9 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 24731275 | Design, syntheses, and characterization of piperazine based chemokine receptor CCR5 antagonists as anti prostate cancer agents. | 2014 May 15 | 1 |
2 | 23308267 | Design, synthesis and biological evaluation of novel piperazine derivatives as CCR5 antagonists. | 2013 | 1 |
3 | 20347189 | Efficient synthesis and identification of novel propane-1,3-diamino bridged CCR5 antagonists with variation on the basic center carrier. | 2010 Jul | 1 |
4 | 18019544 | Forward- and reverse-synthesis of piperazinopiperidine amide analogs: a general access to structurally diverse 4-piperazinopiperidine-based CCR5 antagonists. | 2007 Aug 21 | 2 |
5 | 15115380 | Piperazine-based CCR5 antagonists as HIV-1 inhibitors. IV. Discovery of 1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]- 4-[4-[2-methoxy-1(R)-4-(trifluoromethyl)phenyl]ethyl-3(S)-methyl-1-piperazinyl]- 4-methylpiperidine (Sch-417690/Sch-D), a potent, highly selective, and orally bioavailable CCR5 antagonist. | 2004 May 6 | 1 |
6 | 15203141 | Facile synthesis of 4-substituted-4-aminopiperidine derivatives, the key building block of piperazine-based CCR5 antagonists. | 2004 Jul 16 | 1 |
7 | 14521412 | Generation of predictive pharmacophore models for CCR5 antagonists: study with piperidine- and piperazine-based compounds as a new class of HIV-1 entry inhibitors. | 2003 Oct 9 | 2 |
8 | 11514156 | Piperazine-based CCR5 antagonists as HIV-1 inhibitors. I: 2(S)-methyl piperazine as a key pharmacophore element. | 2001 Aug 20 | 1 |
9 | 11585438 | Piperazine-based CCR5 antagonists as HIV-1 inhibitors. II. Discovery of 1-[(2,4-dimethyl-3-pyridinyl)carbonyl]-4- methyl-4-[3(S)-methyl-4-[1(S)-[4-(trifluoromethyl)phenyl]ethyl]-1-piperazinyl]- piperidine N1-oxide (Sch-350634), an orally bioavailable, potent CCR5 antagonist. | 2001 Oct 11 | 2 |