Heme

nitric oxide synthase 2 ; Homo sapiens







83 Article(s)
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51 11689556 Mechanistic studies with potent and selective inducible nitric-oxide synthase dimerization inhibitors. 2002 Jan 4 2
52 11926824 Control of nitric oxide synthase dimer assembly by a heme-NO-dependent mechanism. 2002 Apr 9 10
53 11463332 Nitric oxide synthases: structure, function and inhibition. 2001 Aug 1 2
54 11985981 Iron deficiency suppresses ileal nitric oxide synthase activity. 2001 Jul-Aug 1
55 10803847 Molecular and functional characterization of a fish inducible-type nitric oxide synthase. 2000 Apr 1
56 10846172 Aromatic residues and neighboring Arg414 in the (6R)-5,6,7, 8-tetrahydro-L-biopterin binding site of full-length neuronal nitric-oxide synthase are crucial in catalysis and heme reduction with NADPH. 2000 Aug 25 1
57 11076874 Inhibition of inducible nitric oxide synthase in the human intestinal epithelial cell line, DLD-1, by the inducers of heme oxygenase 1, bismuth salts, heme, and nitric oxide donors. 2000 Dec 6
58 9873034 Antifungal imidazoles block assembly of inducible NO synthase into an active dimer. 1999 Jan 8 1
59 10409685 Crystal structures of zinc-free and -bound heme domain of human inducible nitric-oxide synthase. Implications for dimer stability and comparison with endothelial nitric-oxide synthase. 1999 Jul 23 1
60 10455137 Geminate recombination of nitric oxide to endothelial nitric-oxide synthase and mechanistic implications. 1999 Aug 27 1
61 10480907 Crucial role of Lys(423) in the electron transfer of neuronal nitric-oxide synthase. 1999 Sep 17 1
62 9442050 The crucial roles of Asp-314 and Thr-315 in the catalytic activation of molecular oxygen by neuronal nitric-oxide synthase. A site-directed mutagenesis study. 1998 Jan 23 1
63 9488682 Electron transfer and catalytic activity of nitric oxide synthases. Chimeric constructs of the neuronal, inducible, and endothelial isoforms. 1998 Mar 6 1
64 9538001 Mechanism of inducible nitric oxide synthase inactivation by aminoguanidine and L-N6-(1-iminoethyl)lysine. 1998 Apr 7 5
65 9662510 The high-potential flavin and heme of nitric oxide synthase are not magnetically linked: implications for electron transfer. 1998 Jul 1
66 9668073 Domain swapping in inducible nitric-oxide synthase. Electron transfer occurs between flavin and heme groups located on adjacent subunits in the dimer. 1998 Jul 24 2
67 9721014 Nitric oxide synthases: catalytic function and progress towards selective inhibition. 1998 Jul 1
68 9109669 Interactions between substrate analogues and heme ligands in nitric oxide synthase. 1997 Apr 15 1
69 9173873 Cysteine-200 of human inducible nitric oxide synthase is essential for dimerization of haem domains and for binding of haem, nitroarginine and tetrahydrobiopterin. 1997 Apr 1 1
70 8621484 Conserved Glu318 at the cytochrome P450 1A2 distal site is crucial in the nitric oxide complex stability. 1996 Apr 12 1
71 8631749 Heme iron reduction and catalysis by a nitric oxide synthase heterodimer containing one reductase and two oxygenase domains. 1996 Mar 29 2
72 8643499 Complementation analysis of mutants of nitric oxide synthase reveals that the active site requires two hemes. 1996 May 14 1
73 8672462 Electron paramagnetic resonance spectroscopy of the heme domain of inducible nitric oxide synthase: binding of ligands at the arginine site induces changes in the heme ligation geometry. 1996 Jun 18 4
74 8753809 The natural product noformycin is an inhibitor of inducible-nitric oxide synthase. 1996 Aug 14 1
75 7499198 Characterization by electron paramagnetic resonance of the interactions of L-arginine and L-thiocitrulline with the heme cofactor region of nitric oxide synthase. 1995 Nov 17 1
76 7530045 Macrophage NO synthase: characterization of isolated oxygenase and reductase domains reveals a head-to-head subunit interaction. 1995 Jan 24 1
77 7544348 Identification of nitric oxide synthase as a thiolate-ligated heme protein using magnetic circular dichroism spectroscopy. Comparison with cytochrome P-450-CAM and chloroperoxidase. 1995 Aug 25 1
78 7547858 Reconstitution of the second step in NO synthesis using the isolated oxygenase and reductase domains of macrophage NO synthase. 1995 Sep 12 1
79 7519607 L-arginine and calmodulin regulation of the heme iron reactivity in neuronal nitric oxide synthase. 1994 Aug 12 1
80 7520872 Identification of imidazole as L-arginine-competitive inhibitor of porcine brain nitric oxide synthase. 1994 Aug 22 1
81 7524095 Heme coordination of NO in NO synthase. 1994 Oct 25 1
82 7686757 Oxidation of NG-hydroxy-L-arginine by nitric oxide synthase: evidence for the involvement of the heme in catalysis. 1993 Jun 30 1
83 7691806 Macrophage nitric oxide synthase subunits. Purification, characterization, and role of prosthetic groups and substrate in regulating their association into a dimeric enzyme. 1993 Oct 5 1