Losartan

BCL2, apoptosis regulator ; Rattus norvegicus







13 Article(s)
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Pub. Year
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1 31957855 Losartan promotes myocardial apoptosis after acute myocardial infarction in rats through inhibiting Ang II-induced JAK/STAT pathway. 2020 Jan 2
2 30360036 Changes of Bax, Bcl-2, CCR-2, MCP-1, and TGF-β1 genes in the left ventricle of spontaneously hypertensive rat after losartan treatment. 2019 Mar 1
3 28844872 Losartan protects against cerebral ischemia/reperfusion-induced apoptosis through β-arrestin1-mediated phosphorylation of Akt. 2017 Nov 15 1
4 23875703 Involvement of the HIF-1α and Wnt/β-catenin pathways in the protective effects of losartan on fatty liver graft with ischaemia/reperfusion injury. 2014 Jan 1
5 22000973 Epigallocatechin gallate, the major component of polyphenols in green tea, inhibits telomere attrition mediated cardiomyocyte apoptosis in cardiac hypertrophy. 2013 Jan 20 1
6 23095236 The neuroprotective effect of losartan through inhibiting AT1/ASK1/MKK4/JNK3 pathway following cerebral I/R in rat hippocampal CA1 region. 2012 Dec 1
7 19298698 Synergism of simvastatin with losartan prevents angiotensin II-induced cardiomyocyte apoptosis in vitro. 2009 Apr 1
8 18630446 [Experimental study on losartan decreasing denervated skeletal muscle atrophy through reducing cell apoptosis]. 2008 May 1
9 17563572 Dose and time-dependent apoptotic effects by angiotensin II infusion on left ventricular cardiomyocytes. 2007 Jul 1
10 15502641 Angiotensin II mediates acinar cell apoptosis during the development of rat pancreatic fibrosis by AT1R. 2004 Nov 2
11 11403362 Postischemic apoptosis and functional recovery after angiotensin II type 1 receptor blockade in isolated working rat hearts. 2001 Jun 1
12 12845756 Study on the effects of losartan on cardiomyocyte apoptosis and gene expression after ischemia and reperfusion in vivo in rats. 2000 4
13 9719055 Overexpression of Bax protein and enhanced apoptosis in the left ventricle of spontaneously hypertensive rats: effects of AT1 blockade with losartan. 1998 Aug 1