| 1 |
32660255 | Cdk5-Mediated Phosphorylation of Sirt1 Contributes to Podocyte Mitochondrial Dysfunction in Diabetic Nephropathy. | 2021 Jan 20 |
1 |
| 2 |
33931002 | Exploring multi-target inhibitors using in silico approach targeting cell cycle dysregulator-CDK proteins. | 2021 Apr 30 |
1 |
| 3 |
34182065 | Pharmacological relevance of CDK inhibitors in Alzheimer's disease. | 2021 Sep |
1 |
| 4 |
32974274 | Identification of Quinazolinone Analogs Targeting CDK5 Kinase Activity and Glioblastoma Cell Proliferation. | 2020 |
3 |
| 5 |
31073393 | Computational Simulations Identified Two Candidate Inhibitors of Cdk5/p25 to Abrogate Tau-associated Neurological Disorders. | 2019 |
3 |
| 6 |
31137734 | Computational Simulations Identify Pyrrolidine-2,3-Dione Derivatives as Novel Inhibitors of Cdk5/p25 Complex to Attenuate Alzheimer's Pathology. | 2019 May 24 |
1 |
| 7 |
31163256 | Myricetin prevents thapsigargin-induced CDK5-P66Shc signalosome mediated pancreatic β-cell dysfunction. | 2019 Sep |
1 |
| 8 |
30079618 | Amino acid sequence conservation of the algesic fragment of myelin basic protein is required for its interaction with CDK5 and function in pain. | 2018 Sep |
1 |
| 9 |
28868329 | Active Cdk5 Immunoprecipitation and Kinase Assay. | 2017 Jul 5 |
1 |
| 10 |
29856575 | [Progress in the study of new cancer target Cdk5 and its inhibitors]. | 2016 Feb |
1 |
| 11 |
24704205 | Acetylation of cyclin-dependent kinase 5 is mediated by GCN5. | 2014 Apr 25 |
2 |
| 12 |
24983862 | Investigation of the flexibility of protein kinases implicated in the pathology of Alzheimer's disease. | 2014 Jun 30 |
2 |
| 13 |
24998602 | Synthesis and biological evaluation of tetrahydro[1,4]diazepino[1,2-a]indol-1-ones as cyclin-dependent kinase inhibitors. | 2014 Aug 18 |
1 |
| 14 |
25438765 | Discovery of thienoquinolone derivatives as selective and ATP non-competitive CDK5/p25 inhibitors by structure-based virtual screening. | 2014 Nov 15 |
2 |
| 15 |
27481520 | Binding Mechanism of Inhibitors to CDK5/p25 Complex: Free Energy Calculation and Ranking Aggregation Analysis. | 2013 Mar |
2 |
| 16 |
21641213 | Novel purine-based fluoroaryl-1,2,3-triazoles as neuroprotecting agents: synthesis, neuronal cell culture investigations, and CDK5 docking studies. | 2011 Jul 1 |
1 |
| 17 |
21681969 | An in silico approach for the discovery of CDK5/p25 interaction inhibitors. | 2011 Jul |
2 |
| 18 |
20491486 | Kinetic mechanistic studies of Cdk5/p25-catalyzed H1P phosphorylation: metal effect and solvent kinetic isotope effect. | 2010 Jun 15 |
2 |
| 19 |
18636751 | Kinetic studies of Cdk5/p25 kinase: phosphorylation of tau and complex inhibition by two prototype inhibitors. | 2008 Aug 12 |
1 |
| 20 |
18220519 | New approaches to the discovery of cdk5 inhibitors. | 2007 Dec |
2 |
| 21 |
14761195 | Structural basis for the synthesis of indirubins as potent and selective inhibitors of glycogen synthase kinase-3 and cyclin-dependent kinases. | 2004 Feb 12 |
1 |
| 22 |
12112670 | Identification of the N-terminal functional domains of Cdk5 by molecular truncation and computer modeling. | 2002 Aug 15 |
3 |
| 23 |
12372407 | Molecular model of cyclin-dependent kinase 5 complexed with roscovitine. | 2002 Oct 11 |
1 |
| 24 |
11604388 | The cyclin-dependent kinases cdk2 and cdk5 act by a random, anticooperative kinetic mechanism. | 2001 Dec 21 |
1 |
| 25 |
10998059 | Paullones are potent inhibitors of glycogen synthase kinase-3beta and cyclin-dependent kinase 5/p25. | 2000 Oct |
1 |
| 26 |
11054815 | Phosphorylation of human tau protein by microtubule-associated kinases: GSK3beta and cdk5 are key participants. | 2000 Nov 1 |
1 |
| 27 |
10362524 | A model of the complex between cyclin-dependent kinase 5 and the activation domain of neuronal Cdk5 activator. | 1999 Jun 7 |
2 |
| 28 |
7592534 | Evidence for cdk5 as a major activity phosphorylating tau protein in porcine brain extract. | 1995 Apr |
2 |