Arsenic Trioxide

caspase 9 ; Homo sapiens







30 Article(s)
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1 28187727 Cryptotanshinone enhances the effect of Arsenic trioxide in treating liver cancer cell by inducing apoptosis through downregulating phosphorylated- STAT3 in vitro and in vivo. 2017 Feb 10 1
2 29164574 Mechanism of As2O3 induces apoptosis of glioma U87 cells. 2017 Nov 1
3 25258189 Endoplasmic reticulum stress contributes to arsenic trioxide-induced intrinsic apoptosis in human umbilical and bone marrow mesenchymal stem cells. 2016 Mar 1
4 25815518 Synergistic effects of valproic acid and arsenic trioxide on RPMI8226 cells in vitro and the possible underlying mechanisms. 2015 Jul 1
5 26692822 Arsenic trioxide reduces chemo-resistance to 5-fluorouracil and cisplatin in HBx-HepG2 cells via complex mechanisms. 2015 1
6 25130820 [Apoptosis-inducing effect of valproic acid combined with arsenic trioxide on RPMI 8226 cells and its mechanism]. 2014 Aug 1
7 25174355 E2F1 downregulation by arsenic trioxide in lung adenocarcinoma. 2014 Nov 1
8 23980369 [Homoharringtonine combined arsenic trioxide induced apoptosis in human multiple myeloma cell line RPMI 8226: an experimental research]. 2013 Jun 1
9 21826188 Synergistic Apoptosis-Inducing Antileukemic Effects of Arsenic Trioxide and Mucuna macrocarpa Stem Extract in Human Leukemic Cells via a Reactive Oxygen Species-Dependent Mechanism. 2012 1
10 23041229 2-Deoxy-D-glucose cooperates with arsenic trioxide to induce apoptosis in leukemia cells: involvement of IGF-1R-regulated Akt/mTOR, MEK/ERK and LKB-1/AMPK signaling pathways. 2012 Dec 15 1
11 21518486 [NB4 cell apoptosis induced by bortezomib combined with As(2)O(3) and its mechanism]. 2011 Apr 1
12 21655183 BIM-mediated AKT phosphorylation is a key modulator of arsenic trioxide-induced apoptosis in cisplatin-sensitive and -resistant ovarian cancer cells. 2011 1
13 21729541 [Apoptosis of KBM5R cell line with T315I point mutation induced by arsenic trioxide]. 2011 Jun 2
14 21846841 Epoxyeicosatrienoic acids attenuate reactive oxygen species level, mitochondrial dysfunction, caspase activation, and apoptosis in carcinoma cells treated with arsenic trioxide. 2011 Nov 1
15 20605902 Curcumin stimulates reactive oxygen species production and potentiates apoptosis induction by the antitumor drugs arsenic trioxide and lonidamine in human myeloid leukemia cell lines. 2010 Oct 1
16 18173754 P38 MAPK inhibition enhancing ATO-induced cytotoxicity against multiple myeloma cells. 2008 Jan 1
17 18566239 Arsenic trioxide decreases AKT protein in a caspase-dependent manner. 2008 Jun 1
18 18652763 Augmentation by carnosic acid of apoptosis in human leukaemia cells induced by arsenic trioxide via upregulation of the tumour suppressor PTEN. 2008 Jul-Aug 1
19 19771260 Arsenic trioxide induces apoptosis in human colorectal adenocarcinoma HT-29 cells through ROS. 2006 Feb 1
20 15674346 Arsenic trioxide triggers a regulated form of caspase-independent necrotic cell death via the mitochondrial death pathway. 2005 Mar 10 1
21 16007134 Arsenic trioxide induces regulated, death receptor-independent cell death through a Bcl-2-controlled pathway. 2005 Oct 27 1
22 16010437 Arsenic trioxide mediates intrinsic and extrinsic pathways of apoptosis and cell cycle arrest in acute megakaryocytic leukemia. 2005 Aug 1
23 12531793 Arsenic trioxide-induced apoptosis in myeloma cells: p53-dependent G1 or G2/M cell cycle arrest, activation of caspase-8 or caspase-9, and synergy with APO2/TRAIL. 2003 May 15 2
24 12851490 Arsenic trioxide selectively induces early and extensive apoptosis via the APO2/caspase-8 pathway engaging the mitochondrial pathway in myeloma cells with mutant p53. 2003 Jul-Aug 1
25 12883267 Arsenic trioxide induces apoptosis in pancreatic cancer cells via changes in cell cycle, caspase activation, and GADD expression. 2003 Aug 1
26 26680977 Effect of Arsenic Trioxide in TRAIL (Tumor Necrosis Factor-related Apoptosis Inducing Ligand)-Mediated Apoptosis in Multiple Myeloma Cell Lines. 2003 Dec 1
27 12023044 Enhancement of radiation response in human cervical cancer cells in vitro and in vivo by arsenic trioxide (As2O3). 2002 May 22 1
28 12492118 Arsenic trioxide inhibits growth of human multiple myeloma cells in the bone marrow microenvironment. 2002 Aug 1
29 26680881 Arsenic Trioxide Induces Apoptosis of HL-60 Cells via Activation of Intrinsic Caspase Protease with Mitochondrial Dysfunction. 2002 Aug 1
30 11172589 Potential role of caspase-3 and -9 in arsenic trioxide-mediated apoptosis in PCI-1 head and neck cancer cells. 2001 Feb 3