alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide

Janus kinase 2 ; Homo sapiens







187 Article(s)
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1 34859389 IL-27 Mediates Th1 Cells Infiltration in Fetal Membranes in Preterm Labor. 2022 Jun 1
2 35216134 Ginsenoside Rh4 Suppressed Metastasis of Lung Adenocarcinoma via Inhibiting JAK2/STAT3 Signaling. 2022 Feb 11 1
3 35475417 Angiotensin-converting enzyme 2 inhibits inflammation and apoptosis in high glucose-stimulated microvascular endothelial cell damage by regulating the JAK2/STAT3 signaling pathway. 2022 Apr 1
4 33037575 Folic Acid Deficiency Enhances the Tyr705 and Ser727 Phosphorylation of Mitochondrial STAT3 in In Vivo and In Vitro Models of Ischemic Stroke. 2021 Oct 1
5 33807148 Shikonin Derivatives from Onsoma visianii Decrease Expression of Phosphorylated STAT3 in Leukemia Cells and Exert Antitumor Activity. 2021 Mar 31 1
6 33855026 Inhibition of JAK-STAT Signaling Pathway Alleviates Age-Related Phenotypes in Tendon Stem/Progenitor Cells. 2021 1
7 34584986 Blockade of JAK2 signaling produces immunomodulatory effect to preserve pancreatic homeostasis in severe acute pancreatitis. 2021 Dec 2
8 34627931 Thymoquinone induces oxidative stress-mediated apoptosis through downregulation of Jak2/STAT3 signaling pathway in human melanoma cells. 2021 Nov 2
9 34691358 THAP9-AS1 Promotes Tumorigenesis and Reduces ROS Generation through the JAK2/STAT3 Signaling Pathway by Increasing SOCS3 Promoter Methylation in Osteosarcoma. 2021 1
10 34970139 Yi Shen Juan Bi Pill Regulates the Bone Immune Microenvironment via the JAK2/STAT3 Signaling Pathway in Vitro. 2021 2
11 31948746 Liraglutide promotes the angiogenic ability of human umbilical vein endothelial cells through the JAK2/STAT3 signaling pathway. 2020 Mar 12 1
12 32059851 Epidermal growth factor alleviates cerebral ischemia-induced brain injury by regulating expression of neutrophil gelatinase-associated lipocalin. 2020 Apr 16 1
13 32338270 Lysine inhibits apoptosis in satellite cells to govern skeletal muscle growth via the JAK2-STAT3 pathway. 2020 May 1 1
14 32377718 The JAK2/STAT3 pathway inhibitor, AG490, suppresses the abnormal behavior of keloid fibroblasts in vitro. 2020 Jul 3
15 32392199 [Inhibition of Non-Receptor Tyrosine Kinase JAK2 Reduces Neuroblastoma Cell Growth and Enhances the Action of Doxorubicin]. 2020 Mar-Apr 1
16 32647179 Tensile force-induced PDGF-BB/PDGFRβ signals in periodontal ligament fibroblasts activate JAK2/STAT3 for orthodontic tooth movement. 2020 Jul 9 1
17 32793721 Cancer-associated fibroblasts promote the migration and invasion of gastric cancer cells via activating IL-17a/JAK2/STAT3 signaling. 2020 Jul 3
18 32841893 Induction of proliferative and mutagenic activity by benzo(a)pyrene in PC-3 cells via JAK2/STAT3 pathway. 2020 May - Dec 1
19 32945388 Phosphorylation of STAT3 and ERBB2 mediates hypoxia‑induced VEGF release in ARPE‑19 cells. 2020 Oct 1
20 30654529 AZD1208, a Pan-Pim Kinase Inhibitor, Has Anti-Growth Effect on 93T449 Human Liposarcoma Cells via Control of the Expression and Phosphorylation of Pim-3, mTOR, 4EBP-1, S6, STAT-3 and AMPK. 2019 Jan 16 1
21 30706361 Combination of MEK Inhibitor and the JAK2-STAT3 Pathway Inhibition for the Therapy of Colon Cancer. 2019 Apr 2
22 30785507 The effect of hirudin on antagonisting thrombin induced apoptosis of human microvascular endothelial cells1. 2019 Feb 14 1
23 31234944 Epiregulin reprograms cancer-associated fibroblasts and facilitates oral squamous cell carcinoma invasion via JAK2-STAT3 pathway. 2019 Jun 24 2
24 28782829 The participation of fibroblast growth factor 23 (FGF23) in the progression of osteoporosis via JAK/STAT pathway. 2018 May 1
25 28822039 Stimulation of nAchRα7 Receptor Inhibits TNF Synthesis and Secretion in Response to LPS Treatment of Mast Cells by Targeting ERK1/2 and TACE Activation. 2018 Mar 1
26 29215754 Inhibition of JAK2/STAT3 reduces tumor-induced angiogenesis and myeloid-derived suppressor cells in head and neck cancer. 2018 Mar 1
27 29423056 Role of ZNF224 in c-Myc repression and imatinib responsiveness in chronic myeloid leukemia. 2018 Jan 9 1
28 29441020 Eriodictyol Attenuates Myocardial Ischemia-Reperfusion Injury through the Activation of JAK2. 2018 1
29 29477470 α-Hederin inhibits interleukin 6-induced epithelial-to-mesenchymal transition associated with disruption of JAK2/STAT3 signaling in colon cancer cells. 2018 May 1
30 29487013 AG490, a JAK2-specific inhibitor, downregulates the expression and activity of organic anion transporter-3. 2018 Mar 2
31 29565447 CAFs enhance paclitaxel resistance by inducing EMT through the IL‑6/JAK2/STAT3 pathway. 2018 May 1
32 29934528 GRAMD1B regulates cell migration in breast cancer cells through JAK/STAT and Akt signaling. 2018 Jun 22 1
33 30013646 Pachymic acid inhibits growth and induces cell cycle arrest and apoptosis in gastric cancer SGC-7901 cells. 2018 Aug 1
34 30157477 Dipeptide (Methionyl-Methionine) Transport and Its Effect on β-Casein Synthesis in Bovine Mammary Epithelial Cells. 2018 1
35 30209718 Specific effects of neuregulin-1β on the communication between DRG neurons and skeletal muscle cells in vitro. 2018 Aug 1
36 30341486 Berberine-Promoted CXCR4 Expression Accelerates Endothelial Repair Capacity of Early Endothelial Progenitor Cells in Persons with Prehypertension. 2018 Dec 1
37 30405790 Ganoderic acid A exerts antitumor activity against MDA-MB-231 human breast cancer cells by inhibiting the Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway. 2018 Nov 1
38 30416690 The JAK2V617F Point Mutation Increases the Osteoclast Forming Ability of Monocytes in Patients with Chronic Myeloproliferative Neoplasms and Makes their Osteoclasts more Susceptible to JAK2 Inhibition. 2018 1
39 30523225 [Effect of AG490 on JAK2/STAT3 signaling pathway in human retinoblastoma HXO-RB44 cell lines]. 2018 Oct 28 1
40 30584711 [IFN-γ induces overexpression of PD-L1 and epithelialmesenchymal transformation of breast cancer cells through activating ERK/Jak2-STAT signaling pathways]. 2018 Dec 25 3
41 31949699 Exogenous H2S promotes cancer progression by activating JAK2/STAT3 signaling pathway in esophageal EC109 cells. 2018 1
42 27611607 Leptin Is Produced by Parathyroid Glands and Stimulates Parathyroid Hormone Secretion. 2017 Dec 1
43 28177455 JAK-STAT signaling mediates the senescence of bone marrow-mesenchymal stem cells from systemic lupus erythematosus patients. 2017 Mar 1 1
44 28296539 High salt-induced activation and expression of inflammatory cytokines in cultured astrocytes. 2017 Apr 18 3
45 28337870 JAK2 tyrosine kinase inhibitor AG490 suppresses cell growth and invasion of gallbladder cancer cells via inhibition of JAK2/STAT3 signaling. 2017 Jan-Mar 3
46 28732559 SOCS-1 is involved in TNF-α-induced mitochondrial dysfunction and apoptosis in renal tubular epithelial cells. 2017 Oct 1
47 28765891 Non-coding RNA 886 promotes renal cell carcinoma growth and metastasis through the Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway. 2017 Oct 1
48 28827891 JAK2/STAT3 Pathway Was Associated with the Protective Effects of IL-22 On Aortic Dissection with Acute Lung Injury. 2017 1
49 28881584 Dimerization of EGFR and HER2 induces breast cancer cell motility through STAT1-dependent ACTA2 induction. 2017 Aug 1 1
50 28901435 Differential regulation by IFN‑γ on TNF‑α‑induced chemokine expression in synovial fibroblasts from temporomandibular joint. 2017 Nov 1