Hydrogen Peroxide

hypoxia inducible factor 1 subunit alpha ; Homo sapiens







63 Article(s)
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1 34742454 O-carboxymethyl chitosan based pH/hypoxia-responsive micelles relieve hypoxia and induce ROS in tumor microenvironment. 2022 Jan 1 2
2 34965614 Reshaping the Tumor Immune Microenvironment Based on a Light-Activated Nanoplatform for Efficient Cancer Therapy. 2022 Mar 1
3 35007563 STING up-regulates VEGF expression in oxidative stress-induced senescence of retinal pigment epithelium via NF-κB/HIF-1α pathway. 2022 Mar 15 1
4 35380485 HIF-1α protects osteoblasts from ROS-induced apoptosis. 2022 Feb 4
5 35401926 Chitosan Oligosaccharides Alleviate H2O2-stimulated Granulosa Cell Damage via HIF-1α Signaling Pathway. 2022 3
6 35565979 An Enhanced Photothermal Therapeutic Iridium Hybrid Platform Reversing the Tumor Hypoxic Microenvironment. 2022 Apr 19 1
7 33738869 Differentiation of Hodgkin lymphoma cells by reactive oxygen species and regulation by heme oxygenase-1 through HIF-1α. 2021 Jun 1
8 34204881 Outcomes of Deferoxamine Action on H2O2-Induced Growth Inhibition and Senescence Progression of Human Endometrial Stem Cells. 2021 Jun 3 1
9 34558885 Diallyl Trisulfide Suppresses High-Glucose-Induced Cardiomyocyte Apoptosis by Targeting Reactive Oxygen Species-Mediated Hypoxia-Inducible Factor-1α/Insulin-like Growth Factor Binding Protein 3 Activation. 2021 Oct 6 1
10 34836938 Reciprocal regulation of LOXL2 and HIF1α drives the Warburg effect to support pancreatic cancer aggressiveness. 2021 Nov 26 2
11 31981961 MicroRNA and heme oxygenase-1 in allergic disease. 2020 Mar 1
12 32122653 Nitroprusside induces melanoma ferroptosis with serum supplementation and prolongs survival under serum depletion or hypoxia. 2020 May 7 1
13 30686776 HIF-1α protects against oxidative stress by directly targeting mitochondria. 2019 Jul 1
14 31011561 Preconditioning of Mesenchymal Stem Cells with Non-Toxic Concentration of Hydrogen Peroxide Against Oxidative Stress Induced Cell Death: The Role of Hypoxia-Inducible Factor-1. 2019 Feb 2
15 31310363 Glutathione peroxidase 3 (GPX3) suppresses the growth of melanoma cells through reactive oxygen species (ROS)-dependent stabilization of hypoxia-inducible factor 1-α and 2-α. 2019 Nov 2
16 31389949 Development of an interactive tumor vascular suppression strategy to inhibit multidrug resistance and metastasis with pH/H2O2 responsive and oxygen-producing nanohybrids. 2019 Aug 7 4
17 31524211 Bifunctional liposomes reduce the chemotherapy resistance of doxorubicin induced by reactive oxygen species. 2019 Nov 1 4
18 29138796 Reactive oxygen species induce injury of the intestinal epithelium during hyperoxia. 2018 Jan 1
19 29258824 Hypoxia-increased RAGE expression regulates chemotaxis and pro-inflammatory cytokines release through nuclear translocation of NF-κ B and HIF1α in THP-1 cells. 2018 Jan 15 1
20 29287724 PARIS reprograms glucose metabolism by HIF-1α induction in dopaminergic neurodegeneration. 2018 Jan 22 1
21 29396728 Pharmacologic ascorbate (P-AscH-) suppresses hypoxia-inducible Factor-1α (HIF-1α) in pancreatic adenocarcinoma. 2018 Feb 1
22 30062712 Ionic silicon improves endothelial cells' survival under toxic oxidative stress by overexpressing angiogenic markers and antioxidant enzymes. 2018 Nov 1
23 30247915 Peroxidase-Mimicking Nanoassembly Mitigates Lipopolysaccharide-Induced Endotoxemia and Cognitive Damage in the Brain by Impeding Inflammatory Signaling in Macrophages. 2018 Oct 10 1
24 27132006 Amperometric sensing of HIF1α expressed in cancer cells and the effect of hypoxic mimicking agents. 2016 Sep 15 1
25 27637085 Dual oxidase 2 and pancreatic adenocarcinoma: IFN-γ-mediated dual oxidase 2 overexpression results in H2O2-induced, ERK-associated up-regulation of HIF-1α and VEGF-A. 2016 Oct 18 1
26 25433027 HIF1A-dependent increase in endothelin 2 levels in granulosa cells: role of hypoxia, LH/cAMP, and reactive oxygen species. 2015 Jan 2
27 24184535 Indole conjugated silica and magnetic nanoparticles as inhibitors of HIF. 2014 Feb 1 1
28 24634836 Hydrogen peroxide sensing, signaling and regulation of transcription factors. 2014 2
29 25108166 Quercetin attenuates cell apoptosis of oxidant-stressed SK-N-MC cells while suppressing up-regulation of the defensive element, HIF-1α. 2014 Sep 26 1
30 25317019 Bilirubin activates transcription of HIF-1α in human proximal tubular cells cultured in the physiologic oxygen content. 2014 Sep 2
31 22986926 Oxidative stress produced by xanthine oxidase induces apoptosis in human extravillous trophoblast cells. 2013 1
32 23626851 High concentrations of L-ascorbic acid specifically inhibit the growth of human leukemic cells via downregulation of HIF-1α transcription. 2013 1
33 22223846 Hypoxia-inducible factor-1α inhibition by a pyrrolopyrazine metabolite of oltipraz as a consequence of microRNAs 199a-5p and 20a induction. 2012 Mar 1
34 22307228 Transforming growth factor-β1 induces glutathione peroxidase-1 and protects from H2O2-induced cell death in colon cancer cells via the Smad2/ERK1/2/HIF-1α pathway. 2012 May 1
35 22569265 Vasohibin induces prolyl hydroxylase-mediated degradation of hypoxia-inducible factor-1α in human umbilical vein endothelial cells. 2012 Apr 5 3
36 21239473 The HIF-1-inducible lysyl oxidase activates HIF-1 via the Akt pathway in a positive regulation loop and synergizes with HIF-1 in promoting tumor cell growth. 2011 Mar 1 1
37 19998339 ERK/MAPK activation involves hypoxia-induced MGr1-Ag/37LRP expression and contributes to apoptosis resistance in gastric cancer. 2010 Aug 15 1
38 21103079 Significance of p27 as potential biomarker for intracellular oxidative status. 2010 Oct 1
39 21150341 Aspartyl-(asparaginyl) beta-hydroxylase, hypoxia-inducible factor-alpha and Notch cross-talk in regulating neuronal motility. 2010 Sep-Oct 3
40 19147752 Mitochondrial mutations contribute to HIF1alpha accumulation via increased reactive oxygen species and up-regulated pyruvate dehydrogenease kinase 2 in head and neck squamous cell carcinoma. 2009 Jan 15 2
41 19789218 Oltipraz and dithiolethione congeners inhibit hypoxia-inducible factor-1alpha activity through p70 ribosomal S6 kinase-1 inhibition and H2O2-scavenging effect. 2009 Oct 3
42 20022860 The GOX/CAT system: a novel enzymatic method to independently control hydrogen peroxide and hypoxia in cell culture. 2009 1
43 17942596 Hypoxia-inducible factor-1alpha stabilization in nonhypoxic conditions: role of oxidation and intracellular ascorbate depletion. 2008 Jan 2
44 18258605 Reactive oxygen species stabilize hypoxia-inducible factor-1 alpha protein and stimulate transcriptional activity via AMP-activated protein kinase in DU145 human prostate cancer cells. 2008 Apr 1
45 18559422 Reactive oxygen species regulate hypoxia-inducible factor 1alpha differentially in cancer and ischemia. 2008 Aug 3
46 18702304 [Hypoxia induced HIF-1 accumulation and VEGF expression in gastric epithelial mucosa cell: involvement of ERK1/2 and PI3K/Akt]. 2008 May-Jun 1
47 16774940 Reactive oxygen species regulate insulin-induced VEGF and HIF-1alpha expression through the activation of p70S6K1 in human prostate cancer cells. 2007 Jan 2
48 17561100 HIF-1alpha activation by a redox-sensitive pathway mediates cyanide-induced BNIP3 upregulation and mitochondrial-dependent cell death. 2007 Jul 1 1
49 17562787 The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production. 2007 Jun 18 2
50 16427606 Hypoxia dysregulates the production of adiponectin and plasminogen activator inhibitor-1 independent of reactive oxygen species in adipocytes. 2006 Mar 10 1