15-deoxy-delta

peroxisome proliferator activated receptor gamma ; Homo sapiens







59 Article(s)
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1 32215785 Crosstalk Between Mast Cells and Adipocytes in Physiologic and Pathologic Conditions. 2020 Jun 1
2 25449421 Involvement of insulin-like growth factor binding protein-3 in peroxisome proliferator-activated receptor gamma-mediated inhibition of breast cancer cell growth. 2015 Jan 5 1
3 24337644 The 15-deoxy-δ12,14-prostaglandin J2 inhibits LPS‑stimulated inflammation via enhancement of the platelet‑activating factor acetylhydrolase activity in human retinal pigment epithelial cells. 2014 Feb 1
4 22469179 Activation of peroxisome proliferator-activated receptor γ prolongs islet allograft survival. 2012 1
5 22991494 Cytotoxicity of 15-deoxy-Δ(12,14)-prostaglandin J(2) through PPARγ-independent pathway and the involvement of the JNK and Akt pathway in renal cell carcinoma. 2012 2
6 21236332 15-Deoxy-Δ12,14-prostaglandin J2 induces Cox-2 expression in human osteosarcoma cells through MAPK and EGFR activation involving reactive oxygen species. 2011 Apr 1 1
7 21511917 15-Deoxy-delta12,14-prostaglandin J2-glycerol ester, a putative metabolite of 2-arachidonyl glycerol, activates peroxisome proliferator activated receptor gamma. 2011 Jul 1
8 21683069 15-Deoxy-Δ12,14-prostaglandin J2 enhanced the anti-tumor activity of camptothecin against renal cell carcinoma independently of topoisomerase-II and PPARγ pathways. 2011 Jul 8 1
9 20036328 Aldo-keto reductase 1C3 expression in MCF-7 cells reveals roles in steroid hormone and prostaglandin metabolism that may explain its over-expression in breast cancer. 2010 Feb 15 2
10 20438519 15-Deoxy-Delta12,14-prostaglandin J2 inhibits angiotensin II-induced fibronectin expression via hepatocyte growth factor induction in human peritoneal mesothelial cells. 2010 Feb 2
11 20670683 The nitric oxide-donating pravastatin, NCX 6550, inhibits cytokine release and NF-κB activation while enhancing PPARγ expression in human monocyte/macrophages. 2010 Nov 1
12 20843793 Thiazolidinediones up-regulate insulin-like growth factor-1 receptor via a peroxisome proliferator-activated receptor gamma-independent pathway. 2010 Nov 19 3
13 18983509 15-deoxy-Delta12,14 prostaglandin J2-induced heme oxygenase-1 in megakaryocytes regulates thrombopoiesis. 2009 Jan 2
14 19018984 Elevated concentrations of 15-deoxy-Delta12,14-prostaglandin J2 in chronic liver disease propose therapeutic trials with peroxisome proliferator activated receptor gamma-inducing drugs. 2009 May 2
15 19101554 Atomic structure of mutant PPARgamma LBD complexed with 15d-PGJ2: novel modulation mechanism of PPARgamma/RXRalpha function by covalently bound ligands. 2009 Jan 22 3
16 19275963 Selective, potent PPARgamma agonists with cyclopentenone core structure. 2009 Apr 1 1
17 19286977 Electrophilic peroxisome proliferator-activated receptor-gamma ligands have potent antifibrotic effects in human lung fibroblasts. 2009 Dec 1
18 19346435 Thiazolidinediones induce proliferation of human bronchial epithelial cells through the GPR40 receptor. 2009 Jun 2
19 19673929 Peroxisome proliferator-activated receptor gamma-independent effects of thiazolidinediones on human cardiac myofibroblast function. 2009 May 1
20 18535203 Sepsis-induced inhibition of neutrophil chemotaxis is mediated by activation of peroxisome proliferator-activated receptor-{gamma}. 2008 Nov 15 2
21 18615183 The PPAR-gamma Agonist 15-Deoxy-Delta-Prostaglandin J(2) Attenuates Microglial Production of IL-12 Family Cytokines: Potential Relevance to Alzheimer's Disease. 2008 1
22 17707368 15-Deoxy-delta(12,14)-prostaglandin J(2) down-regulates CXCR4 on carcinoma cells through PPARgamma- and NFkappaB-mediated pathways. 2007 Oct 1 1
23 16310861 Positioning prostanoids of the D and J series in the immunopathogenic scheme. 2006 Feb 15 3
24 16386710 Niacin induces PPARgamma expression and transcriptional activation in macrophages via HM74 and HM74a-mediated induction of prostaglandin synthesis pathways. 2006 Feb 28 1
25 16484546 Nuclear receptors and autoimmune disease: the potential of PPAR agonists to treat multiple sclerosis. 2006 Mar 2
26 16601291 Peroxisome proliferator-activated receptor gamma in human breast carcinoma: a modulator of estrogenic actions. 2006 Mar 2
27 15531761 Differential regulation of chemokine expression by peroxisome proliferator-activated receptor gamma agonists: interactions with glucocorticoids and beta2-agonists. 2005 Jan 28 1
28 16000871 15-Deoxy-delta12,14-PGJ2 inhibits IL-6-induced Stat3 phosphorylation in lymphocytes. 2005 Jun 30 1
29 16020752 Peroxisome proliferator-activated receptor gamma ligands stimulate endothelial nitric oxide production through distinct peroxisome proliferator-activated receptor gamma-dependent mechanisms. 2005 Sep 2
30 16077033 15-deoxy-Delta12,14 prostaglandin J2 up-regulates Kruppel-like factor 4 expression independently of peroxisome proliferator-activated receptor gamma by activating the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signal transduction pathway in HT-29 colon cancer cells. 2005 Nov 2
31 16253239 ET-18-O-CH3-induced apoptosis is causally linked to COX-2 upregulation in H-ras transformed human breast epithelial cells. 2005 Nov 7 2
32 15023995 Activation of peroxisome proliferator-activated receptor gamma inhibits interleukin-1beta-induced membrane-associated prostaglandin E2 synthase-1 expression in human synovial fibroblasts by interfering with Egr-1. 2004 May 21 1
33 12524224 Peroxisome proliferator-activated receptor gamma ligands increase release of nitric oxide from endothelial cells. 2003 Jan 1 2
34 12604364 15-Deoxy-Delta(12,14)-prostaglandin J2 inhibits the expression of proinflammatory genes in human blood monocytes via a PPAR-gamma-independent mechanism. 2003 Mar 7 1
35 12759491 15-deoxy-delta(12,14)-prostaglandin J2 inhibits IFN-gamma-induced galectin-9 expression in cultured human umbilical vein endothelial cells. 2003 May 2
36 12847270 Inhibition of IFN-gamma-mediated inducible nitric oxide synthase induction by the peroxisome proliferator-activated receptor gamma agonist, 15-deoxy-delta 12,14-prostaglandin J2, involves inhibition of the upstream Janus kinase/STAT1 signaling pathway. 2003 Jul 15 1
37 14515149 Prostaglandin-J(2) upregulates expression of matrix metalloproteinase-1 independently of activation of peroxisome proliferator-activated receptor-gamma. 2003 1
38 14555212 Peroxisome proliferator-activated receptor gamma (PPARgamma) ligands as bifunctional regulators of cell proliferation. 2003 Oct 15 1
39 14580366 Effect of 15-deoxy-delta12,14-prostaglandin J2 on IL-1beta-induced expression of epithelial neutrophil-activating protein-78 in human endothelial cells. 2003 Nov 2
40 14607914 Cyclopentenone prostaglandins induce lymphocyte apoptosis by activating the mitochondrial apoptosis pathway independent of external death receptor signaling. 2003 Nov 15 3
41 11872377 Roles of peroxisome proliferator-activated receptor gamma in cardiovascular disease. 2002 Jan-Feb 1
42 11950812 Characteristics of the peroxisome proliferator activated receptor gamma (PPARgamma) ligand induced apoptosis in colon cancer cells. 2002 May 1
43 11973610 Ligand activation of peroxisome proliferator-activated receptor gamma induces apoptosis of leukemia cells by down-regulating the c-myc gene expression via blockade of the Tcf-4 activity. 2002 May 1
44 11987982 Human B lymphocytes and B lymphomas express PPAR-gamma and are killed by PPAR-gamma agonists. 2002 Apr 1
45 12065695 Nonsteroidal anti-inflammatory drugs induce apoptosis in association with activation of peroxisome proliferator-activated receptor gamma in rheumatoid synovial cells. 2002 Jul 1
46 12269390 Apoptosis induced by activation of peroxisome-proliferator activated receptor-gamma is associated with Bcl-2 and NF-kappaB in human colon cancer. 2002 Apr 19 2
47 12454768 15-PGJ2, but not thiazolidinediones, inhibits cell growth, induces apoptosis, and causes downregulation of Stat3 in human oral SCCa cells. 2002 Dec 2 1
48 11159824 Albumin regulates induction of peroxisome proliferator-activated receptor-gamma (PPARgamma) by 15-deoxy-delta(12-14)-prostaglandin J(2) in vitro and may be an important regulator of PPARgamma function in vivo. 2001 Feb 4
49 11278336 Peroxisome proliferator-activated receptor gamma ligands suppress the transcriptional activation of cyclooxygenase-2. Evidence for involvement of activator protein-1 and CREB-binding protein/p300. 2001 Apr 13 2
50 11278956 Peroxisome proliferator-activated receptor-gamma activation inhibits interleukin-1beta -mediated platelet-derived growth factor-alpha receptor gene expression via CCAAT/enhancer-binding protein-delta in vascular smooth muscle cells. 2001 Apr 20 1