GW 3965

nuclear receptor subfamily 1, group H, member 3 ; Mus musculus







58 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35219337 LXR agonist improves peripheral neuropathy and modifies PNS immune cells in aged mice. 2022 Feb 26 2
2 35338002 Oridonin alleviates hyperbilirubinemia through activating LXRα-UGT1A1 axis. 2022 Apr 2
3 32170929 Sectm1a deficiency aggravates inflammation-triggered cardiac dysfunction through disruption of LXRα signalling in macrophages. 2021 Feb 22 4
4 34278533 Activation of the Hippocampal LXRβ Improves Sleep-Deprived Cognitive Impairment by Inhibiting Neuroinflammation. 2021 Oct 1
5 34335881 Role of liver-X-receptors in airway remodeling in mice with chronic allergic asthma. 2021 Sep 1
6 34564456 Combined LXR and RXR Agonist Therapy Increases ABCA1 Protein Expression and Enhances ApoAI-Mediated Cholesterol Efflux in Cultured Endothelial Cells. 2021 Sep 18 1
7 31980500 Differential Role of Liver X Receptor (LXR) α and LXRβ in the Regulation of UDP-Glucuronosyltransferase 1A1 in Humanized UGT1 Mice. 2020 Apr 1
8 32297184 Activation of LXRβ Signaling in the Amygdala Confers Anxiolytic Effects Through Rebalancing Excitatory and Inhibitory Neurotransmission upon Acute Stress. 2020 Jul 1
9 32329226 Complement Receptor Targeted Liposomes Encapsulating the Liver X Receptor Agonist GW3965 Accumulate in and Stabilize Atherosclerotic Plaques. 2020 May 4
10 32448508 LXR activation radiosensitizes non-small cell lung cancer by restricting myeloid-derived suppressor cells. 2020 Jul 23 1
11 33190106 Regulation of intestinal LDLR by the LXR-IDOL axis. 2020 Dec 2
12 30281809 LXRα Promotes Hepatosteatosis in Part Through Activation of MicroRNA-378 Transcription and Inhibition of Ppargc1β Expression. 2019 Apr 1
13 30964702 Liver X receptor-α activation enhances cholesterol secretion in lactating mammary epithelium. 2019 Jun 1 1
14 31066494 Peptide Amphiphile Supramolecular Nanostructures as a Targeted Therapy for Atherosclerosis. 2019 Jun 1
15 31104333 LXRα-mediated downregulation of EGFR suppress colorectal cancer cell proliferation. 2019 Oct 3
16 31856923 Ultra-early changes in vascular parameters from dynamic contrast enhanced MRI of breast cancer xenografts following systemic therapy with doxorubicin and liver X receptor agonist. 2019 Dec 19 2
17 29297151 Liver X Receptor Agonist GW3965 Regulates Synaptic Function upon Amyloid Beta Exposure in Hippocampal Neurons. 2018 Apr 3
18 29447944 Activation of liver X receptor β-enhancing neurogenesis ameliorates cognitive impairment induced by chronic cerebral hypoperfusion. 2018 Jun 1
19 28034754 LXR agonists promote the proliferation of neural progenitor cells through MEK-ERK pathway. 2017 Jan 29 2
20 28617705 Liver X Receptor α Is Involved in Counteracting Mechanical Allodynia by Inhibiting Neuroinflammation in the Spinal Dorsal Horn. 2017 Sep 1
21 28730752 Targeted Nanotherapeutics Encapsulating Liver X Receptor Agonist GW3965 Enhance Antiatherogenic Effects without Adverse Effects on Hepatic Lipid Metabolism in Ldlr-/- Mice. 2017 Oct 3
22 28741179 Activation of liver X receptor inhibits OCT2-mediated organic cation transport in renal proximal tubular cells. 2017 Nov 4
23 28926619 Liver X receptor activation promotes differentiation of regulatory T cells. 2017 2
24 27520356 Activation of Liver X Receptor Attenuates Oleic Acid-Induced Acute Respiratory Distress Syndrome. 2016 Oct 2
25 25156796 Nanoparticles containing a liver X receptor agonist inhibit inflammation and atherosclerosis. 2015 Jan 28 4
26 26163517 Combined Liver X Receptor/Peroxisome Proliferator-activated Receptor γ Agonist Treatment Reduces Amyloid β Levels and Improves Behavior in Amyloid Precursor Protein/Presenilin 1 Mice. 2015 Aug 28 1
27 26344074 Activation of LXRs using the synthetic agonist GW3965 represses the production of pro-inflammatory cytokines by murine mast cells. 2015 Sep 1
28 26720273 Role of Liver X Receptor in AD Pathophysiology. 2015 1
29 24163219 LXR driven induction of HDL-cholesterol is independent of intestinal cholesterol absorption and ABCA1 protein expression. 2014 Jan 1
30 24852699 Liver X Receptor activation delays chondrocyte hypertrophy during endochondral bone growth. 2014 Jul 1
31 24892989 Activation of liver X receptor enhances the proliferation and migration of endothelial progenitor cells and promotes vascular repair through PI3K/Akt/eNOS signaling pathway activation. 2014 Sep 1
32 25229406 Liver X receptor regulation of thyrotropin-releasing hormone transcription in mouse hypothalamus is dependent on thyroid status. 2014 1
33 25416469 Liver X receptor agonist treatment attenuates cardiac dysfunction in type 2 diabetic db/db mice. 2014 Nov 22 1
34 23159616 The liver X receptor promotes macrophage differentiation and suppresses osteoclast formation in mouse RAW264.7 promyelocytic leukemia cells exposed to bacterial lipopolysaccharide. 2013 Jan 4 1
35 23223141 Liver X receptor activation inhibits melanogenesis through the acceleration of ERK-mediated MITF degradation. 2013 Apr 1
36 23266787 Activation of Liver X receptors in the heart leads to accumulation of intracellular lipids and attenuation of ischemia-reperfusion injury. 2013 Jan 5
37 23349715 The liver X receptor agonist GW3965 improves recovery from mild repetitive traumatic brain injury in mice partly through apolipoprotein E. 2013 1
38 23419360 Liver X receptors inhibit proliferation of human colorectal cancer cells and growth of intestinal tumors in mice. 2013 Jun 1
39 23446231 LXR activation by GW3965 alters fat tissue distribution and adipose tissue inflammation in ob/ob female mice. 2013 May 2
40 23657115 Liver X receptor activation inhibits osteoclastogenesis by suppressing NF-κB activity and c-Fos induction and prevents inflammatory bone loss in mice. 2013 Jul 1
41 21889608 The LXR agonist GW3965 increases apoA-I protein levels in the central nervous system independent of ABCA1. 2012 Mar 2
42 23018104 Activation of liver X receptor attenuates endothelin-1 expression in vascular endothelial cells. 2012 Dec 2
43 23073827 Fasting-induced FGF21 is repressed by LXR activation via recruitment of an HDAC3 corepressor complex in mice. 2012 Dec 1
44 21030586 Liver X receptor (LXR) regulates human adipocyte lipolysis. 2011 Jan 7 1
45 21859686 Simultaneous activation of the liver X receptors (LXRα and LXRβ) drives murine collagen-induced arthritis disease pathology. 2011 Dec 2
46 20739291 ATP-binding cassette transporter A1 mediates the beneficial effects of the liver X receptor agonist GW3965 on object recognition memory and amyloid burden in amyloid precursor protein/presenilin 1 mice. 2010 Oct 29 2
47 19556420 Activation of liver X receptor regulates substrate oxidation in white adipocytes. 2009 Sep 1
48 19608643 Negative regulation of Hedgehog signaling by liver X receptors. 2009 Oct 1
49 18448072 PPARalpha gene expression is up-regulated by LXR and PXR activators in the small intestine. 2008 Jul 11 2
50 18549781 ApoE promotes the proteolytic degradation of Abeta. 2008 Jun 12 1