Etoposide

MDM2 proto-oncogene ; Homo sapiens







19 Article(s)
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1 34572735 Chemotherapy of HER2- and MDM2-Enriched Breast Cancer Subtypes Induces Homologous Recombination DNA Repair and Chemoresistance. 2021 Sep 7 1
2 30532073 MDM2-mediated degradation of WRN promotes cellular senescence in a p53-independent manner. 2019 Apr 1
3 28196907 Acetylation-dependent regulation of MDM2 E3 ligase activity dictates its oncogenic function. 2017 Feb 14 1
4 28692049 Mdm2 selectively suppresses DNA damage arising from inhibition of topoisomerase II independent of p53. 2017 Nov 2 1
5 28959361 Effect of etoposide-induced alteration of the Mdm2-Rb signaling pathway on cellular senescence in A549 lung adenocarcinoma cells. 2017 Oct 3
6 25954860 Low expression of phosphatase and tensin homolog in clear‑cell renal cell carcinoma contributes to chemoresistance through activating the Akt/HDM2 signaling pathway. 2015 Aug 1
7 23318437 Knockdown of RNF2 induces apoptosis by regulating MDM2 and p53 stability. 2014 Jan 23 1
8 24486906 A plausible model for bimodal p53 switch in DNA damage response. 2014 Mar 3 1
9 24732641 MDM2 rs2279744 and TP53 rs1042522 polymorphisms associated with etoposide- and cisplatin-induced grade III/IV neutropenia in Chinese extensive-stage small-cell lung cancer patients. 2014 1
10 18096571 Mdm2 as a sensitive and mechanistically informative marker for genotoxicity induced by benzo[a]pyrene and dibenzo[a,l]pyrene. 2008 Apr 1
11 15908423 A chromatin-associated and transcriptionally inactive p53-Mdm2 complex occurs in mdm2 SNP309 homozygous cells. 2005 Jul 22 1
12 16093994 Differential regulation of p21waf-1/cip-1 and Mdm2 by etoposide: etoposide inhibits the p53-Mdm2 autoregulatory feedback loop. 2005 Sep 4
13 11125034 MDM2 mediated nuclear exclusion of p53 attenuates etoposide-induced apoptosis in neuroblastoma cells. 2001 Jan 3
14 11306736 The levels of MDM2 protein are decreased by a proteasome-mediated proteolysis prior to caspase-3-dependent pRb and PARP cleavages. 2001 Apr 2
15 11393276 Additive effect of adenovirus-mediated E2F-1 gene transfer and topoisomerase II inhibitors on apoptosis in human osteosarcoma cells. 2001 Apr 2
16 11742497 High levels of the MDM2 oncogene in paediatric rhabdomyosarcoma cell lines may confer multidrug resistance. 2001 Nov 30 1
17 10023685 Differential regulation of p21waf-1/cip-1 and Mdm2 by etoposide: etoposide inhibits the p53-Mdm2 autoregulatory feedback loop. 1999 Jan 28 8
18 10544021 Activation of p53 in MDM2-overexpressing cells through phosphorylation. 1999 Nov 2 2
19 8883415 mdm2 gene mediates the expression of mdr1 gene and P-glycoprotein in a human glioblastoma cell line. 1996 Oct 2