Sulfonamides

prostaglandin-endoperoxide synthase 2 ; Homo sapiens







17 Article(s)
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1 33511940 Dual Human Carbonic Anhydrase/Cyclooxygenase-2 Inhibitors: A Promising Approach for Cancer Treatment. 2021 Oct 28 2
2 33137555 Discovery of novel sulfonamide-containing aminophosphonate derivatives as selective COX-2 inhibitors and anti-tumor candidates. 2020 Dec 2
3 31052167 Dihydropyrazole Derivatives Containing Benzo Oxygen Heterocycle and Sulfonamide Moieties Selectively and Potently Inhibit COX-2: Design, Synthesis, and Anti-Colon Cancer Activity Evaluation. 2019 Apr 30 3
4 27272369 [«Sulfonamide allergy» - which drugs must patients avoid?]. 2016 Jun 1
5 22341941 Novel 5-substituted 1H-tetrazoles as cyclooxygenase-2 (COX-2) inhibitors. 2012 Mar 15 2
6 15702813 Tolerance of nonsteroidal anti-inflammatory drug-sensitive patients to the highly specific cyclooxygenase 2 inhibitors rofecoxib and valdecoxib. 2005 Jan 1
7 15318279 Acute generalized exanthematous pustulosis caused by celecoxib. 2004 Jul 1
8 15324885 Exploring QSAR with E-state index: selectivity requirements for COX-2 versus COX-1 binding of terphenyl methyl sulfones and sulfonamides. 2004 Sep 20 3
9 15369392 Novel synthesis of 3,4-diarylisoxazole analogues of valdecoxib: reversal cyclooxygenase-2 selectivity by sulfonamide group removal. 2004 Sep 23 1
10 14604691 Design and synthesis of novel celecoxib analogues as selective cyclooxygenase-2 (COX-2) inhibitors: replacement of the sulfonamide pharmacophore by a sulfonylazide bioisostere. 2003 Nov 17 1
11 12013363 Celecoxib-induced erythema multiforme with glyburide cross-reactivity. 2002 May 1
12 11330653 Should celecoxib be contraindicated in patients who are allergic to sulfonamides? Revisiting the meaning of 'sulfa' allergy. 2001 1
13 11520213 Design and synthesis of celecoxib and rofecoxib analogues as selective cyclooxygenase-2 (COX-2) inhibitors: replacement of sulfonamide and methylsulfonyl pharmacophores by an azido bioisostere. 2001 Aug 30 1
14 9825305 Novel inhibitors of cyclooxygenase-2: the sulfones and sulfonamides of 1,2-diaryl-4,5-difluorobenzene. Analysis of quantitative structure-activity relationship. 1998 Sep 1
15 9135032 Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib). 1997 Apr 25 2
16 9171872 1,2-Diarylpyrroles as potent and selective inhibitors of cyclooxygenase-2. 1997 May 23 1
17 9351974 The interaction of arginine 106 of human prostaglandin G/H synthase-2 with inhibitors is not a universal component of inhibition mediated by nonsteroidal anti-inflammatory drugs. 1997 Nov 2