Epoprostenol

prostaglandin-endoperoxide synthase 2 ; Rattus norvegicus







27 Article(s)
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1 34491608 Chronic mercury exposure induces oxidative stress in female rats by endothelial nitric oxide synthase uncoupling and cyclooxygenase-2 activation, without affecting oestrogen receptor function. 2021 Dec 1
2 30710549 Mechanisms underlying vascular hypocontractility induced by ethanol withdrawal: Role of cyclooxygenase 2-derived prostacyclin. 2019 Mar 15 1
3 27803479 Analysis of Vascular Cell Response to Hypertension Induced by Pressure Loading and Its Application as a Tool for Exploring Pharmacological Modes of Action. 2016 1
4 25761067 Early co-expression of cyclooxygenase-2 and renin in the rat kidney cortex contributes to the development of N(G)-nitro-L-arginine methyl ester induced hypertension. 2015 Apr 1
5 23586845 Periodontitis increases vascular cyclooxygenase-2: potential effect on vascular tone. 2014 Feb 2
6 25388440 Time course change of COX2-PGI2/TXA2 following global cerebral ischemia reperfusion injury in rat hippocampus. 2014 Nov 11 1
7 22975359 NS-398 reverses hypotension in endotoxemic rats: contribution of eicosanoids, NO, and peroxynitrite. 2013 Jul-Aug 2
8 23276664 COX-2-derived prostaglandins do not contribute to coronary flow regulation in diabetic rats: distinct secretion patterns of PGI2 and PGE2. 2013 Jan 30 1
9 23524072 Cyclooxygenase-2-derived prostanoids reduce inward arterial remodeling induced by blood flow reduction in old obese Zucker rat mesenteric arteries. 2013 May-Jun 2
10 22155309 Ozone induces synthesis of systemic prostacyclin by cyclooxygenase-2 dependent mechanism in vivo. 2012 Feb 15 1
11 18500359 Aldosterone induces endothelial dysfunction in resistance arteries from normotensive and hypertensive rats by increasing thromboxane A2 and prostacyclin. 2008 Jul 1
12 16754782 Inhibition of proinflammatory tumor necrosis factor-{alpha}-induced inducible nitric-oxide synthase by xanthine-based 7-[2-[4-(2-chlorobenzene)piperazinyl]ethyl]-1,3-dimethylxanthine (KMUP-1) and 7-[2-[4-(4-nitrobenzene)piperazinyl]ethyl]-1, 3-dimethylxanthine (KMUP-3) in rat trachea: The involvement of soluble guanylate cyclase and protein kinase G. 2006 Sep 1
13 15525649 Angiotensin II and epidermal growth factor induce cyclooxygenase-2 expression in intestinal epithelial cells through small GTPases using distinct signaling pathways. 2005 Jan 14 2
14 15855806 Different effect of cyclosporine A and mycophenolate mofetil on passive Heymann nephritis in the rat. 2005 1
15 14757118 Cerivastatin inhibits proliferation of interleukin-1 beta-induced rat mesangial cells by enhanced formation of nitric oxide. 2004 Feb 6 1
16 15521009 Up-regulation of the enzymes involved in prostacyclin synthesis via Ras induces vascular endothelial growth factor. 2004 Nov 1
17 12623302 Role of cyclooxygenase 2, p38 and p42/44 MAPK in the secretion of prostacyclin induced by epidermal growth factor, endothelin-1 and angiotensin II in rat ventricular cardiomyocytes. 2003 Jan 1
18 12967932 Early upregulation of kinin B1 receptors in retinal microvessels of the streptozotocin-diabetic rat. 2003 Sep 1
19 14613874 Prostacyclin production in rat aortic smooth muscle cells: role of protein kinase C, phospholipase D and cyclooxygenase-2 expression. 2003 Nov 1 3
20 14629650 Effects of IL-1beta, TNF-alpha, and macrophage migration inhibitory factor on prostacyclin synthesis in rat pulmonary artery smooth muscle cells. 2003 Dec 2
21 12036946 Peroxisome proliferator-activated receptors modulate K-Ras-mediated transformation of intestinal epithelial cells. 2002 Jun 1 1
22 12388283 COX-2-derived prostacyclin mediates opioid-induced late phase of preconditioning in isolated rat hearts. 2002 Dec 1
23 11518732 Inhibition of cyclooxygenase-2 aggravates doxorubicin-mediated cardiac injury in vivo. 2001 Aug 1
24 11672585 Daunorubicin inhibits gene expression of cyclooxygenase-2 in vascular smooth muscle cells. 2001 Aug 1 1
25 10688636 Effects of selective and unselective cyclooxygenase inhibitors on prostanoid release from various rat organs. 2000 Mar 2
26 9182946 Up-regulation of cyclooxygenase-2 expression in cultured microglia by prostaglandin E2, cyclic AMP and non-steroidal anti-inflammatory drugs. 1997 May 1
27 8967523 Effects of acute and chronic hypoxia on rat lung cyclooxygenase. 1996 May 2