Dinoprostone

prostaglandin-endoperoxide synthase 2 ; Homo sapiens







950 Article(s)
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Pub. Year
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1 34798265 Microsomal prostaglandin E2 synthase-1 and its inhibitors: Molecular mechanisms and therapeutic significance. 2022 Jan 2
2 34864006 Fisetin suppresses cigarette smoke extract-induced epithelial to mesenchymal transition of airway epithelial cells through regulating COX-2/MMPs/β-catenin pathway. 2022 Jan 5 4
3 34985304 Latest progress in the development of cyclooxygenase-2 pathway inhibitors targeting microsomal prostaglandin E2 synthase-1. 2022 Mar 1
4 35023537 A self-amplifying nanodrug to manipulate the Janus-faced nature of ferroptosis for tumor therapy. 2022 Jan 31 1
5 35103990 Photodynamic Therapy-Induced Cyclooxygenase 2 Expression in Tumor-Draining Lymph Nodes Regulates B-Cell Expression of Interleukin 17 and Neutrophil Infiltration. 2022 Feb 1 5
6 35163465 Up-Regulation of Cyclooxygenase-2 (COX-2) Expression by Temozolomide (TMZ) in Human Glioblastoma (GBM) Cell Lines. 2022 Jan 28 1
7 35163786 miR-132-3p Modulates DUSP9-Dependent p38/JNK Signaling Pathways to Enhance Inflammation in the Amnion Leading to Labor. 2022 Feb 7 2
8 35240193 Down-regulation of the expression of cyclooxygenase-2 and prostaglandin E2 by interleukin-4 is mediated via a reduction in the expression of prostanoid EP4 receptors in HCA-7 human colon cancer cells. 2022 Apr 5 1
9 35242277 Sphingosine 1-Phosphate-Upregulated COX-2/PGE2 System Contributes to Human Cardiac Fibroblast Apoptosis: Involvement of MMP-9-Dependent Transactivation of EGFR Cascade. 2022 8
10 35260536 Adipocyte-derived PGE2 is required for intermittent fasting-induced Treg proliferation and improvement of insulin sensitivity. 2022 Mar 8 3
11 35260562 PGE2 activates EP4 in subchondral bone osteoclasts to regulate osteoarthritis. 2022 Mar 9 4
12 35506586 Orai2 channel regulates prostaglandin E2 production in TNFα/IL1α-stimulated astrocytes. 2022 May 4 1
13 35538811 Betulinic acid exerts anti-inflammatory activity in human periodontal ligament cells stimulated with lipopolysaccharide and/or high glucose. 2022 May 9 2
14 35563840 Lipocalin 2 Deficiency Alters Prostaglandin Biosynthesis and mTOR Signaling Regulation of Thermogenesis and Lipid Metabolism in Adipocytes. 2022 May 3 1
15 35630754 An Osteosarcoma Stem Cell Potent Nickel(II)-Polypyridyl Complex Containing Flufenamic Acid. 2022 May 19 2
16 35634493 The Bradykinin System Contributes to the Regulation of Prostaglandin-Endoperoxide Synthase 2 Expression in Human Amnion Fibroblasts: Implications for Term and Preterm Birth. 2022 2
17 35637203 Behavioral and inflammatory sex differences revealed by celecoxib nanotherapeutic treatment of peripheral neuroinflammation. 2022 May 30 4
18 33035690 Role of cyclooxygenases and prostaglandins in adult brain neurogenesis. 2021 Feb 1
19 33053444 Prostaglandin E receptors as targets for ischemic stroke: Novel evidence and molecular mechanisms of efficacy. 2021 Jan 2
20 33227333 Inhibition of HIF-1α/EP4 axis by hyaluronate-trimethyl chitosan-SPION nanoparticles markedly suppresses the growth and development of cancer cells. 2021 Jan 15 4
21 33275396 Association between plasma prostaglandin E2 level and colorectal cancer. 2021 Jan 1
22 33429006 COX-2 promotes mammary adipose tissue inflammation, local estrogen biosynthesis, and carcinogenesis in high-sugar/fat diet treated mice. 2021 Apr 1 5
23 33429118 PGE2 vs PGF2α in human parturition. 2021 Jan 15 1
24 33440718 Genetic Variations in Prostaglandin E2 Pathway Identified as Susceptibility Biomarkers for Gastric Cancer in an Intermediate Risk European Country. 2021 Jan 11 4
25 33545218 A carrier-free anti-inflammatory platinum (II) self-delivered nanoprodrug for enhanced breast cancer therapy. 2021 Mar 10 5
26 33546238 Non-Steroidal Anti-Inflammatory Drugs in Colorectal Cancer Chemoprevention. 2021 Feb 3 1
27 33557033 2D Nanomaterial, Ti3C2 MXene-Based Sensor to Guide Lung Cancer Therapy and Management. 2021 Feb 4 2
28 33718229 Cyclooxygenase-2 Inhibitor: A Potential Combination Strategy With Immunotherapy in Cancer. 2021 1
29 33768340 Circulating prostaglandin E2: a novel potential prognostic biomarker in patients with hepatocellular carcinoma. 2021 Nov 1
30 33788732 470 nm LED Irradiation Inhibits the Invasiveness of CD133-positive Human Colorectal Cancer Stem Cells by Suppressing the Cyclooxygenase-2/prostaglandin E2 Pathway. 2021 Mar 2
31 33891564 CircRNA hsa_circ_0110102 inhibited macrophage activation and hepatocellular carcinoma progression via miR-580-5p/PPARα/CCL2 pathway. 2021 Apr 23 1
32 33969138 PTGS2 Over-Expression: A Colorectal Carcinoma Initiator not an Invasive Factor. 2021 Jan 4
33 34150019 Cyclooxygenase-2 expressed hepatocellular carcinoma induces cytotoxic T lymphocytes exhaustion through M2 macrophage polarization. 2021 3
34 34185432 C/EBPδ drives key endocrine signals in the human amnion at parturition. 2021 Jun 1
35 34198336 The interleukin 6 trans-signaling increases prostaglandin E2 production in human granulosa cells†. 2021 Nov 15 2
36 34246631 Tyrosine phosphatase STEP is a key regulator of glutamate-induced prostaglandin E2 release from neurons. 2021 Aug 3
37 34295923 Nicotinamide Mononucleotide Alleviates LPS-Induced Inflammation and Oxidative Stress via Decreasing COX-2 Expression in Macrophages. 2021 2
38 34337939 Fab Fragment of Immunoglobulin Y Modulates NF-κB and MAPK Signaling through TLR4 and αVβ3 Integrin and Inhibits the Inflammatory Effect on R264.7 Macrophages. 2021 Aug 11 2
39 34352171 EP2 Antagonists (2011-2021): A Decade's Journey from Discovery to Therapeutics. 2021 Aug 26 2
40 34366627 Genetic variant of cyclooxygenase-2 in gastric cancer: More inflammation and susceptibility. 2021 Jul 28 1
41 34404424 Identification of novel COX-2 / CYP19A1 axis involved in the mesothelioma pathogenesis opens new therapeutic opportunities. 2021 Aug 17 1
42 34539828 Benefits of α-lipoic acid in high-risk pregnancies (Review). 2021 Nov 1
43 34564973 Atorvastatin inhibits proliferation and promotes apoptosis of colon cancer cells via COX-2/PGE2/β-Catenin Pathway. 2021 Jul-Aug 6
44 34604848 Biosynthetic Crossover of 5-Lipoxygenase and Cyclooxygenase-2 Yields 5-Hydroxy-PGE2 and 5-Hydroxy-PGD2. 2021 Sep 27 1
45 34609050 Celecoxib reduces hepatic vascular resistance in portal hypertension by amelioration of endothelial oxidative stress. 2021 Nov 2
46 34619972 Tumor-associated macrophages increase COX-2 expression promoting endocrine resistance in breast cancer via the PI3K/Akt/mTOR pathway. 2021 Sep 3
47 34945337 Low Intensity Pulsed Ultrasound for Bone Tissue Engineering. 2021 Nov 30 2
48 31867776 High COX-2 expression in cancer-associated fibiroblasts contributes to poor survival and promotes migration and invasiveness in nasopharyngeal carcinoma. 2020 Mar 1
49 31900378 Withdrawal: Cyclooxygenase-2-derived prostaglandin E2 stimulates Id-1 transcription. 2020 Jan 3 1
50 32013063 Photoprotective Activity of Topsentin, A Bis(Indole) Alkaloid from the Marine Sponge Spongosorites genitrix, by Regulation of COX-2 and Mir-4485 Expression in UVB-Irradiated Human Keratinocyte Cells. 2020 Jan 29 4