| 1 |
35159680 | Safety Profile of Rapamycin Perfluorocarbon Nanoparticles for Preventing Cisplatin-Induced Kidney Injury. | 2022 Jan 21 |
1 |
| 2 |
35523039 | Sirolimus therapy restores the PD-1+ICOS+Tfh:CD45RA-Foxp3high activated Tfr cell balance in primary Sjögren's syndrome. | 2022 Jul |
1 |
| 3 |
34084203 | Rapamycin attenuates gene expression of programmed cell death protein-ligand 1 and Foxp3 in the brain; a novel mechanism proposed for immunotherapy in the brain. | 2021 Apr |
1 |
| 4 |
31074719 | Sirolimus selectively increases circulating Treg cell numbers and restores the Th17/Treg balance in rheumatoid arthritis patients with low disease activity or in DAS28 remission who previously received conventional disease-modifying anti-rheumatic drugs. | 2020 Jan-Feb |
2 |
| 5 |
31874182 | Treatment with rapamycin can restore regulatory T-cell function in IPEX patients. | 2020 Apr |
10 |
| 6 |
32381646 | Low-Dose Interleukin-2 Combined With Rapamycin Led to an Expansion of CD4+CD25+FOXP3+ Regulatory T Cells and Prolonged Human Islet Allograft Survival in Humanized Mice. | 2020 Aug |
2 |
| 7 |
32535334 | Low expressions of PD-L1 and CTLA-4 by induced CD4+CD25+ Foxp3+ Tregs in patients with SLE and their correlation with the disease activity. | 2020 Sep |
1 |
| 8 |
33238127 | A Two-Step Process of Effector Programming Governs CD4+ T Cell Fate Determination Induced by Antigenic Activation in the Steady State. | 2020 Nov 24 |
1 |
| 9 |
33329581 | Enhanced Fatty Acid Synthesis Leads to Subset Imbalance and IFN-γ Overproduction in T Helper 1 Cells. | 2020 |
3 |
| 10 |
30597187 | Sirolimus vs mycophenolate moftile in Tacrolimus based therapy following induction with Antithymocyte globulin promotes regulatory T cell expansion and inhibits RORγt and T-bet expression in kidney transplantation. | 2019 Sep |
1 |
| 11 |
30710527 | Correction of Defective T-Regulatory Cells From Patients With Crohn's Disease by Ex Vivo Ligation of Retinoic Acid Receptor-α. | 2019 May |
1 |
| 12 |
31512504 | Comparing the Effects of the mTOR Inhibitors Azithromycin and Rapamycin on In Vitro Expanded Regulatory T Cells. | 2019 Dec |
3 |
| 13 |
29551338 | Sirolimus in patients with clinically active systemic lupus erythematosus resistant to, or intolerant of, conventional medications: a single-arm, open-label, phase 1/2 trial. | 2018 Mar 24 |
1 |
| 14 |
29619032 | An Autocrine TNFα-Tumor Necrosis Factor Receptor 2 Loop Promotes Epigenetic Effects Inducing Human Treg Stability In Vitro. | 2018 |
1 |
| 15 |
28097735 | Autoimmune enteropathy and hepatitis in pediatric heart transplant recipient. | 2017 Mar |
1 |
| 16 |
28104514 | Increased Foxp3+Helios+ Regulatory T Cells and Decreased Acute Graft-versus-Host Disease after Allogeneic Bone Marrow Transplantation in Patients Receiving Sirolimus and RGI-2001, an Activator of Invariant Natural Killer T Cells. | 2017 Apr |
1 |
| 17 |
26886923 | Comparative Analysis of Protocols to Induce Human CD4+Foxp3+ Regulatory T Cells by Combinations of IL-2, TGF-beta, Retinoic Acid, Rapamycin and Butyrate. | 2016 |
1 |
| 18 |
26921303 | Suppressor Properties of Human CD8(+)CD28(-) T Cells in Mixed Leukocyte Reaction are not Affected by CsA and RAPA. | 2016 Oct |
1 |
| 19 |
27258186 | The role of regulatory B cells (Bregs) in the Tregs-amplifying effect of Sirolimus. | 2016 Sep |
1 |
| 20 |
27778276 | Transcriptional modulation of regulatory T cell development by novel regulators NR4As. | 2016 Nov |
1 |
| 21 |
26238486 | mTOR Inhibition Per Se Induces Nuclear Localization of FOXP3 and Conversion of Invariant NKT (iNKT) Cells into Immunosuppressive Regulatory iNKT Cells. | 2015 Sep 1 |
1 |
| 22 |
24107844 | Rapamycin induces ILT3(high)ILT4(high) dendritic cells promoting a new immunoregulatory pathway. | 2014 Apr |
1 |
| 23 |
25326164 | Late-onset of immunodysregulation, polyendocrinopathy, enteropathy, x-linked syndrome (IPEX) with intractable diarrhea. | 2014 Oct 18 |
1 |
| 24 |
23223314 | Conversion to sirolimus in kidney transplant recipients with squamous cell cancer and changes in immune phenotype. | 2013 Feb |
1 |
| 25 |
23375289 | Comparison of regulatory T cells and FoxP3-positive T-cell subsets in the peripheral blood of renal transplant recipients with sirolimus versus cyclosporine: a preliminary study. | 2013 Jan-Feb |
1 |
| 26 |
23913957 | Mechanistic target of rapamycin activation triggers IL-4 production and necrotic death of double-negative T cells in patients with systemic lupus erythematosus. | 2013 Sep 1 |
1 |
| 27 |
23968562 | Rapamycin has suppressive and stimulatory effects on human plasmacytoid dendritic cell functions. | 2013 Dec |
3 |
| 28 |
24123683 | Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivo. | 2013 Nov 15 |
1 |
| 29 |
24252673 | [The therapeutic mechanisms of sirolimus treatment for ischemic-type biliary lesions after liver transplantation]. | 2013 Aug |
2 |
| 30 |
22089244 | Acquired Omenn-like syndrome, a novel posttransplant autoaggression syndrome reversed by rapamycin. | 2012 Jan |
1 |
| 31 |
21094689 | Adoptive transfer of CD4+CD25+ regulatory cells combined with low-dose sirolimus and anti-thymocyte globulin delays acute rejection of renal allografts in Cynomolgus monkeys. | 2011 May |
1 |
| 32 |
21253593 | Retinoic acid and rapamycin differentially affect and synergistically promote the ex vivo expansion of natural human T regulatory cells. | 2011 Jan 6 |
1 |
| 33 |
21627613 | [Changes of content of regulatory lymphocytes and concentration of soluble interleukine-2 receptor in blood of patients with ischemic heart disease after coronary artery angioplasty with implantation of stents with rapamycin covering]. | 2011 |
1 |
| 34 |
20421479 | Conversion of Th2 memory cells into Foxp3+ regulatory T cells suppressing Th2-mediated allergic asthma. | 2010 May 11 |
1 |
| 35 |
20626386 | Rapamycin-conditioned donor dendritic cells differentiate CD4CD25Foxp3 T cells in vitro with TGF-beta1 for islet transplantation. | 2010 Aug |
1 |
| 36 |
20844194 | Combined administration of a mutant TGF-beta1/Fc and rapamycin promotes induction of regulatory T cells and islet allograft tolerance. | 2010 Oct 15 |
1 |
| 37 |
19250527 | Activated mammalian target of rapamycin is associated with T regulatory cell insufficiency in nasal polyps. | 2009 Feb 27 |
1 |
| 38 |
19453998 | Monotherapy rapamycin allows an increase of CD4 CD25 FoxP3 T cells in renal recipients. | 2009 Sep |
1 |
| 39 |
18313267 | Combination of rapamycin and IL-2 increases de novo induction of human CD4(+)CD25(+)FOXP3(+) T cells. | 2008 Jun |
1 |
| 40 |
18424697 | Cutting edge: Foxp3-mediated induction of pim 2 allows human T regulatory cells to preferentially expand in rapamycin. | 2008 May 1 |
2 |
| 41 |
18481161 | Use of sirolimus in IPEX and IPEX-like children. | 2008 Sep |
6 |
| 42 |
18559659 | Rapamycin monotherapy in patients with type 1 diabetes modifies CD4+CD25+FOXP3+ regulatory T-cells. | 2008 Sep |
2 |
| 43 |
17182569 | Selective survival of naturally occurring human CD4+CD25+Foxp3+ regulatory T cells cultured with rapamycin. | 2007 Jan 1 |
1 |
| 44 |
17287424 | Regulatory T cells and T cell depletion: role of immunosuppressive drugs. | 2007 Mar |
1 |
| 45 |
17453966 | Rapamycin enriches for CD4(+) CD25(+) CD27(+) Foxp3(+) regulatory T cells in ex vivo-expanded CD25-enriched products from healthy donors and patients with multiple sclerosis. | 2007 |
2 |
| 46 |
18021968 | The influence of immuosuppressive therapy on the development of CD4+CD25+ T cells after renal transplantation. | 2007 Nov |
2 |
| 47 |
16517728 | Molecular mechanisms underlying FOXP3 induction in human T cells. | 2006 Mar 15 |
1 |
| 48 |
17142730 | Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients. | 2006 Dec 15 |
3 |
| 49 |
16126062 | Successful use of the new immune-suppressor sirolimus in IPEX (immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome). | 2005 Aug |
2 |