purine

cyclin dependent kinase 5 ; Homo sapiens







7 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 30023695 A Simple Isomerization of the Purine Scaffold of a Kinase Inhibitor, Roscovitine, Affords a Four- to Seven-Fold Enhancement of Its Affinity for Four CDKs. Could This Be Traced Back to Conjugation-Induced Stiffenings/Loosenings of Rotational Barriers? 2017 Jul 31 2
2 26207228 Roscovitine in cancer and other diseases. 2015 Jun 1
3 21641213 Novel purine-based fluoroaryl-1,2,3-triazoles as neuroprotecting agents: synthesis, neuronal cell culture investigations, and CDK5 docking studies. 2011 Jul 1 1
4 16407256 Different mechanisms of CDK5 and CDK2 activation as revealed by CDK5/p25 and CDK2/cyclin A dynamics. 2006 Mar 17 1
5 14990704 Roscovitine, a cyclin-dependent kinase inhibitor, prevents replication of varicella-zoster virus. 2004 Mar 1
6 15308730 Roscovitine inhibits activation of promoters in herpes simplex virus type 1 genomes independently of promoter-specific factors. 2004 Sep 1
7 10465404 Synthesis and in vitro evaluation of novel 2,6,9-trisubstituted purines acting as cyclin-dependent kinase inhibitors. 1999 Jul 1