coomassie Brilliant Blue

purinergic receptor P2X, ligand-gated ion channel, 7 ; Mus musculus







53 Article(s)
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1 35254644 P2X7/P2X4 Receptors Mediate Proliferation and Migration of Retinal Microglia in Experimental Glaucoma in Mice. 2022 Mar 7 2
2 33463682 P2X7 receptor antagonism increases regulatory T cells and reduces clinical and histological graft-versus-host disease in a humanised mouse model. 2021 Feb 12 2
3 33734697 Depression Induced by Chronic Unpredictable Mild Stress Increases Susceptibility to Parkinson's Disease in Mice via Neuroinflammation Mediated by P2X7 Receptor. 2021 Apr 7 2
4 34638992 Novel P2X7 Antagonist Ameliorates the Early Phase of ALS Disease and Decreases Inflammation and Autophagy in SOD1-G93A Mouse Model. 2021 Sep 30 1
5 32170537 The P2X7 receptor antagonist JNJ-47965567 administered thrice weekly from disease onset does not alter progression of amyotrophic lateral sclerosis in SOD1G93A mice. 2020 Mar 1
6 32471386 Brilliant blue G, a P2X7 receptor antagonist, attenuates early phase of renal inflammation, interstitial fibrosis and is associated with renal cell proliferation in ureteral obstruction in rats. 2020 May 29 4
7 32566102 Inhibition of P2X7 Purinergic Receptor Ameliorates Cardiac Fibrosis by Suppressing NLRP3/IL-1β Pathway. 2020 2
8 33005242 Brilliant blue G attenuates neuro-inflammation via regulating MAPKs and NF-κB signaling pathways in lipopolysaccharide-induced BV2 microglia cells. 2020 Nov 2
9 30445307 Purinergic P2X7 receptor blockade mitigates alcohol-induced steatohepatitis and intestinal injury by regulating MEK1/2-ERK1/2 signaling and egr-1 activity. 2019 Jan 1
10 30528164 8-Hydroxy-2-(1H-1,2,3-triazol-1-yl)-1,4-naphtoquinone derivatives inhibited P2X7 Receptor-Induced dye uptake into murine Macrophages. 2019 Apr 15 1
11 30545568 Long-term treatment with the P2X7 receptor antagonist Brilliant Blue G reduces liver inflammation in a humanized mouse model of graft-versus-host disease. 2019 Feb 1
12 29572578 Crucial role of P2X7 receptor for effector T cell activation in experimental autoimmune uveitis. 2018 May 1
13 30015007 A P2X7 receptor antagonist reverses behavioural alterations, microglial activation and neuroendocrine dysregulation in an unpredictable chronic mild stress (UCMS) model of depression in mice. 2018 Nov 1
14 30063882 Brilliant Blue G protects against photoreceptor injury in a murine endotoxin-induced uveitis model. 2018 Dec 3
15 28244110 The P2X7 receptor links mechanical strain to cytokine IL-6 up-regulation and release in neurons and astrocytes. 2017 May 1
16 28265522 P2X7 antagonism using Brilliant Blue G reduces body weight loss and prolongs survival in female SOD1G93A amyotrophic lateral sclerosis mice. 2017 2
17 28344198 Radiosensitizing Effect of P2X7 Receptor Antagonist on Melanoma in Vitro and in Vivo. 2017 Jun 1 4
18 28597172 The P2X7 receptor is not essential for development of imiquimod-induced psoriasis-like inflammation in mice. 2017 Dec 2
19 28665482 The P2X7 receptor antagonist Brilliant Blue G reduces serum human interferon-γ in a humanized mouse model of graft-versus-host disease. 2017 Oct 5
20 28669743 Evidence that activation of P2X7R does not exacerbate neuronal death after optic nerve transection and focal cerebral ischemia in mice. 2017 Oct 3
21 28702712 Evaluation of the Anticonvulsant Effect of Brilliant Blue G, a Selective P2X7 Receptor Antagonist, in the iv PTZ-, Maximal Electroshock-, and 6 Hz-Induced Seizure Tests in Mice. 2017 Nov 2
22 28848393 The P2X7 Receptor Primes IL-1β and the NLRP3 Inflammasome in Astrocytes Exposed to Mechanical Strain. 2017 5
23 28930866 P2X7R Blockade Prevents NLRP3 Inflammasome Activation and Pancreatic Fibrosis in a Mouse Model of Chronic Pancreatitis. 2017 Nov/Dec 1
24 29070142 [Effect of BBG on Acute Graft-Versus-Host Disease in Mice after Allogeneic Hematopoietic Stem Cell Transplantation]. 2017 Oct 4
25 29084623 Alcohol intake in two different mouse drinking models after recovery from the lipopolysaccharide-induced sickness reaction. 2017 Dec 1
26 26349656 Mechanisms of NLRP3 inflammasome activation and its role in NSAID-induced enteropathy. 2016 May 1
27 27531364 The P2X7 Receptor Involved in gp120-Induced Cell Injury in BV2 Microglia. 2016 Oct 2
28 27544305 The impact of P2X7 receptor antagonist, brilliant blue G on graft-versus-host disease in mice after allogeneic hematopoietic stem cell transplantation. 2016 Dec 5
29 25937482 Blockage of P2X7 attenuates acute lung injury in mice by inhibiting NLRP3 inflammasome. 2015 Jul 2
30 26122280 Extracellular ATP enhances radiation-induced brain injury through microglial activation and paracrine signaling via P2X7 receptor. 2015 Nov 3
31 24493313 Role of P2X7 purinoceptors in neuroprotective mechanism of ischemic postconditioning in mice. 2014 May 1
32 24851118 Effects of Brilliant Blue G on Serum Tumor Necrosis Factor-α Levels and Depression-like Behavior in Mice after Lipopolysaccharide Administration. 2014 Apr 2
33 24885962 Effect of genetic deletion and pharmacological antagonism of P2X7 receptors in a mouse animal model of migraine. 2014 May 1 1
34 22243662 The absence of P2X7 receptors (P2rx7) on non-haematopoietic cells leads to selective alteration in mood-related behaviour with dysregulated gene expression and stress reactivity in mice. 2013 Feb 3
35 23308196 Dynamic increase in extracellular ATP accelerates photoreceptor cell apoptosis via ligation of P2RX7 in subretinal hemorrhage. 2013 1
36 23431238 P2X7 receptor activation induces reactive oxygen species formation and cell death in murine EOC13 microglia. 2013 1
37 23583883 Motor neuron dysfunction in a mouse model of ALS: gender-dependent effect of P2X7 antagonism. 2013 Sep 6 1
38 23727220 P2X7 receptors at adult neural progenitor cells of the mouse subventricular zone. 2013 Oct 1
39 23770338 P2X7 receptor activation regulates microglial cell death during oxygen-glucose deprivation. 2013 Oct 5
40 24022661 P2X7 blockade attenuates murine lupus nephritis by inhibiting activation of the NLRP3/ASC/caspase 1 pathway. 2013 Dec 2
41 24101734 Purinergic P2X7 receptors mediate cell death in mouse cerebellar astrocytes in culture. 2013 Dec 2
42 24312160 P2X7 receptor inhibition increases CNTF in the subventricular zone, but not neurogenesis or neuroprotection after stroke in adult mice. 2013 Oct 2
43 25206704 Brilliant blue G attenuates lipopolysaccharide-mediated microglial activation and inflammation. 2013 Mar 5 1
44 21794079 P2X7 purinoceptor alterations in dystrophic mdx mouse muscles: relationship to pathology and potential target for treatment. 2012 May 1
45 22733008 Defective T-lymphocyte migration to muscles in dystrophin-deficient mice. 2012 Aug 1
46 22815977 Activation of P2X7 promotes cerebral edema and neurological injury after traumatic brain injury in mice. 2012 3
47 21983632 Critical involvement of extracellular ATP acting on P2RX7 purinergic receptors in photoreceptor cell death. 2011 Dec 1
48 20645413 Contribution of P2X7 receptors to adenosine uptake by cultured mouse astrocytes. 2010 Nov 1 1
49 19385050 Functional decreases in P2X7 receptors are associated with retinoic acid-induced neuronal differentiation of Neuro-2a neuroblastoma cells. 2009 Jun 1
50 18037910 Cloning and pharmacological characterization of the guinea pig P2X7 receptor orthologue. 2008 Feb 1