N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide

prostaglandin-endoperoxide synthase 2 ; Rattus norvegicus







132 Article(s)
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1 33671779 Vitamin D Deficiency Cause Gender Specific Alterations of Renal Arterial Function in a Rodent Model. 2021 Feb 22 1
2 33488395 Chronic Low-Level Lead Exposure Increases Mesenteric Vascular Reactivity: Role of Cyclooxygenase-2-Derived Prostanoids. 2020 1
3 27815021 Interleukin-1β induces sleep independent of prostaglandin D2 in rats and mice. 2017 Jan 6 2
4 28522561 Immediate and delayed potentiating effects of tumor necrosis factor-α on TRPV1 sensitivity of rat vagal pulmonary sensory neurons. 2017 Aug 1 2
5 26463949 Cyclooxygenase-2 Inhibition Provides Lasting Protection Following Germinal Matrix Hemorrhage in Premature Infant Rats. 2016 1
6 26685759 Low-salt diet increases NO bioavailability and COX-2 vasoconstrictor prostanoid production in spontaneously hypertensive rats. 2016 Jan 15 2
7 27795807 Cox-2 Inhibition Protects against Hypoxia/Reoxygenation-Induced Cardiomyocyte Apoptosis via Akt-Dependent Enhancement of iNOS Expression. 2016 1
8 25453777 Co-administration of subtherapeutic diazepam enhances neuroprotective effect of COX-2 inhibitor, NS-398, after lithium pilocarpine-induced status epilepticus. 2015 Jan 22 3
9 26735056 Enhanced cyclooxygenase-2 activity leads to intestinal dysmotility following hemorrhagic shock. 2015 Dec 1
10 24500985 Effects of all-trans retinoic acid on signal pathway of cyclooxygenase-2 and Smad3 in transforming growth factor-β-stimulated glomerular mesangial cells. 2014 Mar 1
11 24548897 Induction of heme oxygenase-1 ameliorates vascular dysfunction in streptozotocin-induced type 2 diabetic rats. 2014 Apr 1
12 24621600 Brain interleukin-1β and the intrinsic receptor antagonist control peripheral Toll-like receptor 3-mediated suppression of spontaneous activity in rats. 2014 1
13 25324681 ERK1/2/COX-2/PGE2 signaling pathway mediates GPR91-dependent VEGF release in streptozotocin-induced diabetes. 2014 2
14 22349912 The cyclooxygenase-2 selective inhibitor NS-398 does not influence trabecular or cortical bone gain resulting from repeated mechanical loading in female mice. 2013 Jan 2
15 22975359 NS-398 reverses hypotension in endotoxemic rats: contribution of eicosanoids, NO, and peroxynitrite. 2013 Jul-Aug 2
16 23276663 Rosuvastatin inhibits pressure-induced fibrotic responses via the expression regulation of prostacyclin and prostaglandin E2 in rat renal tubular cells. 2013 Jan 30 2
17 23276664 COX-2-derived prostaglandins do not contribute to coronary flow regulation in diabetic rats: distinct secretion patterns of PGI2 and PGE2. 2013 Jan 30 1
18 23874545 COX-2-derived prostanoids and oxidative stress additionally reduce endothelium-mediated relaxation in old type 2 diabetic rats. 2013 1
19 22489918 Mechano-transcription of COX-2 is a common response to lumen dilation of the rat gastrointestinal tract. 2012 Jul 1
20 22713546 Long-term leptin treatment exerts a pro-apoptotic effect on renal tubular cells via prostaglandin E2 augmentation. 2012 Aug 15 2
21 22995181 JAK-STAT pathway modulates the roles of iNOS and COX-2 in the cytoprotection of early phase of hydrogen peroxide preconditioning against apoptosis induced by oxidative stress. 2012 Nov 7 2
22 23029388 Interaction between lysophosphatidic acid, prostaglandins and the endocannabinoid system during the window of implantation in the rat uterus. 2012 1
23 21051526 Pathophysiology of motility dysfunction in bowel obstruction: role of stretch-induced COX-2. 2011 Jan 1
24 21164135 Cyclooxygenase-2 mediates hyperbaric oxygen preconditioning in the rat model of transient global cerebral ischemia. 2011 Feb 1
25 21527272 Evidence that PGE2 in the dorsal and median raphe nuclei is involved in LPS-induced anorexia in rats. 2011 Sep 1
26 21734275 Pyramidal neurons are "neurogenic hubs" in the neurovascular coupling response to whisker stimulation. 2011 Jul 6 1
27 21927668 Proliferation of Hepatic Oval Cells via Cyclooxygenase-2 and Extracellular Matrix Protein Signaling during Liver Regeneration Following 2-AAF/Partial Hepatectomy in Rats. 2011 Sep 2
28 19786037 COX-2 inhibition controls P-glycoprotein expression and promotes brain delivery of phenytoin in chronic epileptic rats. 2010 Feb 1
29 20027123 Centrally administered lipopolysaccharide elicits sympathetic excitation via NAD(P)H oxidase-dependent mitogen-activated protein kinase signaling. 2010 Apr 1
30 20032084 Cyclooxygenase-2 preserves flow-mediated remodelling in old obese Zucker rat mesenteric arteries. 2010 Jun 1 1
31 20091889 Increased COX2 in the trigeminal nucleus caudalis is involved in orofacial pain induced by experimental tooth movement. 2010 Mar 1
32 20826536 Prostaglandin F2α (PGF2α) stimulates PTGS2 expression and PGF2α synthesis through NFKB activation via reactive oxygen species in the corpus luteum of pseudopregnant rats. 2010 Dec 1
33 21423385 Cyclooxygenase-2 inhibition restored endothelium-mediated relaxation in old obese zucker rat mesenteric arteries. 2010 1
34 22545970 Contribution of vasoactive eicosanoids and nitric oxide production to the effect of selective cyclooxygenase-2 inhibitor, NS-398, on endotoxin-induced hypotension in rats. 2010 Nov 1
35 18522674 Effects of chronic celecoxib on testicular function in normal and lipopolysaccharide-treated rats. 2009 Oct 1
36 19145780 p38 MAPK contributes to angiotensin II-induced COX-2 expression in aortic fibroblasts from normotensive and hypertensive rats. 2009 Jan 1
37 19297370 Helium-induced late preconditioning in the rat heart in vivo. 2009 May 1
38 19371577 Prevention of seizure-induced up-regulation of endothelial P-glycoprotein by COX-2 inhibition. 2009 Apr 1
39 19467272 Effect of cyclooxygenase-2 on the regulation of cerebral blood flow during neuronal activation in the rat. 2009 Sep 1
40 19672123 PGE2 causes mesangial cell hypertrophy and decreases expression of cyclin D3. 2009 1
41 19765729 COX-2 inhibition improves immune system homeostasis and decreases liver damage in septic rats. 2009 Nov 3
42 17901979 Cyclooxygenase-2 mediates the delayed cardioprotection induced by hydrogen sulfide preconditioning in isolated rat cardiomyocytes. 2008 Mar 1
43 18048500 Expression and biological activity of parathyroid hormone-related peptide in pregnant rat uterine artery: any role for 8-iso-prostaglandin F2alpha? 2008 Feb 1
44 18988310 Cyclooxygenase-2 inhibitor inhibits hippocampal synaptic reorganization in pilocarpine-induced status epilepticus rats. 2008 Nov 2
45 19020121 Xenon induces late cardiac preconditioning in vivo: a role for cyclooxygenase 2? 2008 Dec 1
46 17169358 Participation of CGRP and prostanoids in the sex-linked differences of vascular anandamide effects in mesenteric beds of Sprague-Dawley rats. 2007 Feb 14 1
47 17251525 Constitutive expression of prostaglandin-endoperoxide synthase 2 by somatic and spermatogenic cells is responsible for prostaglandin E2 production in the adult rat testis. 2007 May 2
48 16441783 Cyclooxygenase-2 inhibition selectively attenuates bone morphogenetic protein-6 synthesis and bone formation during guided tissue regeneration in a rat model. 2006 Feb 1
49 16540558 Cyclooxygenase-2 rescues rat mesangial cells from apoptosis induced by adriamycin via upregulation of multidrug resistance protein 1 (P-glycoprotein). 2006 Apr 1
50 16572115 Transforming growth factor beta regulates cyclooxygenase-2 in glomerular mesangial cells. 2006 May 4