| 1 |
22893598 | A novel approach to the discovery of small-molecule ligands of CDK2. | 2012 Sep 24 |
1 |
| 2 |
20368335 | Pro-apoptotic role of Cdc25A: activation of cyclin B1/Cdc2 by the Cdc25A C-terminal domain. | 2010 Jun 4 |
1 |
| 3 |
20808948 | Binding of protein kinase inhibitors to synapsin I inferred from pair-wise binding site similarity measurements. | 2010 Aug 16 |
1 |
| 4 |
16770740 | Staurosporine-induced growth inhibition of glioma cells is accompanied by altered expression of cyclins, CDKs and CDK inhibitors. | 2006 May |
3 |
| 5 |
12191604 | Structural studies with inhibitors of the cell cycle regulatory kinase cyclin-dependent protein kinase 2. | 2002 Feb-Mar |
2 |
| 6 |
11396181 | Complex regulation of CDK2 and G1 arrest during neuronal differentiation of human prostatic cancer TSU-Prl cells by staurosporine. | 2001 Mar-Apr |
3 |
| 7 |
11121462 | Protection of normal proliferating cells against chemotherapy by staurosporine-mediated, selective, and reversible G(1) arrest. | 2000 Dec 20 |
3 |
| 8 |
10698260 | Both low and high concentrations of staurosporine induce G1 arrest through down-regulation of cyclin E and cdk2 expression. | 1999 Dec |
2 |
| 9 |
9703866 | Treatment of human glioblastoma cells with the staurosporine derivative CGP 41251 inhibits CDC2 and CDK2 kinase activity and increases radiation sensitivity. | 1998 Jul-Aug |
1 |
| 10 |
9828096 | The cyclin-dependent kinase inhibitors olomoucine and roscovitine arrest human fibroblasts in G1 phase by specific inhibition of CDK2 kinase activity. | 1998 Nov 25 |
1 |
| 11 |
9334743 | Protein kinase inhibition by staurosporine revealed in details of the molecular interaction with CDK2. | 1997 Oct |
3 |
| 12 |
9438871 | Structures of staurosporine bound to CDK2 and cAPK--new tools for structure-based design of protein kinase inhibitors. | 1997 Dec 15 |
2 |
| 13 |
8626584 | Suppression of apoptosis by dominant negative mutants of cyclin-dependent protein kinases. | 1996 Apr 26 |
1 |
| 14 |
8650198 | G1 arrest and down-regulation of cyclin E/cyclin-dependent kinase 2 by the protein kinase inhibitor staurosporine are dependent on the retinoblastoma protein in the bladder carcinoma cell line 5637. | 1996 Jun 11 |
4 |
| 15 |
8838866 | Staurosporine resistance accompanies DNA tumor virus-induced immortalization and is independent of the expression and activities of ERK1, ERK2, cyclin A, cyclin-dependent kinase (cdk) 2, and cdk4. | 1996 Mar |
1 |
| 16 |
8891334 | Staurosporine-induced G1 arrest is associated with the induction and accumulation of cyclin-dependent kinase inhibitors. | 1996 Oct |
2 |
| 17 |
7954429 | The kinase inhibitor staurosporine induces G1 arrest at two points: effect on retinoblastoma protein phosphorylation and cyclin-dependent kinase 2 in normal and transformed cells. | 1994 Nov 15 |
1 |