| 1 |
35135596 | Up-regulation of MTHFD2 is associated with clinicopathological characteristics and poor survival in ovarian cancer, possibly by regulating MOB1A signaling. | 2022 Feb 8 |
1 |
| 2 |
35228749 | Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress. | 2022 Feb |
1 |
| 3 |
35349697 | Deacetylation of MTHFD2 by SIRT4 senses stress signal to inhibit cancer cell growth by remodeling folate metabolism. | 2022 Mar 29 |
5 |
| 4 |
33782411 | The folate cycle enzyme MTHFD2 induces cancer immune evasion through PD-L1 up-regulation. | 2021 Mar 29 |
4 |
| 5 |
34007312 | MTHFD2 facilitates breast cancer cell proliferation via the AKT signaling pathway. | 2021 Jul |
1 |
| 6 |
34244426 | p53 deficiency induces MTHFD2 transcription to promote cell proliferation and restrain DNA damage. | 2021 Jul 13 |
1 |
| 7 |
34421310 | Expression and Prognostic Value Identification of Methylenetetrahydrofolate Dehydrogenase 2 (MTHFD2) in Brain Low-Grade Glioma. | 2021 |
2 |
| 8 |
32088725 | High Expression of Methylenetetrahydrofolate Dehydrogenase 2 (MTHFD2) in Esophageal Squamous Cell Carcinoma and its Clinical Prognostic Significance. | 2020 Feb 23 |
1 |
| 9 |
32811824 | Cisplatin inhibits SIRT3-deacetylation MTHFD2 to disturb cellular redox balance in colorectal cancer cell. | 2020 Aug 6 |
1 |
| 10 |
32880830 | Detection and characterisation of novel alternative splicing variants of the mitochondrial folate enzyme MTHFD2. | 2020 Sep |
3 |
| 11 |
33168819 | MiR-22, regulated by MeCP2, suppresses gastric cancer cell proliferation by inducing a deficiency in endogenous S-adenosylmethionine. | 2020 Nov 10 |
1 |
| 12 |
33262939 | MTHFD2 Blockade Enhances the Efficacy of β-Lapachone Chemotherapy With Ionizing Radiation in Head and Neck Squamous Cell Cancer. | 2020 |
1 |
| 13 |
30532069 | Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2. | 2019 Apr |
2 |
| 14 |
30906627 | MicroRNA-940 inhibits glioma progression by blocking mitochondrial folate metabolism through targeting of MTHFD2. | 2019 |
2 |
| 15 |
31209892 | MicroRNA-33a-5p suppresses colorectal cancer cell growth by inhibiting MTHFD2. | 2019 Oct |
2 |
| 16 |
31496738 | The effect of MTHFD2 on the proliferation and migration of colorectal cancer cell lines. | 2019 |
1 |
| 17 |
31624245 | Combinatorial targeting of MTHFD2 and PAICS in purine synthesis as a novel therapeutic strategy. | 2019 Oct 17 |
1 |
| 18 |
28259896 | The one-carbon metabolism pathway highlights therapeutic targets for gastrointestinal cancer (Review). | 2017 Apr |
1 |
| 19 |
29225823 | Human mitochondrial MTHFD2 is a dual redox cofactor-specific methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase. | 2017 |
1 |
| 20 |
27257051 | Methylenetetrahydrofolate dehydrogenase 2 overexpression is associated with tumor aggressiveness and poor prognosis in hepatocellular carcinoma. | 2016 Aug |
2 |
| 21 |
27315223 | Suppression of MTHFD2 in MCF-7 Breast Cancer Cells Increases Glycolysis, Dependency on Exogenous Glycine, and Sensitivity to Folate Depletion. | 2016 Aug 5 |
2 |
| 22 |
26461067 | The folate-coupled enzyme MTHFD2 is a nuclear protein and promotes cell proliferation. | 2015 Oct 13 |
1 |