Tetradecanoylphorbol Acetate

prostaglandin-endoperoxide synthase 2 ; Homo sapiens







104 Article(s)
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51 18090122 Efficacy of sulforaphane is mediated by p38 MAP kinase and caspase-7 activations in ER-positive and COX-2-expressed human breast cancer cells. 2007 Dec 2
52 16371352 Expression of cyclooxygenase-2 is regulated by glycogen synthase kinase-3beta in gastric cancer cells. 2006 Feb 24 1
53 16380122 Hirsutenone inhibits phorbol ester-induced upregulation of COX-2 and MMP-9 in cultured human mammary epithelial cells: NF-kappaB as a potential molecular target. 2006 Jan 23 6
54 16424122 Conjugated linoleic acid attenuates cyclooxygenase-2 transcriptional activity via an anti-AP-1 mechanism in MCF-7 breast cancer cells. 2006 Feb 1
55 16534736 Inhibitory effects of ginsenoside-Rb1 on activation of the 12-O-tetradecanoylphorbol 13-acetate-induced cyclooxygenase-2 promoter. 2006 Feb 6
56 16618699 Cyanidin-3-glucoside, a natural product derived from blackberry, exhibits chemopreventive and chemotherapeutic activity. 2006 Jun 23 1
57 16622456 RNA interference as a key to knockdown overexpressed cyclooxygenase-2 gene in tumour cells. 2006 May 8 2
58 16632868 Reciprocal regulation of cyclooxygenase-2 and 15-hydroxyprostaglandin dehydrogenase expression in A549 human lung adenocarcinoma cells. 2006 Nov 2
59 16728574 VEGF-C and COX-2 expression in papillary thyroid cancer. 2006 Jun 2
60 16870006 Soya isoflavones suppress phorbol 12-myristate 13-acetate-induced COX-2 expression in MCF-7 cells. 2006 Jul 3
61 16889690 Effective chemopreventive activity of genistein against human breast cancer cells. 2006 Jul 31 2
62 16966442 Cyclooxygenase-2 expression in normal and neoplastic canine mammary cell lines. 2006 Sep 1
63 17047069 Selenium regulates cyclooxygenase-2 and extracellular signal-regulated kinase signaling pathways by activating AMP-activated protein kinase in colon cancer cells. 2006 Oct 15 3
64 17062574 Down syndrome candidate region 1 increases the stability of the IkappaBalpha protein: implications for its anti-inflammatory effects. 2006 Dec 22 4
65 15516334 Epidermal peroxisome proliferator-activated receptor gamma as a target for ultraviolet B radiation. 2005 Jan 7 2
66 15567061 Phorbol 12-myristate 13-acetate upregulates cyclooxygenase-2 expression in human pulmonary epithelial cells via Ras, Raf-1, ERK, and NF-kappaB, but not p38 MAPK, pathways. 2005 Mar 6
67 15632146 Expression and function of the nuclear factor of activated T cells in colon carcinoma cells: involvement in the regulation of cyclooxygenase-2. 2005 Mar 11 1
68 15664395 Diversity and similarity in signaling events leading to rapid Cox-2 induction by tumor necrosis factor-alpha and phorbol ester in human endothelial cells. 2005 Feb 15 1
69 15843042 Prostaglandin D(2) and J(2) induce apoptosis in human leukemia cells via activation of the caspase 3 cascade and production of reactive oxygen species. 2005 Apr 15 2
70 16044407 Inhibition of TPA-induced cyclooxygenase-2 (COX-2) expression by apigenin through downregulation of Akt signal transduction in human keratinocytes. 2005 Oct 12
71 16356124 Curcumin inhibits phorbol ester-induced up-regulation of cyclooxygenase-2 and matrix metalloproteinase-9 by blocking ERK1/2 phosphorylation and NF-kappaB transcriptional activity in MCF10A human breast epithelial cells. 2005 Nov-Dec 6
72 14630807 Role of p300 and PCAF in regulating cyclooxygenase-2 promoter activation by inflammatory mediators. 2004 Mar 15 2
73 14729583 Celecoxib inhibits phorbol ester-induced expression of COX-2 and activation of AP-1 and p38 MAP kinase in mouse skin. 2004 May 3
74 12623129 Regulation of cyclooxygenase-2 expression by iloprost in human vascular smooth muscle cells. Role of transcription factors CREB and ICER. 2003 Mar 15 2
75 12707358 Tyrosine phosphorylation of I-kappa B kinase alpha/beta by protein kinase C-dependent c-Src activation is involved in TNF-alpha-induced cyclooxygenase-2 expression. 2003 May 1 2
76 14566822 The effect of nitric oxide on cyclooxygenase-2 (COX-2) overexpression in head and neck cancer cell lines. 2003 Dec 10 2
77 14608118 Inhibition of phorbol ester-induced COX-2 expression by epigallocatechin gallate in mouse skin and cultured human mammary epithelial cells. 2003 Nov 3
78 11836568 Cyclooxygenase-2 expression influences the growth of human large and small cell lung carcinoma lines in athymic mice: impact of an organoselenium compound on growth regulation. 2002 Mar 2
79 11980644 Retinoids and carnosol suppress cyclooxygenase-2 transcription by CREB-binding protein/p300-dependent and -independent mechanisms. 2002 May 1 6
80 12060668 Purification and characterization of a cyclooxygenase-2 and angiogenesis suppressing factor produced by human fibroblasts. 2002 Aug 1
81 11156939 Cell cycle-dependent expression of cyclooxygenase-2 in human fibroblasts. 2001 Feb 1
82 11226820 In vitro based index of topical anti-inflammatory activity to compare a series of NSAIDs. 2001 Mar 2
83 11278336 Peroxisome proliferator-activated receptor gamma ligands suppress the transcriptional activation of cyclooxygenase-2. Evidence for involvement of activator protein-1 and CREB-binding protein/p300. 2001 Apr 13 4
84 11432874 Colocalization and interaction of cyclooxygenase-2 with caveolin-1 in human fibroblasts. 2001 Sep 14 4
85 11489969 Human cytomegalovirus circumvents NF-kappa B dependence in retinal pigment epithelial cells. 2001 Aug 15 1
86 11516798 The effect of dexamethasone on expression of mitogen-induced cyclooxygenase-2 mRNA by amnion-derived (WISH) cells. 2001 Sep 5
87 11689104 Development and use of a gene promoter-based screen to identify novel inhibitors of cyclooxygenase-2 transcription. 2001 Apr 3
88 10788484 Inhibition by extracellular cAMP of phorbol 12-myristate 13-acetate-induced prostaglandin H synthase-2 expression in human pulmonary microvascular endothelial cells. Involvement of an ecto-protein kinase A activity. 2000 May 5 3
89 10811116 Ursolic acid inhibits cyclooxygenase-2 transcription in human mammary epithelial cells. 2000 May 1 5
90 10841038 Differential effects of nitric oxide on the activity of prostaglandin endoperoxide H synthase-1 and -2 in vascular endothelial cells. 2000 Mar 1
91 10946303 TNF-alpha-induced cyclooxygenase-2 expression in human lung epithelial cells: involvement of the phospholipase C-gamma 2, protein kinase C-alpha, tyrosine kinase, NF-kappa B-inducing kinase, and I-kappa B kinase 1/2 pathway. 2000 Sep 1 3
92 11192933 Regulation of cyclooxygenase isoforms in the renal thick ascending limb: effects of extracellular calcium. 2000 Dec 2
93 10190560 Curcumin inhibits cyclooxygenase-2 transcription in bile acid- and phorbol ester-treated human gastrointestinal epithelial cells. 1999 Mar 3
94 10336459 Prostaglandin-endoperoxide H synthase-2 expression in human thyroid epithelium. Evidence for constitutive expression in vivo and in cultured KAT-50 cells. 1999 May 28 2
95 10449199 Role of leukocyte influx in tissue prostaglandin H synthase-2 overexpression induced by phorbol ester and arachidonic acid in skin. 1999 Sep 1 1
96 10668496 Resveratrol inhibits cyclooxygenase-2 transcription in human mammary epithelial cells. 1999 2
97 9661070 Regulation of prostaglandin G/H synthase-2 expression by interleukin-1 in human osteoblast-like cells. 1998 Jul 4
98 9797107 Gene transfer to cultured human endometrial stromal cells: a model to study cyclooxygenase-2 gene regulation. 1998 Oct 1
99 9022759 Induction of cyclooxygenase-1 in a human megakaryoblastic cell line (CMK) differentiated by phorbol ester. 1997 Jan 7 1
100 9215309 Transcriptional regulation of prostaglandin-H synthase-2 gene in human trophoblasts. 1997 Jul 4