2016 Nov 22 1
13 29046866 Transforming Mutations of Jak3 (A573V and M511I) Show Differential Sensitivity to Selective Jak3 Inhibitors. 2016 2
14 26164790 Aggression behaviour induced by oral administration of the Janus-kinase inhibitor tofacitinib, but not oclacitinib, under stressful conditions. 2015 Oct 5 1
15 23689514 JAK3 deregulation by activating mutations confers invasive growth advantage in extranodal nasal-type natural killer cell lymphoma. 2014 Feb 1
16 25193870 JAK3 mutants transform hematopoietic cells through JAK1 activation, causing T-cell acute lymphoblastic leukemia in a mouse model. 2014 Nov 13 1
17 24565406 JAK3 inhibition: what potential for the future? 2013 Nov 20 1
18 22252297 Low dose CP-690,550 (tofacitinib), a pan-JAK inhibitor, accelerates the onset of experimental autoimmune encephalomyelitis by potentiating Th17 differentiation. 2012 Feb 10 2
19 21393628 Development of a high-throughput cell-based reporter assay for screening of JAK3 inhibitors. 2011 Apr 1
20 18094329 The specificity of JAK3 kinase inhibitors. 2008 Feb 15 1
21 18242596 The JAK-3 inhibitor CP-690550 is a potent anti-inflammatory agent in a murine model of pulmonary eosinophilia. 2008 Mar 17 2
22 14678034 The novel JAK-3 inhibitor CP-690550 is a potent immunosuppressive agent in various murine models. 2004 Jan 2
23 14593182 Prevention of organ allograft rejection by a specific Janus kinase 3 inhibitor. 2003 Oct 31 1