Ammonia

glutamate-ammonia ligase ; Homo sapiens







117 Article(s)
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Pub. Year
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1 34808107 Saul Brusilow: Understanding and treating diseases of ammonia toxicity. 2022 Jan 1 2
2 35044684 Glutamine synthetase evolutionary history revisited: Tracing back beyond the Last Universal Common Ancestor. 2022 Mar 2
3 35055927 Nitrogen Acquisition Strategies Mediated by Insect Symbionts: A Review of Their Mechanisms, Methodologies, and Case Studies. 2022 Jan 12 1
4 33927688 Astroglial Glutamine Synthetase and the Pathogenesis of Mesial Temporal Lobe Epilepsy. 2021 2
5 33962502 Glutamine synthetase as a central element in hepatic glutamine and ammonia metabolism: novel aspects. 2021 Aug 26 3
6 34220417 Glutamate Dehydrogenase Is Important for Ammonia Fixation and Amino Acid Homeostasis in Brain During Hyperammonemia. 2021 1
7 31986891 MicroRNA-140-5p suppresses invasion and proliferation of glioma cells by targeting glutamate-ammonia ligase (GLUL). 2020 Mar 1
8 32551588 Mechanism of Fully Reversible, pH-Sensitive Inhibition of Human Glutamine Synthetase by Tyrosine Nitration. 2020 Jul 14 1
9 32758585 Novel aspects of glutamine synthetase in ammonia homeostasis. 2020 Nov 4
10 33270177 Evaluation of [13N]ammonia positron emission tomography as a potential method for quantifying glutamine synthetase activity in the human brain. 2020 Dec 3 1
11 30671986 Ammonia and autophagy: An emerging relationship with implications for disorders with hyperammonemia. 2019 Nov 2
12 30765946 Role of Exercise in the Management of Hepatic Encephalopathy: Experience From Animal and Human Studies. 2019 Jan-Feb 1
13 31014748 Pathophysiology of hepatic encephalopathy and future treatment options. 2019 Apr - Jun 3
14 31067078 Glutamine synthetase in avian muscle contributes to a positive myogenic response to ammonia compared with mammalian muscle. 2019 Jul 1 1
15 31365859 Glutamine Synthetase Promotes Radiation Resistance via Facilitating Nucleotide Metabolism and Subsequent DNA Damage Repair. 2019 Jul 30 2
16 31817360 GLUL Ablation Can Confer Drug Resistance to Cancer Cells via a Malate-Aspartate Shuttle-Mediated Mechanism. 2019 Dec 5 1
17 29397952 Proteasome accessory factor A (PafA) transferase activity makes sense in the light of its homology with glutamine synthetase. 2018 Mar 2 1
18 29441491 In Silico Preliminary Association of Ammonia Metabolism Genes GLS, CPS1, and GLUL with Risk of Alzheimer's Disease, Major Depressive Disorder, and Type 2 Diabetes. 2018 Mar 1
19 29575012 High expression of glutamate-ammonia ligase is associated with unfavorable prognosis in patients with ovarian cancer. 2018 Jul 3
20 29651749 Medium-chain triglycerides supplement therapy with a low-carbohydrate formula can supply energy and enhance ammonia detoxification in the hepatocytes of patients with adult-onset type II citrullinemia. 2018 Sep 2
21 30076387 Structural Analysis of Glutamine Synthetase from Helicobacter pylori. 2018 Aug 3 1
22 30158707 Role of glutamine synthetase in angiogenesis beyond glutamine synthesis. 2018 Sep 2
23 28587465 Clarifying the Catalytic Mechanism of Human Glutamine Synthetase: A QM/MM Study. 2017 Jul 6 1
24 29383096 Hypoxia-inducible factor-1α promotes cell survival during ammonia stress response in ovarian cancer stem-like cells. 2017 Dec 29 2
25 26521983 Pathogenesis of hepatic encephalopathy in cirrhosis: the concept of synergism revisited. 2016 Dec 1
26 26836257 Molecular Mechanisms of Glutamine Synthetase Mutations that Lead to Clinically Relevant Pathologies. 2016 Feb 1
27 27023624 Central Role of Glutamate Metabolism in the Maintenance of Nitrogen Homeostasis in Normal and Hyperammonemic Brain. 2016 Mar 26 1
28 27367914 Recent advances in understanding renal ammonia metabolism and transport. 2016 Sep 3
29 27455801 [Function of zinc in liver disease]. 2016 Jul 1
30 27612942 β-Catenin signaling positively regulates glutamate uptake and metabolism in astrocytes. 2016 Sep 10 1
31 27651377 Current state of knowledge of hepatic encephalopathy (part I): newer treatment strategies for hyperammonemia in liver failure. 2016 Dec 1
32 27685475 Exploring the Catalytic Mechanism of Human Glutamine Synthetase by Computer Simulations. 2016 Oct 25 1
33 27885636 Glutamine Synthetase: Role in Neurological Disorders. 2016 1
34 31380466 Spectrophotometric Determination of Glutamine Synthetase Activity in Cultured Cells. 2016 Oct 5 1
35 25892675 Preliminary evaluation of an improved enzymatic assay method for measuring potassium concentrations in serum. 2015 Jun 15 1
36 26003724 Ammonia-induced oxidative damage in neurons is prevented by resveratrol and lipoic acid with participation of heme oxygenase 1. 2015 Jul 2
37 26102310 Multidrug resistance-associated protein 4 expression in ammonia-treated cultured rat astrocytes and cerebral cortex of cirrhotic patients with hepatic encephalopathy. 2015 Nov 1
38 26107238 Roles of Combined Glypican-3 and Glutamine Synthetase in Differential Diagnosis of Hepatocellular Lesions. 2015 1
39 26262937 Inhibition of glutamine synthetase in the central nucleus of the amygdala induces anhedonic behavior and recurrent seizures in a rat model of mesial temporal lobe epilepsy. 2015 Oct 1
40 26285131 Elevated baseline serum glutamate as a pharmacometabolomic biomarker for acamprosate treatment outcome in alcohol-dependent subjects. 2015 Aug 18 1
41 26321908 Reduced density of glutamine synthetase immunoreactive astrocytes in different cortical areas in major depression but not in bipolar I disorder. 2015 1
42 26599579 Influence of glutamine synthetase gene polymorphisms on the development of hyperammonemia during valproic acid-based therapy. 2015 Dec 1
43 25034052 Pathophysiology of brain dysfunction in hyperammonemic syndromes: The many faces of glutamine. 2014 Sep-Oct 1
44 25431095 [¹³N]Ammonia positron emission tomographic/computed tomographic imaging targeting glutamine synthetase expression in prostate cancer. 2014 1
45 23410662 Glutamine synthetase expression as a valuable marker of epilepsy and longer survival in newly diagnosed glioblastoma multiforme. 2013 May 2
46 23456516 Ornithine phenylacetate revisited. 2013 Jun 3
47 23628343 Clinical and biochemical aspects of primary and secondary hyperammonemic disorders. 2013 Aug 15 2
48 23724459 Expressional changes of carbamoyl phosphate synthetase and glutamine synthetase in the liver of rat with thioacetamide-induced cirrhosis. 2013 Jan 1
49 23791709 Regulation of astrocyte glutamine synthetase in epilepsy. 2013 Dec 1
50 23880158 Lipoic acid protects C6 cells against ammonia exposure through Na⁺-K⁺-Cl⁻ co-transporter and PKC pathway. 2013 Oct 1