Tetradecanoylphorbol Acetate

prostaglandin-endoperoxide synthase 2 ; Homo sapiens







104 Article(s)
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1 34436652 Diclofenac down-regulates COX-2 induced expression of CD44 and ICAM-1 in human HT29 colorectal cancer cells. 2021 Nov 2
2 31506784 Beta-ionone-inhibited proliferation of breast cancer cells by inhibited COX-2 activity. 2019 Oct 2
3 31632572 Tumor-associated macrophages induce invasion and poor prognosis in human gastric cancer in a cyclooxygenase-2/MMP9-dependent manner. 2019 2
4 29371085 (E)-2-Methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) phenol attenuates PMA-induced inflammatory responses in human monocytic cells through PKCδ/JNK/AP-1 pathways. 2018 Apr 15 1
5 30545441 Tat-ATOX1 inhibits inflammatory responses via regulation of MAPK and NF-κB pathways. 2018 Dec 2
6 28108223 Involvement of the antioxidative property of morusin in blocking phorbol ester-induced malignant transformation of JB6 P+ mouse epidermal cells. 2017 Feb 25 2
7 28634425 A Transcriptional Regulatory Role for the Membrane Type-1 Matrix Metalloproteinase in Carcinogen-Induced Inflammasome Gene Expression. 2017 2
8 27035791 Gold-conjugated resveratrol nanoparticles attenuate the invasion and MMP-9 and COX-2 expression in breast cancer cells. 2016 Jun 3
9 27075590 HSP90 Inhibition Suppresses PGE2 Production via Modulating COX-2 and 15-PGDH Expression in HT-29 Colorectal Cancer Cells. 2016 Jun 2
10 25637530 Optical imaging of COX-2: studies on an autofluorescent 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitor. 2015 Feb 27 2
11 25854428 Poly-γ-glutamic acid induces apoptosis via reduction of COX-2 expression in TPA-induced HT-29 human colorectal cancer cells. 2015 Apr 3 1
12 25960826 Effects of docosahexaenoic supplementation and in vitro vitamin C on the oxidative and inflammatory neutrophil response to activation. 2015 1
13 26430963 The transcription factor c-Fos coordinates with histone lysine-specific demethylase 2A to activate the expression of cyclooxygenase-2. 2015 Oct 27 8
14 24345644 COX-2 inhibition prevents the appearance of cutaneous squamous cell carcinomas accelerated by BRAF inhibitors. 2014 Mar 3
15 24742714 Genistein inhibits phorbol ester-induced NF-κB transcriptional activity and COX-2 expression by blocking the phosphorylation of p65/RelA in human mammary epithelial cells. 2014 Oct 3
16 24747121 Sulforaphane inhibits phorbol ester-stimulated IKK-NF-κB signaling and COX-2 expression in human mammary epithelial cells by targeting NF-κB activating kinase and ERK. 2014 Aug 28 8
17 24859472 Metastatic potential in MDA-MB-231 human breast cancer cells is inhibited by proton beam irradiation via the Akt/nuclear factor-κB signaling pathway. 2014 Aug 1
18 24916153 Central role for protein kinase C in oxytocin and epidermal growth factor stimulated cyclooxygenase 2 expression in human myometrial cells. 2014 Jun 10 1
19 22351517 The possible separation of 12-O-tetradecanoylphorbol-13-acetate-induced skin inflammation and hyperplasia by compound A. 2013 Jun 2
20 23408313 Propyl gallate inhibits TPA-induced inflammation via the nuclear factor-κB pathway in human THP-1 monocytes. 2013 Mar 1
21 24065532 Starfish polysaccharides downregulate metastatic activity through the MAPK signaling pathway in MCF-7 human breast cancer cells. 2013 Oct 2
22 22330070 AMP-activated protein kinase mediates T cell activation-induced expression of FasL and COX-2 via protein kinase C theta-dependent pathway in human Jurkat T leukemia cells. 2012 Jun 4
23 22919060 Cross talk between PKC and CREB in the induction of COX-2 by PGF2α in human amnion fibroblasts. 2012 Oct 4
24 22938493 Phorbol ester TPA modulates chemoresistance in the drug sensitive breast cancer cell line MCF-7 by inducing expression of drug efflux transporter ABCG2. 2012 6
25 20422426 Potential role of cyclooxygenase-2 on the regulation of the drug efflux transporter ABCG2 in breast cancer cell lines. 2011 Feb 1
26 20669245 Effects of the black tea polyphenol theaflavin-2 on apoptotic and inflammatory pathways in vitro and in vivo. 2011 Feb 1
27 21907277 Reciprocal regulation of NADPH oxidases and the cyclooxygenase-2 pathway. 2011 Nov 1 2
28 22096365 Low intracellular ATP levels exacerbate carcinogen-induced inflammatory stress response and inhibit in vitro tubulogenesis in human brain endothelial cells. 2011 4
29 19804834 Contribution of reactive oxygen species to migration/invasion of human glioblastoma cells U87 via ERK-dependent COX-2/PGE(2) activation. 2010 Jan 7
30 20582552 Reciprocal correlation between the expression of cyclooxygenase-2 and E-cadherin in human bladder transitional cell carcinomas. 2010 Sep 2
31 20584749 Piceatannol, a catechol-type polyphenol, inhibits phorbol ester-induced NF-{kappa}B activation and cyclooxygenase-2 expression in human breast epithelial cells: cysteine 179 of IKK{beta} as a potential target. 2010 Aug 4
32 20606309 A new cyclooxygenase-2 inhibitor, (1E,4E)-1,5-bis(2-bromophenyl)penta-1,4-dien-3-one (GL63) suppresses cyclooxygenase-2 gene expression in human lung epithelial cancer cells: coupled mRNA stabilization and posttranscriptional inhibition. 2010 5
33 18843292 Tumor-associated macrophage-induced invasion and angiogenesis of human basal cell carcinoma cells by cyclooxygenase-2 induction. 2009 Apr 1
34 19460777 Regulation of protease-activated receptor-1 by vasodilatory prostaglandins via NFAT. 2009 Sep 1 2
35 19715751 Silibinin prevents TPA-induced MMP-9 expression by down-regulation of COX-2 in human breast cancer cells. 2009 Nov 12 6
36 19723105 Effects of cotreatment of 12-O-tetradecanoylphorbol-13-acetate and H2O2 on apoptotic regulation via AMP-activated protein kinase-cyclooxygenase-2 signals. 2009 Aug 9
37 19776509 Involvement of protein kinase C in IL-1beta-induced expression of cyclooxygenase-2 in human gingival fibroblasts. 2009 Sep 2
38 20046424 Cyclooxygenase-2 expression is related to the epithelial-to-mesenchymal transition in human colon cancers. 2009 Dec 31 1
39 20155627 Piceatannol inhibits phorbol ester-induced NF-kappa B activation and COX-2 expression in cultured human mammary epithelial cells. 2009 1
40 17767925 Roles of ERK and p38 mitogen-activated protein kinases in phorbol ester-induced NF-kappaB activation and COX-2 expression in human breast epithelial cells. 2008 Jan 30 4
41 18070609 Inhibition of phorbol ester-dependent peroxiredoxin I gene activation by lipopolysaccharide via phosphorylation of RelA/p65 at serine 276 in monocytes. 2008 Feb 15 1
42 18496814 Wogonin, a bioactive flavonoid in herbal tea, inhibits inflammatory cyclooxygenase-2 gene expression in human lung epithelial cancer cells. 2008 Nov 6
43 18710248 Effects of black soybean [Glycine max (L.) Merr.] seed coats and its anthocyanidins on colonic inflammation and cell proliferation in vitro and in vivo. 2008 Sep 24 1
44 18936204 Rosmarinic acid antagonizes activator protein-1-dependent activation of cyclooxygenase-2 expression in human cancer and nonmalignant cell lines. 2008 Nov 2
45 17404058 Jaceosidin, a pharmacologically active flavone derived from Artemisia argyi, inhibits phorbol-ester-induced upregulation of COX-2 and MMP-9 by blocking phosphorylation of ERK-1 and -2 in cultured human mammary epithelial cells. 2007 Jan 5
46 17404064 Peonidin inhibits phorbol-ester-induced COX-2 expression and transformation in JB6 P+ cells by blocking phosphorylation of ERK-1 and -2. 2007 Jan 3
47 17404068 KG-135 inhibits COX-2 expression by blocking the activation of JNK and AP-1 in phorbol ester-stimulated human breast epithelial cells. 2007 Jan 4
48 17481552 Differential cyclooxygenase-2 transcriptional control in proliferating versus quiescent fibroblasts. 2007 May 1
49 17556653 Interferon-gamma suppresses cyclooxygenase-2 promoter activity by inhibiting C-Jun and C/EBPbeta binding. 2007 Aug 2
50 17944529 Myricetin down-regulates phorbol ester-induced cyclooxygenase-2 expression in mouse epidermal cells by blocking activation of nuclear factor kappa B. 2007 Nov 14 1