Simvastatin

ras homolog family member A ; Rattus norvegicus







18 Article(s)
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1 31369604 Simvastatin causes pulmonary artery relaxation by blocking smooth muscle ROCK and calcium channels: Evidence for an endothelium-independent mechanism. 2019 1
2 31410004 Simvastatin pretreatment ameliorates t-PA-induced hemorrhage transformation and MMP-9/TIMP-1 imbalance in thromboembolic cerebral ischemic rats. 2019 2
3 28820400 Alteration in expressions of RhoA and Rho-kinases during pregnancy in rats: their roles in uterine contractions and onset of labour. 2017 Jun 1
4 27180285 Simvastatin inhibits protein isoprenylation in the brain. 2016 Aug 4 2
5 27216618 Simvastatin Attenuates Neuropathic Pain by Inhibiting the RhoA/LIMK/Cofilin Pathway. 2016 Sep 5
6 27306926 Simvastatin induces the apoptosis of normal vascular smooth muscle through the disruption of actin integrity via the impairment of RhoA/Rac-1 activity. 2016 Aug 30 3
7 27694473 Simvastatin prevents and reverses chronic pulmonary hypertension in newborn rats via pleiotropic inhibition of RhoA signaling. 2016 Nov 1 4
8 25612169 The rapid lipopolysaccharide-induced release of matrix metalloproteinases 9 is suppressed by simvastatin. 2015 Jul 1
9 24449418 Dysfunction of vascular smooth muscle and vascular remodeling by simvastatin. 2014 Apr 2
10 25275561 The effect of statin on epithelial-mesenchymal transition in peritoneal mesothelial cells. 2014 1
11 23900131 Simvastatin attenuates formalin-induced nociceptive behaviors by inhibiting microglial RhoA and p38 MAPK activation. 2013 Nov 4
12 21124329 Simvastatin prevents large blood pressure variability induced aggravation of cardiac hypertrophy in hypertensive rats by inhibiting RhoA/Ras-ERK pathways. 2011 Mar 1
13 21511701 Simvastatin enhances aquaporin-2 surface expression and urinary concentration in vasopressin-deficient Brattleboro rats through modulation of Rho GTPase. 2011 Aug 3
14 21790657 Erectile response to type 5 phosphodiesterase inhibitor could be preserved with the addition of simvastatin to conventional insulin treatment in rat model of diabetes. 2011 Oct 1
15 20629317 [Effects of simvastatin on proliferation and transition of phenotype in PDGF-BB-induced pulmonary artery smooth muscle cells]. 2010 May 1
16 19659652 Simvastatin attenuates experimental small airway remodelling in rats. 2009 Jul 2
17 19024099 Simvastatin attenuates lipopolysaccharide-induced airway mucus hypersecretion in rats. 2008 Sep 5 2
18 16698853 Simvastatin causes endothelial cell apoptosis and attenuates severe pulmonary hypertension. 2006 Oct 1