Threonine

cyclin dependent kinase 5 ; Homo sapiens







40 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 28809765 Cyclin-dependent kinase 5 modulates the P2X2a receptor channel gating through phosphorylation of C-terminal threonine 372. 2017 Nov 1
2 26823173 Activation of the cAMP/protein kinase A signalling pathway by coronin 1 is regulated by cyclin-dependent kinase 5 activity. 2016 Jan 1
3 27735944 CDK5 functions as a tumor promoter in human colorectal cancer via modulating the ERK5-AP-1 axis. 2016 Oct 13 2
4 25355946 Effects of kinesin-5 inhibition on dendritic architecture and microtubule organization. 2015 Jan 1 1
5 25760044 Mechanisms of HIV-1 Tat neurotoxicity via CDK5 translocation and hyper-activation: role in HIV-associated neurocognitive disorders. 2015 2
6 25909891 Astrocyte NMDA receptors' activity sustains neuronal survival through a Cdk5-Nrf2 pathway. 2015 Nov 2
7 26376215 Phosphorylation of TRPV1 by cyclin-dependent kinase 5 promotes TRPV1 surface localization, leading to inflammatory thermal hyperalgesia. 2015 Nov 3
8 25076872 Physiological and pathological phosphorylation of tau by Cdk5. 2014 2
9 23362255 Isomerase Pin1 stimulates dephosphorylation of tau protein at cyclin-dependent kinase (Cdk5)-dependent Alzheimer phosphorylation sites. 2013 Mar 15 1
10 24235147 Cyclin-dependent kinase 5 (Cdk5) regulates the function of CLOCK protein by direct phosphorylation. 2013 Dec 27 2
11 22820052 Chronic hyperdopaminergic activity of schizophrenia is associated with increased ΔFosB levels and cdk-5 signaling in the nucleus accumbens. 2012 Oct 11 4
12 21056617 Hsp90 regulates tau pathology through co-chaperone complexes in Alzheimer's disease. 2011 Jan 1
13 21144757 Design, synthesis, and testing of an 6-O-linked series of benzimidazole based inhibitors of CDK5/p25. 2011 Jan 1 2
14 21209322 High NaCl-induced activation of CDK5 increases phosphorylation of the osmoprotective transcription factor TonEBP/OREBP at threonine 135, which contributes to its rapid nuclear localization. 2011 Mar 1 1
15 20457142 Okadaic acid induces tau phosphorylation in SH-SY5Y cells in an estrogen-preventable manner. 2010 Jul 23 1
16 20473298 The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death. 2010 Jun 1
17 20717630 [Roles of cyclin-dependent kinase 5 in central nervous system development and neurodegenerative diseases]. 2010 Aug 25 1
18 19136008 M phase-specific phosphorylation of histone H1.5 at threonine 10 by GSK-3. 2009 Feb 20 1
19 18818692 Cdk5 phosphorylates Cdh1 and modulates cyclin B1 stability in excitotoxicity. 2008 Oct 22 2
20 18948252 CDK5-dependent phosphorylation of the Rho family GTPase TC10(alpha) regulates insulin-stimulated GLUT4 translocation. 2008 Dec 19 3
21 17220300 Regulation of s6 kinase 1 activation by phosphorylation at ser-411. 2007 Mar 9 2
22 17301223 Protein kinase A activates protein phosphatase 2A by phosphorylation of the B56delta subunit. 2007 Feb 20 1
23 17693641 Phosphorylation blocks the activity of tubulin polymerization-promoting protein (TPPP): identification of sites targeted by different kinases. 2007 Oct 5 1
24 16407256 Different mechanisms of CDK5 and CDK2 activation as revealed by CDK5/p25 and CDK2/cyclin A dynamics. 2006 Mar 17 1
25 17121546 Identifying novel substrates for mouse Cdk5 kinase using the yeast Saccharomyces cerevisiae. 2006 Dec 1
26 15483118 Alpha2-chimaerin, cyclin-dependent Kinase 5/p35, and its target collapsin response mediator protein-2 are essential components in semaphorin 3A-induced growth-cone collapse. 2004 Oct 13 1
27 12832492 Cdk5 regulates the organization of Nestin and its association with p35. 2003 Jul 4
28 12056836 Cyclin-dependent kinase-5/p35 phosphorylates Presenilin 1 to regulate carboxy-terminal fragment stability. 2002 May 2
29 12071639 Colocalization and fluorescence resonance energy transfer between cdk5 and AT8 suggests a close association in pre-neurofibrillary tangles and neurofibrillary tangles. 2002 Jun 1
30 12226093 Truncation of CDK5 activator p35 induces intensive phosphorylation of Ser202/Thr205 of human tau. 2002 Nov 15 3
31 12387894 Involvement of aberrant glycosylation in phosphorylation of tau by cdk5 and GSK-3beta. 2002 Oct 23 7
32 11013232 Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors? 2001 Jan 5 1
33 11181841 Characterization of the in vitro phosphorylation of human tau by tau protein kinase II (cdk5/p20) using mass spectrometry. 2001 Feb 4
34 11604394 Phosphorylation of Pak1 by the p35/Cdk5 kinase affects neuronal morphology. 2001 Dec 28 1
35 10936190 Neuron-specific phosphorylation of Alzheimer's beta-amyloid precursor protein by cyclin-dependent kinase 5. 2000 Sep 2
36 11050161 Amplification of dopaminergic signaling by a positive feedback loop. 2000 Nov 7 2
37 10092646 Identification of substrate binding site of cyclin-dependent kinase 5. 1999 Apr 2 2
38 10366442 Cyclin-dependent kinase 5 activity enhances monocytic phenotype and cell cycle traverse in 1,25-dihydroxyvitamin D3-treated HL60 cells. 1999 Jun 15 1
39 10413323 Elevated neuronal Cdc2-like kinase activity in the Alzheimer disease brain. 1999 May 1
40 9735171 Phosphorylation of tau at both Thr 231 and Ser 262 is required for maximal inhibition of its binding to microtubules. 1998 Sep 15 1