nimesulide

prostaglandin-endoperoxide synthase 2 ; Homo sapiens







108 Article(s)
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1 30689999 The relatively selective cyclooxygenase-2 inhibitor nimesulide: What's going on? 2019 Apr 5 1
2 31075744 Nimesulide analogues: From anti-inflammatory to antitumor agents. 2019 Jul 1
3 31480608 Synthesis and Different Effects of Biotinylated PAMAM G3 Dendrimer Substituted with Nimesulide in Human Normal Fibroblasts and Squamous Carcinoma Cells. 2019 Sep 1 4
4 29498006 Inhibition of Cyclooxygenase-2 (COX-2) Initiates Autophagy and Potentiates MPTP-Induced Autophagic Cell Death of Human Neuroblastoma Cells, SH-SY5Y: an Inside in the Pathology of Parkinson's Disease. 2018 Oct 1
5 28666860 Novel 4-acetamide-2-alkylthio-N-acetanilides resembling nimesulide: Synthesis, cell viability evaluation and in silico studies. 2017 Aug 15 1
6 28856805 Reactive astrocyte COX2-PGE2 production inhibits oligodendrocyte maturation in neonatal white matter injury. 2017 Dec 1
7 27325447 Isomeric iodinated analogs of nimesulide: Synthesis, physicochemical characterization, cyclooxygenase-2 inhibitory activity, and transport across Caco-2 cells. 2016 Aug 15 3
8 25250798 Nimesulide-induced fatal acute liver failure in an elderly woman with metastatic biliary adenocarcinoma. A case report. 2015 Jul-Aug 1
9 25637769 Docosahexaenoic acid ester of phloridzin inhibit lipopolysaccharide-induced inflammation in THP-1 differentiated macrophages. 2015 Mar 1
10 26455657 Isomeric methoxy analogs of nimesulide for development of brain cyclooxygense-2 (COX-2)-targeted imaging agents: Synthesis, in vitro COX-2-inhibitory potency, and cellular transport properties. 2015 Nov 1 5
11 23526055 Comparative evaluation of the pain-relieving properties of a lecithinized formulation of curcumin (Meriva(®)), nimesulide, and acetaminophen. 2013 1
12 23973990 Cyclooxygenase-2 (COX-2) inhibition constrains indoleamine 2,3-dioxygenase 1 (IDO1) activity in acute myeloid leukaemia cells. 2013 Aug 22 1
13 22119125 From COX-2 inhibitor nimesulide to potent anti-cancer agent: synthesis, in vitro, in vivo and pharmacokinetic evaluation. 2012 Jan 4
14 22435708 Identification of a class of novel tubulin inhibitors. 2012 Apr 12 2
15 22453101 Nimesulide inhibited the growth of hypopharyngeal carcinoma cells via suppressing Survivin expression. 2012 Mar 27 4
16 23112421 Nimesulide inhibits the proliferation of HepG2 by up-regulation of Smad4. 2012 Sep-Oct 2
17 20803081 mTOR signaling is involved in indomethacin and nimesulide suppression of colorectal cancer cell growth via a COX-2 independent pathway. 2011 Feb 4
18 21349729 Syntheses and characterization of nimesulide derivatives for dual enzyme inhibitors of both cyclooxygenase-1/2 and 5-lipoxygenase. 2011 Mar 15 1
19 21458568 In vitro and in vivo effects of a cyclooxygenase-2 inhibitor nimesulide analog JCC76 in aromatase inhibitors-insensitive breast cancer cells. 2011 Aug 1
20 21807508 Design and synthesis of a biotinylated probe of COX-2 inhibitor nimesulide analog JCC76. 2011 Sep 15 1
21 21862873 Cox-2 inhibitors induce early c-Myc downregulation and lead to expression of differentiation markers in leukemia cells. 2011 Sep 1 1
22 20014174 Trends in the non-steroidal anti-inflammatory drug market in six Central-Eastern European countries based on retail information. 2010 Feb 1
23 20457212 Nimesulide aggravates redox imbalance and calcium dependent mitochondrial permeability transition leading to dysfunction in vitro. 2010 Sep 10 1
24 20542113 COX-2 inhibitor nimesulide analogs are aromatase suppressors in breast cancer cells. 2010 Oct 3
25 20665602 Hydrogen peroxide regulates glucose-regulated protein 78 expression via a cyclooxygenase-2 dependent mechanism. 2010 Sep-Oct 1
26 19152549 Effects of nimesulide, acetylsalicylic acid, ibuprofen and nabumetone on cyclooxygenase-1- and cyclooxygenase-2-mediated prostanoid production in healthy volunteers ex vivo. 2009 Jan 3
27 19428334 A COX-2 inhibitor nimesulide analog selectively induces apoptosis in Her2 overexpressing breast cancer cells via cytochrome c dependent mechanisms. 2009 Jun 15 3
28 19440670 The cyclooxygenase-2 inhibitor nimesulide, a nonsteroidal analgesic, decreases the effect of radiation therapy in head-and-neck cancer cells. 2009 May 1
29 19894761 Cyclooxygenase competitive inhibitors alter tyrosyl radical dynamics in prostaglandin H synthase-2. 2009 Dec 22 1
30 19950766 [Cholestatic hepatitis associated with nimesulide--a case report]. 2009 Sep-Oct 1
31 18197933 COX-2 mRNA expression in esophageal squamous cell carcinoma (ESCC) and effect by NSAID. 2008 1
32 18380483 Synthesis and biological evaluation of novel sulfonanilide compounds as antiproliferative agents for breast cancer. 2008 May-Jun 3
33 18439837 Nimesulide as a promising neuroprotectant in brain ischemia: new experimental evidences. 2008 Apr 2
34 18488158 Effects of a selective cyclooxygenase-2 inhibitor, nimesulide, on the growth of ovarian carcinoma in vivo. 2008 2
35 18509974 [The effect of cyclooxygenase-2 on lymphangiogenesis in breast cancer]. 2008 Jan 15 1
36 18848576 Selective COX-2 inhibitors modulate cellular senescence in human dermal fibroblasts in a catalytic activity-independent manner. 2008 Dec 1
37 17315855 Synthesis and biological evaluation of selective aromatase expression regulators in breast cancer cells. 2007 Apr 5 1
38 17379757 Thrombin inhibits migration of human hepatic myofibroblasts. 2007 Jul 3
39 17652141 Delayed progression of pancreatic intraepithelial neoplasia in a conditional Kras(G12D) mouse model by a selective cyclooxygenase-2 inhibitor. 2007 Aug 1 1
40 17689613 Copper conjugates of nimesulide Schiff bases targeting VEGF, COX and Bcl-2 in pancreatic cancer cells. 2007 Oct 4
41 17983199 [Nimesulide spectrophotometric determination in the visible region]. 2007 Apr-Jun 1
42 18201523 [Expression of cyclooxygenase-2 in pterygium and effects of selective cyclooxygenase-2 inhibitor on human pterygium fibroblasts]. 2007 Oct 1
43 16489006 Stimulation of cyclooxygenase-2 expression by bone-derived transforming growth factor-beta enhances bone metastases in breast cancer. 2006 Feb 15 1
44 16552621 Inhibition of human neuroblastoma in SCID mice by low-dose of selective Cox-2 inhibitor nimesulide. 2006 Jun 2
45 16888076 PGE2 up-regulates EGF-like growth factor biosynthesis in human granulosa cells: new insights into the coordination between PGE2 and LH in ovulation. 2006 Oct 1
46 15567877 Nimesulide, a COX-2 inhibitor, does not reduce lesion size or number in a nude mouse model of endometriosis. 2005 Feb 1
47 15643499 Expression levels of Akt in nimesulide-treated squamous carcinoma cell lines of the head and neck. 2005 Feb 2
48 15705899 Growth stimulation of COX-2-negative pancreatic cancer by a selective COX-2 inhibitor. 2005 Feb 1 3
49 15892673 The effects of non-steroidal anti-inflammatory drugs (selective and non-selective) on the treatment of periodontal diseases. 2005 1
50 16225966 A new potential cyclooxygenase-2 inhibitor, pyridinic analogue of nimesulide. 2005 Dec 1