Simvastatin

matrix metallopeptidase 9 ; Homo sapiens







39 Article(s)
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1 34680049 HMG-CoA Reductase Inhibitor, Simvastatin Is Effective in Decreasing Degree of Myocarditis by Inhibiting Metalloproteinases Activation. 2021 Sep 28 2
2 32173476 Different Drugs Effect on Mesenchymal Stem Cells Isolated From Abdominal Aortic Aneurysm. 2020 Aug 3
3 32421147 Statins Suppress TGF-β2-Mediated MMP-2 and MMP-9 Expression and Activation Through RhoA/ROCK Inhibition in Astrocytes of the Human Optic Nerve Head. 2020 May 11 1
4 33250768 Simvastatin Suppresses Human Breast Cancer Cell Invasion by Decreasing the Expression of Pituitary Tumor-Transforming Gene 1. 2020 1
5 31260663 Effects of simvastatin on matrix metalloproteinase regulation in IL-1β-induced SW1353 cells. 2019 Sep 1 1
6 28390432 Impact of matrix metalloproteinase 9 rs3918242 genetic variant on lipid-lowering efficacy of simvastatin therapy in Chinese patients with coronary heart disease. 2017 Apr 8 3
7 26988924 Statin intake is associated with MMP-1 level in gingival crevicular fluid of patients with periodontitis. 2016 Jul 1
8 25704622 The Effect of Simvastatin on Infection-Induced Inflammatory Response of Human Fetal Membranes. 2015 Jul 1
9 25800096 The Influence of Simvastatin on NGAL, Matrix Metalloproteinases and Their Tissue Inhibitors in Human Intraluminal Thrombus and Abdominal Aortic Aneurysm Tissue. 2015 May 2
10 25993292 Inhibitory effect of statins on inflammation-related pathways in human abdominal aortic aneurysm tissue. 2015 May 18 2
11 24233024 Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene products. 2014 Mar 2
12 24506800 Low intravitreal angiopoietin-2 and VEGF levels in vitrectomized diabetic patients with simvastatin treatment. 2014 Nov 1
13 24684779 Synergistic anti-inflammatory effect: simvastatin and pioglitazone reduce inflammatory markers of plasma and epicardial adipose tissue of coronary patients with metabolic syndrome. 2014 Mar 31 1
14 25316568 Simvastatin induces NFκB/p65 down-regulation and JNK1/c-Jun/ATF-2 activation, leading to matrix metalloproteinase-9 (MMP-9) but not MMP-2 down-regulation in human leukemia cells. 2014 Dec 15 7
15 25432084 Effects of simvastatin on cell viability and proinflammatory pathways in lung adenocarcinoma cells exposed to hydrogen peroxide. 2014 Nov 29 1
16 23913656 Simvastatin therapy decreases MMP-9 levels in obese women. 2013 Oct 4
17 23924855 Simvastatin inhibits proliferation and induces apoptosis in human lung cancer cells. 2013 2
18 20946258 Simvastatin inhibits glucose-stimulated vascular smooth muscle cell migration involving increased expression of RhoB and a block of Ras/Akt signal. 2012 Apr 1
19 21448567 Effects of statins on matrix metalloproteinases and their endogenous inhibitors in human endothelial cells. 2011 Jun 2
20 19299917 Simvastatin inhibits induction of matrix metalloproteinase-9 in rat alveolar macrophages exposed to cigarette smoke extract. 2009 Apr 30 2
21 19589242 Simvastatin reduces OX40 and OX40 ligand expression in human peripheral blood mononuclear cells and in patients with atherosclerotic cerebral infarction. 2009 May-Jun 1
22 18326912 [Quantitative ultrasonic integrated backscatter of the intima-media complex, serum level of matrix metalloprotease-9 and simvastatin in hyperlipemia patients]. 2008 Feb 3
23 18625914 Simvastatin suppresses LPS-induced MMP-1 expression in U937 mononuclear cells by inhibiting protein isoprenylation-mediated ERK activation. 2008 Oct 1
24 17560598 Simvastatin inhibits TNFalpha-induced invasion of human cardiac myofibroblasts via both MMP-9-dependent and -independent mechanisms. 2007 Aug 3
25 17574455 Simvastatin attenuates the activity of matrix metalloprotease-9 in aneurysmal aortic tissue. 2007 Sep 1
26 16386257 Role of annexin II in estrogen-induced macrophage matrix metalloproteinase-9 activity: the modulating effect of statins. 2006 Nov 4
27 16741180 Reduction of tissue plasminogen activator-induced matrix metalloproteinase-9 by simvastatin in astrocytes. 2006 Jul 2
28 17184595 Simvastatin could prevent increase of the serum MMP-9/TIMP-1 ratio in acute ischaemic stroke. 2006 3
29 15728660 Simvastatin inhibits MMP-9 secretion from human saphenous vein smooth muscle cells by inhibiting the RhoA/ROCK pathway and reducing MMP-9 mRNA levels. 2005 May 6
30 16465063 HMG-CoA reductase inhibitors reduce matrix metalloproteinase-9 activity in human varicose veins. 2005 Nov-Dec 3
31 15107580 Simvastatin, an HMG-CoA reductase inhibitor, reduced the expression of matrix metalloproteinase-9 (Gelatinase B) in osteoblastic cells and HT1080 fibrosarcoma cells. 2004 Apr 4
32 15210533 Different effects of simvastatin and interferon beta on the proteolytic activity of matrix metalloproteinases. 2004 Jun 2
33 15458690 Comparative effects of statin and fibrate on nitric oxide bioactivity and matrix metalloproteinase in hyperlipidemia. 2004 Nov 1
34 15537504 Tumor necrosis factor alpha induces human atrial myofibroblast proliferation, invasion and MMP-9 secretion: inhibition by simvastatin. 2004 Dec 1 3
35 15706857 [Effects of Astragalus and saponins of Panax notoginseng on MMP-9 in patients with type 2 diabetic macroangiopathy]. 2004 Mar 1
36 12659988 Effects of statin on plaque stability and thrombogenicity in hypercholesterolemic patients with coronary artery disease. 2003 Mar 2
37 12023838 Statins for the prevention of vein graft stenosis: a role for inhibition of matrix metalloproteinase-9. 2002 Apr 1
38 12096273 Simvastatin inhibits human saphenous vein neointima formation via inhibition of smooth muscle cell proliferation and migration. 2002 Jul 1
39 11428539 Non-lipid effects of statin on hypercholesterolemic patients established to have coronary artery disease who remained hypercholesterolemic while eating a step-II diet. 2001 Jun 3