Aspirin

prostaglandin-endoperoxide synthase 2 ; Homo sapiens







219 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
51 24760190 Aspirin and the risk of colorectal cancer in relation to the expression of 15-hydroxyprostaglandin dehydrogenase (HPGD). 2014 Apr 23 3
52 24908358 Aspirin may modify tumor microenvironment via antiplatelet effect. 2014 Aug 2
53 24958470 IL-1β-mediated repression of microRNA-101 is crucial for inflammation-promoted lung tumorigenesis. 2014 Sep 1 1
54 25012137 Chronic treatment with ticagrelor limits myocardial infarct size: an adenosine and cyclooxygenase-2-dependent effect. 2014 Sep 1
55 25139986 Phospholipase A2 regulates eicosanoid class switching during inflammasome activation. 2014 Sep 2 2
56 25368225 Current concepts in colorectal cancer prevention with cyclooxygenase inhibitors. 2014 Nov 1
57 25612650 Lipoxin A4 mediates aortic contraction via RHOA/RHO kinase, endothelial dysfunction and reactive oxygen species. 2014 2
58 22763923 Association of COX-2 rs20417 with aspirin resistance. 2013 Jan 1
59 23200247 Hybrid fluorescent conjugates of COX-2 inhibitors: search for a COX-2 isozyme imaging cancer biomarker. 2013 Jan 1 2
60 23434193 The role of omega-3 derived resolvins in arthritis. 2013 Jun 1
61 23786234 A mechanistic hypothesis for the aspirin-induced switch in lipid mediator production by cyclooxygenase-2. 2013 Jul 17 1
62 23800934 Aspirin use and risk of colorectal cancer according to BRAF mutation status. 2013 Jun 26 2
63 23810915 PTGS2 (Cyclooxygenase-2) expression and survival among colorectal cancer patients: a systematic review. 2013 Sep 1
64 23884755 Polypharmacy of osteoarthritis: the perfect intestinal storm. 2013 Nov 2
65 23955344 Pre-existent asymmetry in the human cyclooxygenase-2 sequence homodimer. 2013 Oct 4 2
66 24098505 Select dietary phytochemicals function as inhibitors of COX-1 but not COX-2. 2013 1
67 22095955 Aspirin analogues as dual cyclooxygenase-2/5-lipoxygenase inhibitors: synthesis, nitric oxide release, molecular modeling, and biological evaluation as anti-inflammatory agents. 2012 Jan 2 1
68 22245433 Glycosylation of human cyclooxygenase-2 (COX-2) decreases the efficacy of certain COX-2 inhibitors. 2012 Apr 1
69 22252409 Aspirin, nonaspirin nonsteroidal anti-inflammatory drugs, or acetaminophen and risk of ovarian cancer. 2012 Mar 3
70 22429367 Aspirin resistance: clinical significance and genetic polymorphism. 2012 1
71 22588264 Upregulation of cyclooxygenase-2 (COX-2) and microsomal prostaglandin E2 synthase-1 (mPGES-1) in wall of ruptured human cerebral aneurysms: preliminary results. 2012 Jul 1
72 23094721 Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival. 2012 Oct 25 3
73 23240010 Signal transduction pathways (MAPKs, NF-κB, and C/EBP) regulating COX-2 expression in nasal fibroblasts from asthma patients with aspirin intolerance. 2012 4
74 21163909 Human prostaglandin H synthase (hPHS)-1 and hPHS-2 in amphetamine analog bioactivation, DNA oxidation, and cytotoxicity. 2011 Mar 1
75 21435744 [Aspirin in the prevention of colorectal cancer]. 2011 May 1
76 21647198 Gastrointestinal effects of aspirin. 2011 Jun 7 1
77 21703104 Selective cyclooxygenase-2 inhibitor cross-reactivity in aspirin-exacerbated respiratory disease. 2011 May-Jun 1
78 21728052 COX-2 expression predicts worse breast cancer prognosis and does not modify the association with aspirin. 2011 Nov 4
79 19633925 Effects of the inhibition of cyclooxygenase-2 on human esophageal cancer cells: inhibition of cell proliferation and induction of apoptosis. 2010 Mar 1
80 19887674 The contribution of cyclooxygenase-1 and -2 to persistent thromboxane biosynthesis in aspirin-treated essential thrombocythemia: implications for antiplatelet therapy. 2010 Feb 4 4
81 20194532 Asymmetric acetylation of the cyclooxygenase-2 homodimer by aspirin and its effects on the oxygenation of arachidonic, eicosapentaenoic, and docosahexaenoic acids. 2010 Jun 4
82 20397022 Additive inhibition of colorectal cancer cell lines by aspirin and bortezomib. 2010 Jul 6
83 20427397 Cyclooxygenase-2 expression and recurrence of colorectal adenomas: effect of aspirin chemoprevention. 2010 May 3
84 20436486 Cyclooxygenase-2 generates anti-inflammatory mediators from omega-3 fatty acids. 2010 Jun 1
85 20665602 Hydrogen peroxide regulates glucose-regulated protein 78 expression via a cyclooxygenase-2 dependent mechanism. 2010 Sep-Oct 1
86 20697066 Role of vitamin and mineral supplementation and aspirin use in cancer survivors. 2010 Sep 10 2
87 20864907 A summary of recent recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding. 2010 Sep 1
88 21331307 COX-2 Inhibition by Use of Rofecoxib or High Dose Aspirin Enhances ADP-Induced Platelet Aggregation in Fresh Blood. 2010 Oct 21 1
89 22396856 Alzheimer's Disease: Fatty Acids We Eat may be Linked to a Specific Protection via Low-dose Aspirin. 2010 Aug 1
90 19026633 Suppression of Wnt/beta-catenin signaling inhibits prostate cancer cell proliferation. 2009 Jan 5 2
91 19046748 Variation in eicosanoid genes, non-fatal myocardial infarction and ischemic stroke. 2009 Jun 1
92 19295242 Aspirin-induced COX-2 overexpression in monocytes of aspirin-intolerant patients. 2009 10
93 19299662 Low-dose aspirin, coxibs, and other NSAIDS: a clinical mosaic emerges. 2009 Feb 1
94 19306941 Proton pump inhibitors for gastroduodenal damage related to nonsteroidal anti-inflammatory drugs or aspirin: twelve important questions for clinical practice. 2009 Jul 1
95 19671906 Aspirin use and survival after diagnosis of colorectal cancer. 2009 Aug 12 4
96 19755647 Cyclooxygenase-2 polymorphisms, aspirin treatment, and risk for colorectal adenoma recurrence--data from a randomized clinical trial. 2009 Oct 2
97 17495879 Cyclooxygenase polymorphisms and risk of cardiovascular events: the Atherosclerosis Risk in Communities (ARIC) study. 2008 Jan 1
98 18058818 The effects of a COX-2 inhibitor meloxicam on squamous cell carcinoma of the esophagus in vivo. 2008 Apr 1 1
99 18197933 COX-2 mRNA expression in esophageal squamous cell carcinoma (ESCC) and effect by NSAID. 2008 2
100 18209566 Protective effects of aspirin against oxidized LDL-induced inflammatory protein expression in human endothelial cells. 2008 Jan 1