Aspirin

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ; Homo sapiens







39 Article(s)
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1 35171329 Meta-analysis of aspirin-guided therapy of colorectal cancer. 2022 Jun 2
2 33574709 siRNA Knockdown of REDD1 Facilitates Aspirin-Mediated Dephosphorylation of mTORC1 Target 4E-BP1 in MDA-MB-468 Human Breast Cancer Cell Line. 2021 1
3 34537546 Acetylsalicylic acid suppression of the PI3K pathway as a novel medical therapy for head and neck lymphatic malformations. 2021 Dec 3
4 34638442 Superior Overall Survival in Patients with Colorectal Cancer, Regular Aspirin Use, and Combined Wild-Type PIK3CA and KRAS-Mutated Tumors. 2021 Oct 1 3
5 31904094 A comprehensive in vivo and mathematic modeling-based kinetic characterization for aspirin-induced chemoprevention in colorectal cancer. 2020 Jul 10 1
6 32000660 Aspirin has a better effect on PIK3CA mutant colorectal cancer cells by PI3K/Akt/Raptor pathway. 2020 Jan 30 7
7 32326897 Different associations of tumor PIK3CA mutations and clinical outcomes according to aspirin use among women with metastatic hormone receptor positive breast cancer. 2020 Apr 23 5
8 32365457 Deactivation of Glutaminolysis Sensitizes PIK3CA-Mutated Colorectal Cancer Cells to Aspirin-Induced Growth Inhibition. 2020 Apr 30 8
9 32646396 Relationship between aspirin use of esophageal, gastric and colorectal cancer patient survival: a meta-analysis. 2020 Jul 9 2
10 31262687 Aspirin Treatment Effect and Association with PIK3CA Mutation in Breast Cancer: A Biomarker Analysis. 2019 Oct 3
11 29153543 [Aspirin and colorectal cancer]. 2018 Feb 1
12 29402752 Aspirin versus placebo in stage III or high-risk stage II colon cancer with PIK3CA mutation: A French randomised double-blind phase III trial (PRODIGE 50-ASPIK). 2018 Mar 2
13 29850157 Aspirin acts in esophageal cancer: a brief review. 2018 Apr 1
14 27800646 Examining the impact of regular aspirin use and PIK3CA mutations on survival in stage 2 colon cancer. 2017 Jan 1
15 27940576 Aspirin Suppresses Growth in PI3K-Mutant Breast Cancer by Activating AMPK and Inhibiting mTORC1 Signaling. 2017 Feb 1 5
16 28154202 Aspirin-Induced Chemoprevention and Response Kinetics Are Enhanced by PIK3CA Mutations in Colorectal Cancer Cells. 2017 Mar 6
17 28219002 Molecular Testing for Gastrointestinal Cancer. 2017 Mar 1
18 28448072 Evaluation of PTGS2 Expression, PIK3CA Mutation, Aspirin Use and Colon Cancer Survival in a Population-Based Cohort Study. 2017 Apr 27 1
19 28525374 The effect of rapamycin, NVP-BEZ235, aspirin, and metformin on PI3K/AKT/mTOR signaling pathway of PIK3CA-related overgrowth spectrum (PROS). 2017 Jul 11 1
20 28849118 Aspirin inhibits the proliferation of human uterine leiomyoma cells by downregulation of K‑Ras‑p110α interaction. 2017 Oct 5
21 29152088 Aspirin exerts high anti-cancer activity in PIK3CA-mutant colon cancer cells. 2017 Oct 20 14
22 29552640 Integration of pharmacology, molecular pathology, and population data science to support precision gastrointestinal oncology. 2017 1
23 26712086 PIK3CA Mutation, Aspirin Use after Diagnosis and Survival of Colorectal Cancer. A Systematic Review and Meta-analysis of Epidemiological Studies. 2016 May 4
24 26915040 Mutations in PIK3CA sensitize breast cancer cells to physiologic levels of aspirin. 2016 Feb 6
25 27096951 Aspirin in the Treatment of Cancer: Reductions in Metastatic Spread and in Mortality: A Systematic Review and Meta-Analyses of Published Studies. 2016 1
26 27268661 Mutations in PIK3CA Sensitize Breast Cancer Cells to Physiologic Levels of Aspirin. 2016 1
27 25239119 Aspirin use after diagnosis but not prediagnosis improves established colorectal cancer survival: a meta-analysis. 2015 Sep 2
28 25388762 Role of p38 MAPK in enhanced human cancer cells killing by the combination of aspirin and ABT-737. 2015 Feb 2
29 25549537 Impact of regular aspirin use on overall and cancer-specific survival in patients with colorectal cancer harboring a PIK3CA mutation. 2015 Apr 3
30 23792451 Discovery of colorectal cancer PIK3CA mutation as potential predictive biomarker: power and promise of molecular pathological epidemiology. 2014 Jun 5 3
31 24355100 DNA testing and molecular screening for colon cancer. 2014 Mar 1
32 24624362 PIK3CA in Colorectal Cancer. 2014 1
33 24840525 Aspirin in gastrointestinal oncology: new data on an old friend. 2014 Jul 1
34 25180765 Relationship between aspirin use after diagnosis of colorectal cancer and patient survival: a meta-analysis of observational studies. 2014 Nov 25 1
35 23207797 Potential biomarker for aspirin use in colorectal cancer therapy. 2013 Jan 2
36 24062397 Evaluation of PIK3CA mutation as a predictor of benefit from nonsteroidal anti-inflammatory drug therapy in colorectal cancer. 2013 Dec 1 5
37 24166520 Aspirin therapy for colorectal cancer with PIK3CA mutation: simply complex! 2013 Dec 1 1
38 25332957 Aspirin for colorectal cancer with PIK3CA mutations: the rising of the oldest targeted therapy? 2013 Jul 1
39 23094721 Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival. 2012 Oct 25 6