Flurbiprofen

prostaglandin-endoperoxide synthase 2 ; Homo sapiens







15 Article(s)
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1 27756840 Fatty Acid Binding to the Allosteric Subunit of Cyclooxygenase-2 Relieves a Tonic Inhibition of the Catalytic Subunit. 2016 Dec 2 1
2 22053353 (R)-Profens are substrate-selective inhibitors of endocannabinoid oxygenation by COX-2. 2011 Nov 1
3 19894761 Cyclooxygenase competitive inhibitors alter tyrosyl radical dynamics in prostaglandin H synthase-2. 2009 Dec 22 1
4 16606823 Partnering between monomers of cyclooxygenase-2 homodimers. 2006 Apr 18 4
5 12135387 Isoform-selective interaction of cyclooxygenase-2 with indomethacin amides studied by real-time fluorescence, inhibition kinetics, and site-directed mutagenesis. 2002 Jul 30 1
6 10977130 Flurbiprofen and enantiomers in ophthalmic solution tested as inhibitors of prostanoid synthesis in human blood. 2000 Aug 1
7 10977131 Constitutive cyclooxygenase-1 and induced cyclooxygenase-2 in isolated human iris inhibited by S(+) flurbiprofen. 2000 Aug 1
8 11006278 Arachidonic acid and nonsteroidal anti-inflammatory drugs induce conformational changes in the human prostaglandin endoperoxide H2 synthase-2 (cyclooxygenase-2). 2000 Dec 22 1
9 11095985 Cyclooxygenase-2 expression in lipopolysaccharide-stimulated human monocytes is modulated by cyclic AMP, prostaglandin E(2), and nonsteroidal anti-inflammatory drugs. 2000 Nov 30 2
10 10594327 Reactive oxygen species are involved in the apoptosis induced by nonsteroidal anti-inflammatory drugs in cultured gastric cells. 1999 Nov 3 1
11 9321948 Up-regulation of cyclooxygenase-2 by product-prostaglandin E2. 1997 1
12 9351974 The interaction of arginine 106 of human prostaglandin G/H synthase-2 with inhibitors is not a universal component of inhibition mediated by nonsteroidal anti-inflammatory drugs. 1997 Nov 1
13 8631960 The kinetic factors that determine the affinity and selectivity for slow binding inhibition of human prostaglandin H synthase 1 and 2 by indomethacin and flurbiprofen. 1996 Feb 16 3
14 8982652 Effects of flurbiprofen and flurbinitroxybutylester on prostaglandin endoperoxide synthases. 1996 Nov 28 1
15 7965814 Differential inhibition of human prostaglandin endoperoxide H synthases-1 and -2 by nonsteroidal anti-inflammatory drugs. 1994 Nov 2