Bicarbonates

carbonic anhydrase 2 ; Homo sapiens







78 Article(s)
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1 35164091 Design, Synthesis and Molecular Docking Study of Novel 3-Phenyl-β-Alanine-Based Oxadiazole Analogues as Potent Carbonic Anhydrase II Inhibitors. 2022 Jan 26 2
2 34255561 Discovery of Natural Compounds as Potential Inhibitors of Human Carbonic Anhydrase II: An Integrated Virtual Screening, Docking, and Molecular Dynamics Simulation Study. 2021 Aug 2
3 34757723 Design of a Superpositively Charged Enzyme: Human Carbonic Anhydrase II Variant with Ferritin Encapsulation and Immobilization. 2021 Nov 30 2
4 32244293 Aspirin: A Suicide Inhibitor of Carbonic Anhydrase II. 2020 Mar 31 2
5 32969493 Carbonic anhydrases enhance activity of endogenous Na-H exchangers and not the electrogenic Na/HCO3 cotransporter NBCe1-A, expressed in Xenopus oocytes. 2020 Dec 1
6 33335888 Quinazolinones as Competitive Inhibitors of Carbonic Anhydrase-II (Human and Bovine): Synthesis, in-vitro, in-silico, Selectivity, and Kinetics Studies. 2020 2
7 31690045 Mechanism of Action of Non-Synonymous Single Nucleotide Variations Associated with α-Carbonic Anhydrase II Deficiency. 2019 Nov 4 4
8 29354275 Active-site solvent replenishment observed during human carbonic anhydrase II catalysis. 2018 Jan 1 2
9 29427171 CO2/bicarbonate modulates cone photoreceptor ROS-GC1 and restores its CORD6-linked catalytic activity. 2018 Nov 1
10 29971013 Exploring the Potential Roles of Band 3 and Aquaporin-1 in Blood CO2 Transport-Inspired by Comparative Studies of Glycophorin B-A-B Hybrid Protein GP.Mur. 2018 3
11 28596233 Adaptable interaction between aquaporin-1 and band 3 reveals a potential role of water channel in blood CO2 transport. 2017 Oct 1
12 30023582 Network of Conformational Transitions Revealed by Molecular Dynamics Simulations of the Carbonic Anhydrase II Apo-Enzyme. 2017 Nov 30 2
13 26041446 Carbonic anhydrase II binds to and increases the activity of the epithelial sodium-proton exchanger, NHE3. 2015 Aug 15 2
14 24914985 Structural elucidation of the hormonal inhibition mechanism of the bile acid cholate on human carbonic anhydrase II. 2014 Jun 1
15 23840420 Comparison and analysis of zinc and cobalt-based systems as catalytic entities for the hydration of carbon dioxide. 2013 1
16 23878365 Activity and distribution of intracellular carbonic anhydrase II and their effects on the transport activity of anion exchanger AE1/SLC4A1. 2013 Oct 15 4
17 23030313 Revisiting zinc coordination in human carbonic anhydrase II. 2012 Oct 15 1
18 21145876 Kinetic and crystallographic studies of the role of tyrosine 7 in the active site of human carbonic anhydrase II. 2011 Feb 15 1
19 21377369 Purification and inhibition studies with anions and sulfonamides of an α-carbonic anhydrase from the Antarctic seal Leptonychotes weddellii. 2011 Mar 15 1
20 21543742 An intramolecular transport metabolon: fusion of carbonic anhydrase II to the COOH terminus of the Cl(-)/HCO(3)(-)exchanger, AE1. 2011 Aug 7
21 19879980 Evaluating the role of carbonic anhydrases in the transport of HCO3--related species. 2010 Feb 11
22 20025241 Neutron structure of human carbonic anhydrase II: implications for proton transfer. 2010 Jan 26 1
23 20175995 A survey of carbonic anhydrase mRNA expression in enamel cells. 2010 Mar 19 1
24 21151921 A host defense mechanism involving CFTR-mediated bicarbonate secretion in bacterial prostatitis. 2010 Dec 7 1
25 19011010 Studies on bicarbonate transporters and carbonic anhydrase in porcine nonpigmented ciliary epithelium. 2009 Apr 1
26 19583303 Apo-human carbonic anhydrase II revisited: implications of the loss of a metal in protein structure, stability, and solvent network. 2009 Aug 11 1
27 18671353 Origins of enhanced proton transport in the Y7F mutant of human carbonic anhydrase II. 2008 Aug 27 1
28 17090540 Evidence against a direct interaction between intracellular carbonic anhydrase II and pure C-terminal domains of SLC4 bicarbonate transporters. 2007 Jan 12 4
29 17164835 The role of carbonic anhydrases in renal physiology. 2007 Jan 1
30 17319692 Atomic crystal and molecular dynamics simulation structures of human carbonic anhydrase II: insights into the proton transfer mechanism. 2007 Mar 20 1
31 17353189 Carbonic anhydrase II increases the activity of the human electrogenic Na+/HCO3- cotransporter. 2007 May 4 1
32 17504129 The development of topically acting carbonic anhydrase inhibitors as anti-glaucoma agents. 2007 1
33 17506534 pKa analysis for the zinc-bound water in human carbonic anhydrase II: Benchmark for "multiscale" QM/MM simulations and mechanistic implications. 2007 Jul 5 2
34 16511248 Production and X-ray crystallographic analysis of fully deuterated human carbonic anhydrase II. 2006 Jan 1 1
35 16773703 Calcium signaling in cholangiocytes. 2006 Jun 14 1
36 16825953 Carbonic anhydrase II in the developing and adult human brain. 2006 Jul 3
37 15667203 Structural and kinetic characterization of active-site histidine as a proton shuttle in catalysis by human carbonic anhydrase II. 2005 Feb 1 1
38 15990874 Metabolon disruption: a mechanism that regulates bicarbonate transport. 2005 Jul 20 1
39 16106378 Proton transfer in a Thr200His mutant of human carbonic anhydrase II. 2005 Nov 1 1
40 14736710 Regulation of the human NBC3 Na+/HCO3- cotransporter by carbonic anhydrase II and PKA. 2004 Jun 3
41 15070393 Zinc solid-state NMR spectroscopy of human carbonic anhydrase: implications for the enzymatic mechanism. 2004 Apr 14 1
42 15218065 Molecular mechanism of kNBC1-carbonic anhydrase II interaction in proximal tubule cells. 2004 Aug 15 2
43 15499994 The bicarbonate transport metabolon. 2004 Jun 10
44 15503807 Localisation of the vacuolar proton pump (V-H+ -ATPase) and carbonic anhydrase II in the human eccrine sweat gland. 2004 May 2
45 12409301 Ca2+ activates cystic fibrosis transmembrane conductance regulator- and Cl- -dependent HCO3 transport in pancreatic duct cells. 2003 Jan 3 1
46 12862489 Influence of backbone conformations of human carbonic anhydrase II on carbon dioxide hydration: hydration pathways and binding of bicarbonate. 2003 Jul 23 2
47 12958404 Computer simulation for effect of Pr(III) on Ca(II) speciation in human interstitial fluid. 2003 Aug 1
48 14692506 Carbonic anhydrase inhibitors. inhibition of cytosolic isozymes I and II and transmembrane, cancer-associated isozyme IX with anions. 2003 Oct 1
49 11934642 Osteoclastic acidification pathways during bone resorption. 2002 Apr 4
50 11994299 The extracellular component of a transport metabolon. Extracellular loop 4 of the human AE1 Cl-/HCO3- exchanger binds carbonic anhydrase IV. 2002 Jul 12 3