3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole

hypoxia inducible factor 1 subunit alpha ; Homo sapiens







26 Article(s)
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1 34457047 Effects of hypoxia on DNA hydroxymethylase Tet methylcytosine dioxygenase 2 in a KG-1 human acute myeloid leukemia cell line and its mechanism. 2021 Oct 1
2 34623134 Codelivery of High-Molecular-Weight Poly-porphyrins and HIF-1α Inhibitors for In Vivo Synergistic Anticancer Therapy. 2021 Nov 8 2
3 32239594 Plantamajoside inhibits the proliferation and epithelial-to-mesenchymal transition in hepatocellular carcinoma cells via modulating hypoxia-inducible factor-1α-dependent gene expression. 2020 Aug 2
4 30046956 Extracts of Celastrus Orbiculatus Inhibit Cancer Metastasis by Down-regulating Epithelial-Mesenchymal Transition in Hypoxia-Induced Human Hepatocellular Carcinoma Cells. 2019 May 1
5 30676731 Targeted Co-delivery of the Iron Chelator Deferoxamine and a HIF1α Inhibitor Impairs Pancreatic Tumor Growth. 2019 Feb 26 1
6 30881515 Hypoxia-inducible factor-1 signaling pathway influences the sensitivity of HCC827 cells to gefitinib. 2019 Apr 1
7 30939201 Human recombinant FSH induces chemoresistance in human breast cancer cells via HIF-1α activation†. 2019 Jun 1 2
8 31659886 Hypoxia Mediates Runt-Related Transcription Factor 2 Expression via Induction of Vascular Endothelial Growth Factor in Periodontal Ligament Stem Cells. 2019 Nov 30 2
9 29344650 Adrenomedullin serves a role in the humoral pathway of delayed remote ischemic preconditioning via a hypoxia-inducible factor-1α-associated mechanism. 2018 Mar 1
10 28260147 Establishment and characterization of a squamous cell carcinoma cell line, designated hZK-1, derived from a metastatic lymph node tumor of the tongue. 2017 Oct 1
11 28978999 Low-dose YC-1 combined with glucose and insulin selectively induces apoptosis in hypoxic gastric carcinoma cells by inhibiting anaerobic glycolysis. 2017 Oct 4 1
12 25781495 Renalase contributes to the renal protection of delayed ischaemic preconditioning via the regulation of hypoxia-inducible factor-1α. 2015 Jun 1
13 25824695 Hypoxia regulates the expression and localization of CCAAT/enhancer binding protein α by hypoxia inducible factor-1α in bladder transitional carcinoma cells. 2015 Aug 2
14 26711814 Cycling hypoxia induces chemoresistance through the activation of reactive oxygen species-mediated B-cell lymphoma extra-long pathway in glioblastoma multiforme. 2015 Dec 28 1
15 24304276 Interlinking of hypoxia and estrogen in thyroid cancer progression. 2014 2
16 24549370 Inactivation of von Hippel-Lindau increases ovarian cancer cell aggressiveness through the HIF1α/miR-210/VMP1 signaling pathway. 2014 May 2
17 23123638 The anticancer agent YC-1 suppresses progestin-stimulated VEGF in breast cancer cells and arrests breast tumor development. 2013 Jan 1
18 23311761 The migration of neural progenitor cell mediated by SDF-1 is NF-κB/HIF-1α dependent upon hypoxia. 2013 Mar 2
19 22087807 Lipopolysaccharide and hypoxia-induced HIF-1 activation in human gingival fibroblasts. 2012 Jun 1
20 22217342 HIF-1 activation induces doxorubicin resistance in MCF7 3-D spheroids via P-glycoprotein expression: a potential model of the chemo-resistance of invasive micropapillary carcinoma of the breast. 2012 Jan 4 3
21 22507221 YC-1 exerts inhibitory effects on MDA-MB-468 breast cancer cells by targeting EGFR in vitro and in vivo under normoxic condition. 2012 May 3
22 23088607 Hypoxia and estrogen are functionally equivalent in breast cancer-endothelial cell interdependence. 2012 Oct 22 2
23 20977428 Effects of YC-1 targeting hypoxia-inducible factor 1 alpha in oesophageal squamous carcinoma cell line Eca109 cells. 2011 May 1
24 21523559 Hypoxia effects on proangiogenic factors in human umbilical vein endothelial cells: functional role of the peptide somatostatin. 2011 Jun 1
25 17312464 Effects of YC-1 on hypoxia-inducible factor 1-driven transcription activity, cell proliferative vitality, and apoptosis in hypoxic human pancreatic cancer cells. 2007 Mar 1
26 16024616 A noninvasive approach for assessing tumor hypoxia in xenografts: developing a urinary marker for hypoxia. 2005 Jul 15 1