| 1 |
33024904 | Significant difference between sirolimus and paclitaxel nanoparticles in anti-proliferation effect in normoxia and hypoxia: The basis of better selection of atherosclerosis treatment. | 2021 Mar |
1 |
| 2 |
32692750 | Retraction: Rapamycin Inhibits Proliferation of Hemangioma Endothelial Cells by Reducing HIF-1-Dependent Expression of VEGF. | 2020 |
1 |
| 3 |
33092063 | SFCE-RAPIRI Phase I Study of Rapamycin Plus Irinotecan: A New Way to Target Intra-Tumor Hypoxia in Pediatric Refractory Cancers. | 2020 Oct 20 |
1 |
| 4 |
31221957 | Hypoxia and aging. | 2019 Jun 20 |
1 |
| 5 |
31383843 | O-cyclic phytosphingosine-1-phosphate stimulates HIF1α-dependent glycolytic reprogramming to enhance the therapeutic potential of mesenchymal stem cells. | 2019 Aug 5 |
2 |
| 6 |
31640284 | Constitutive or Induced HIF-2 Addiction is Involved in Resistance to Anti-EGFR Treatment and Radiation Therapy in HNSCC. | 2019 Oct 21 |
1 |
| 7 |
31763809 | Oxygen-Self-Supplying and HIF-1α-Inhibiting Core-Shell Nanosystem for Hypoxia-Resistant Photodynamic Therapy. | 2019 Dec 26 |
1 |
| 8 |
29190547 | Low-folate stress reprograms cancer stem cell-like potentials and bioenergetics metabolism through activation of mTOR signaling pathway to promote in vitro invasion and in vivo tumorigenicity of lung cancers. | 2018 Mar |
1 |
| 9 |
30219159 | Silent Information Regulator 1 Negatively Regulates Atherosclerotic Angiogenesis via Mammalian Target of Rapamycin Complex 1 Signaling Pathway. | 2018 Aug |
1 |
| 10 |
28356986 | Hypoxia regulates CD44 expression via hypoxia-inducible factor-1α in human gastric cancer cells. | 2017 Feb |
1 |
| 11 |
28542038 | Hypoxia as a target for drug combination therapy of liver cancer. | 2017 Aug |
1 |
| 12 |
28963126 | EGF regulation of proximal tubule cell proliferation and VEGF-A secretion. | 2017 Sep |
1 |
| 13 |
26620226 | Expression of hypoxia-inducible factor-1 by trophectoderm cells in response to hypoxia and epidermal growth factor. | 2016 Jan 8 |
1 |
| 14 |
26937175 | Synergistic roles of p53 and HIF1α in human renal cell carcinoma-cell apoptosis responding to the inhibition of mTOR and MDM2 signaling pathways. | 2016 |
2 |
| 15 |
27044634 | SNAIL gene inhibited by hypoxia-inducible factor 1α (HIF-1α) in epithelial ovarian cancer. | 2016 Sep |
1 |
| 16 |
25988388 | Suppression of the proliferation of hypoxia-Induced retinal pigment epithelial cell by rapamycin through the /mTOR/HIF-1α/VEGF/ signaling. | 2015 Jun |
1 |
| 17 |
24018642 | Systematic combination screening reveals synergism between rapamycin and sunitinib against human lung cancer. | 2014 Jan 1 |
1 |
| 18 |
24496328 | M(o)TOR of pseudo-hypoxic state in aging: rapamycin to the rescue. | 2014 |
1 |
| 19 |
25166211 | Hypoxia promotes uveal melanoma invasion through enhanced Notch and MAPK activation. | 2014 |
1 |
| 20 |
23762265 | Insulin promotes glucose consumption via regulation of miR-99a/mTOR/PKM2 pathway. | 2013 |
1 |
| 21 |
23819061 | Stathmin Regulates Hypoxia-Inducible Factor-1α Expression through the Mammalian Target of Rapamycin Pathway in Ovarian Clear Cell Adenocarcinoma. | 2013 |
2 |
| 22 |
21567203 | Rapamycin decreases survivin expression to induce NSCLC cell apoptosis under hypoxia through inhibiting HIF-1α induction. | 2012 Jan |
3 |
| 23 |
22117756 | Rapamycin inhibits transforming growth factor β-induced peritoneal angiogenesis by blocking the secondary hypoxic response. | 2012 Aug |
1 |
| 24 |
22900063 | Rapamycin inhibits proliferation of hemangioma endothelial cells by reducing HIF-1-dependent expression of VEGF. | 2012 |
1 |
| 25 |
21252047 | Mammalian target of rapamycin mediates the angiogenic effects of leptin in human hepatic stellate cells. | 2011 Aug |
1 |
| 26 |
21521942 | The purpose of the HIF-1/PHD feedback loop: to limit mTOR-induced HIF-1α. | 2011 May 15 |
1 |
| 27 |
21964931 | Ginsenoside-Rg1 mediates a hypoxia-independent upregulation of hypoxia-inducible factor-1α to promote angiogenesis. | 2011 Dec |
1 |
| 28 |
20139176 | Inflammatory stimulation and hypoxia cooperatively activate HIF-1{alpha} in bronchial epithelial cells: involvement of PI3K and NF-{kappa}B. | 2010 May |
1 |
| 29 |
20156674 | Treating triple-negative breast cancer by a combination of rapamycin and cyclophosphamide: an in vivo bioluminescence imaging study. | 2010 Apr |
2 |
| 30 |
20335389 | EP1 prostanoid receptor coupling to G i/o up-regulates the expression of hypoxia-inducible factor-1 alpha through activation of a phosphoinositide-3 kinase signaling pathway. | 2010 Jun |
1 |
| 31 |
20554536 | A novel Ca2+/calmodulin antagonist HBC inhibits angiogenesis and down-regulates hypoxia-inducible factor. | 2010 Aug 13 |
1 |
| 32 |
18781596 | Activation of HIF-1alpha in exponentially growing cells via hypoxic stimulation is independent of the Akt/mTOR pathway. | 2009 Jan |
3 |
| 33 |
18845636 | Role of the phosphatidylinositol-3-kinase and extracellular regulated kinase pathways in the induction of hypoxia-inducible factor (HIF)-1 activity and the HIF-1 target vascular endothelial growth factor in ovarian granulosa cells in response to follicle-stimulating hormone. | 2009 Feb |
1 |
| 34 |
19002496 | Sirolimus inhibits the growth and metastatic progression of hepatocellular carcinoma. | 2009 May |
3 |
| 35 |
19190131 | Marked activity of irinotecan and rapamycin combination toward colon cancer cells in vivo and in vitro is mediated through cooperative modulation of the mammalian target of rapamycin/hypoxia-inducible factor-1alpha axis. | 2009 Feb 15 |
1 |
| 36 |
19347904 | Rapamycin selectively reduces the association of transcripts containing complex 5' UTRs with ribosomes in C4-2B prostate cancer cells. | 2009 Jun 1 |
1 |
| 37 |
19789218 | Oltipraz and dithiolethione congeners inhibit hypoxia-inducible factor-1alpha activity through p70 ribosomal S6 kinase-1 inhibition and H2O2-scavenging effect. | 2009 Oct |
1 |
| 38 |
17645504 | Plasticity of ovarian cancer cell SKOV3ip and vasculogenic mimicry in vivo. | 2008 May-Jun |
1 |
| 39 |
18394010 | Hypoxia-inducible factor-2alpha: effect on radiation sensitivity and differential regulation by an mTOR inhibitor. | 2008 Aug |
1 |
| 40 |
18945681 | Differential dependence of hypoxia-inducible factors 1 alpha and 2 alpha on mTORC1 and mTORC2. | 2008 Dec 12 |
1 |
| 41 |
17483438 | Differential regulation of vascular endothelial growth factor by Akt and mammalian target of rapamycin inhibitors in cell lines derived from childhood solid tumors. | 2007 May |
1 |
| 42 |
17502379 | Hypoxia-inducible factor 1alpha is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif. | 2007 Jul 13 |
1 |
| 43 |
17968710 | Sirolimus inhibits human pancreatic carcinoma cell proliferation by a mechanism linked to the targeting of mTOR/HIF-1 alpha/VEGF signaling. | 2007 Nov |
3 |
| 44 |
16412252 | Hypoxia-inducible factor-1alpha polymorphisms and TSC1/2 mutations are complementary in head and neck cancers. | 2006 Jan 16 |
1 |
| 45 |
16515634 | Hypoxia-inducible factor 1alpha (HIF-1alpha) correlated with tumor growth and apoptosis in ovarian cancer. | 2006 Jan-Feb |
2 |
| 46 |
16627974 | Hypoxic microenvironment as a cradle for melanoma development and progression. | 2006 May |
1 |
| 47 |
16849522 | Akt1 activation can augment hypoxia-inducible factor-1alpha expression by increasing protein translation through a mammalian target of rapamycin-independent pathway. | 2006 Jul |
2 |
| 48 |
17190738 | FK506: an immunosuppressive agent preserving HIF-1 activity. | 2006 |
1 |
| 49 |
15944259 | TCR engagement increases hypoxia-inducible factor-1 alpha protein synthesis via rapamycin-sensitive pathway under hypoxic conditions in human peripheral T cells. | 2005 Jun 15 |
1 |
| 50 |
16277894 | [Primary study of vasculogenic mimicry induced by hypoxia in epithelial ovarian carcinoma]. | 2005 Oct |
2 |