Azathioprine

nudix hydrolase 15 ; Homo sapiens







38 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 32842934 A rare case of Azathioprine-induced leukopenia in an European woman. 2022 Feb 1
2 34582038 TPMT and NUDT15 Variants Predict Discontinuation of Azathioprine for Myelotoxicity in Patients with Inflammatory Disease: Real-World Clinical Results. 2022 Jan 5
3 34751173 A novel NUDT15 variant identified in Caucasian TPMT wild type patients with inflammatory bowel disease and azathioprine-related myelotoxicity. 2022 Jan 1 1
4 34866237 Effect of NUDT15 polymorphisms on early hematological safety of low-dose azathioprine in Chinese patients with pemphigus vulgaris: A prospective cohort study. 2022 Apr 3
5 35118815 Predicted expression of genes involved in the thiopurine metabolic pathway and azathioprine discontinuation due to myelotoxicity. 2022 Apr 4
6 32617765 Precision medicine for rheumatologists: lessons from the pharmacogenomics of azathioprine. 2021 Jan 2
7 33707905 Thiopurine-induced Myelosuppression with Severe Sepsis in a Patient with Crohn's Disease: A Case Report. 2021 Feb 2
8 33846471 Association of genetic variants in TPMT, ITPA, and NUDT15 with azathioprine-induced myelosuppression in southwest china patients with autoimmune hepatitis. 2021 Apr 12 3
9 33860754 Importance of NUDT15 c.415C>T phenotype in treatment of inflammatory bowel disease with azathioprine and occurrence of severe myelosuppression: A case report. 2021 Jul 2
10 33950972 Azathioprine-induced toxoplasma gondii infection in a patient with Crohn's disease with NUDT15 variation: A case report. 2021 May 7 4
11 34084143 Association Between Genetic Polymorphisms of Metabolic Enzymes and Azathioprine-Induced Myelosuppression in 1,419 Chinese Patients: A Retrospective Study. 2021 4
12 34430579 Cost-effectiveness analysis of genotype screening and therapeutic drug monitoring in patients with inflammatory bowel disease treated with azathioprine therapy: a Chinese healthcare perspective using real-world data. 2021 Jul 4
13 34466252 Azathioprine-induced severe myelosuppression accompanied by massive hair loss and painful oral ulcer in an autoimmune hepatitis patient with NUDT15 minor variant: A case report. 2021 Aug 2
14 31744310 First Case of Azathioprine-Induced Severe Hematotoxicity in a Tunisian Patient With Homozygous TT for NUDT15 rs116855232. 2020 May 1
15 32062783 Predictive Value of NUDT15 Variants on Neutropenia Among Han Chinese Patients with Dermatologic Diseases: A Single-Center Observational Study. 2020 Apr 2
16 32187056 Association of thiopurine S-methyltransferase and NUDT15 polymorphisms with azathioprine-induced myelotoxicity in Chinese patients with rheumatological disease. 2020 Apr 20 1
17 32598049 Adjustment of azathioprine dose should be based on a lower 6-TGN target level to avoid leucopenia in NUDT15 intermediate metabolisers. 2020 Aug 3
18 32713039 Complete remission of refractory pemphigus vulgaris in a Chinese patient with mutated NUDT15 by combination of minimal doses of azathioprine and prednisone. 2020 Nov 3
19 32827393 NUDT15 polymorphism explains serious toxicity to azathioprine in Indian patients with chronic immune thrombocytopenia and autoimmune hemolytic anemia: a case series. 2020 Aug 24 1
20 33111378 NUDT15 C415T variant compared with TPMT genotyping in predicting azathioprine-induced leucopenia: prospective analysis of 1014 inflammatory bowel disease patients in India. 2020 Dec 3
21 33442476 NUDT15 genotyping during azathioprine treatment in patients with inflammatory bowel disease: implications for a dose-optimization strategy. 2020 Dec 3
22 30035323 Azathioprine-induced myelosuppression in two pemphigus vulgaris patients with homozygous polymorphism of NUDT15. 2019 Feb 1
23 30742971 Novel multiple heterozygous NUDT15 variants cause an azathioprine-induced severe leukopenia in a patient with systemic lupus erythematosus. 2019 Mar 1
24 30843183 NUDT15 polymorphism identified in a patient with azathioprine hypersensitivity syndrome presenting as erythema nodosum and hepatotoxicity. 2019 Sep 1
25 31024313 NUDT15 Polymorphism Confer Increased Susceptibility to Thiopurine-Induced Leukopenia in Patients With Autoimmune Hepatitis and Related Cirrhosis. 2019 3
26 31556692 NUDT15 and TPMT Genetic Polymorphisms Are Related to Azathioprine Intolerance in Chinese Patients with Rheumatic Diseases. 2019 Oct 3
27 29491687 Comparison of TPMT and NUDT15 polymorphisms in Chinese patients with inflammatory bowel disease. 2018 Feb 28 4
28 29702976 NUDT15 R139C variation increases the risk of azathioprine-induced toxicity in Chinese subjects: Case report and literature review. 2018 Apr 4
29 29704867 Azathioprine-induced alopecia and leukopenia associated with NUDT15 polymorphisms. 2018 Oct 1
30 29867468 NUDT15 R139C Variants Increase the Risk of Azathioprine-Induced Leukopenia in Chinese Autoimmune Patients. 2018 4
31 30101994 Severe thiopurine-induced leukocytopenia and hair loss in Japanese patients with defective NUDT15 variant: Retrospective case-control study. 2018 Oct 2
32 30106365 Neutropenia related to an azathioprine metabolic disorder induced by an inosine triphosphate pyrophosphohydrolase (ITPA) gene mutation in a patient with PR3-ANCA-positive microscopic polyangiitis
. 2018 Nov 1
33 30577288 Azathioprine-induced Agranulocytosis and Severe Alopecia After Kidney Transplantation Associated With a NUDT15 Polymorphism: A Case Report. 2018 Dec 3
34 28566182 NUDT15 p.R139C variant is common and strongly associated with azathioprine-induced early leukopenia and severe alopecia in Korean patients with various neurological diseases. 2017 Jul 15 3
35 28670229 NUDT15, FTO, and RUNX1 genetic variants and thiopurine intolerance among Japanese patients with inflammatory bowel diseases. 2017 Jul 1
36 26735160 NUDT15 variant is the most common variant associated with thiopurine-induced early leukopenia and alopecia in Korean pediatric patients with Crohn's disease. 2016 Apr 1
37 26935390 Thiopurine Biotransformation and Pharmacological Effects: Contribution of Oxidative Stress. 2016 1
38 27381176 Further evidence that a variant of the gene NUDT15 may be an important predictor of azathioprine-induced toxicity in Chinese subjects: a case report. 2016 Oct 3