Esters

prostaglandin-endoperoxide synthase 2 ; Homo sapiens







12 Article(s)
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Title
Pub. Year
#Total Relationships
1 34592918 New horizons in the roles and associations of COX-2 and novel natural inhibitors in cardiovascular diseases. 2021 Sep 30 1
2 31000626 Fluorescent indomethacin-dansyl conjugates utilize the membrane-binding domain of cyclooxygenase-2 to block the opening to the active site. 2019 May 31 3
3 26704937 Conservative Secondary Shell Substitution In Cyclooxygenase-2 Reduces Inhibition by Indomethacin Amides and Esters via Altered Enzyme Dynamics. 2016 Jan 19 1
4 27229194 A Series of COX-2 Inhibitors Endowed with NO-Releasing Properties: Synthesis, Biological Evaluation, and Docking Analysis. 2016 Aug 19 4
5 25596758 Synthesis, biological evaluation and docking analysis of a new series of methylsulfonyl and sulfamoyl acetamides and ethyl acetates as potent COX-2 inhibitors. 2015 Feb 15 2
6 26392530 Competition and allostery govern substrate selectivity of cyclooxygenase-2. 2015 Oct 6 2
7 24660685 Novel dual inhibitors of nuclear factor-kappa B (NF-κB) and cyclooxygenase- 2 (COX-2): synthesis, in vitro anticancer activity and stability studies of lantadene-non steroidal anti-inflammatory drug (NSAID) conjugates. 2014 1
8 17764958 Novel (E)-2-(aryl)-3-(4-methanesulfonylphenyl)acrylic ester prodrugs possessing a diazen-1-ium-1,2-diolate moiety: design, synthesis, cyclooxygenase inhibition, and nitric oxide release studies. 2007 Nov 1 2
9 15857149 1,5-Diarylpyrrole-3-acetic acids and esters as novel classes of potent and highly selective cyclooxygenase-2 inhibitors. 2005 May 5 1
10 12086537 Combined MEDV-GA-MLR method for QSAR of three panels of steroids, dipeptides, and COX-2 inhibitors. 2002 May-Jun 1
11 12135387 Isoform-selective interaction of cyclooxygenase-2 with indomethacin amides studied by real-time fluorescence, inhibition kinetics, and site-directed mutagenesis. 2002 Jul 30 2
12 10956194 Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors. 2000 Jul 27 2