Simvastatin

cyclin dependent kinase 2 ; Homo sapiens







8 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 28833099 Simvastatin induces G1 arrest by up-regulating GSK3β and down-regulating CDK4/cyclin D1 and CDK2/cyclin E1 in human primary colorectal cancer cells. 2018 Jun 2
2 25738368 Molecular mechanism underlying the anticancer effect of simvastatin on MDA-MB-231 human breast cancer cells. 2015 Jul 1
3 20946258 Simvastatin inhibits glucose-stimulated vascular smooth muscle cell migration involving increased expression of RhoB and a block of Ras/Akt signal. 2012 Apr 1
4 21958871 Involvement of Chk1-Cdc25A-cyclin A/CDK2 pathway in simvastatin induced S-phase cell cycle arrest and apoptosis in multiple myeloma cells. 2011 Nov 30 4
5 20878096 Simvastatin inhibits cell growth and induces apoptosis and G0/G1 cell cycle arrest in hepatic cancer cells. 2010 Nov 1
6 17928568 HMG-CoA reductase inhibitor simvastatin inhibits cell cycle progression at the G1/S checkpoint in immortalized lymphocytes from Alzheimer's disease patients independently of cholesterol-lowering effects. 2008 Jan 2
7 18804536 Simvastatin inhibits cell cycle progression in glucose-stimulated proliferation of aortic vascular smooth muscle cells by up-regulating cyclin dependent kinase inhibitors and p53. 2008 Sep-Oct 2
8 16985065 Differential efficacy of 3-hydroxy-3-methylglutaryl CoA reductase inhibitors on the cell cycle of prostate cancer cells. 2006 Sep 2