Dinoprostone

prostaglandin-endoperoxide synthase 2 ; Rattus norvegicus







185 Article(s)
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51 23404506 EP2 receptor signaling pathways regulate classical activation of microglia. 2013 Mar 29 1
52 23652412 Anti-inflammatory effects of essential oils from Chamaecyparis obtusa via the cyclooxygenase-2 pathway in rats. 2013 Jul 1
53 23790320 Lysophosphatidic acid increases the production of pivotal mediators of decidualization and vascularization in the rat uterus. 2013 Sep 2
54 23799821 Treatment with SiMiaoFang, an anti-arthritis chinese herbal formula, inhibits cartilage matrix degradation in osteoarthritis rat model. 2013 Oct 1
55 23818898 The ETS-Domain Transcription Factor Elk-1 Regulates COX-2 Gene Expression and Inhibits Glucose-Stimulated Insulin Secretion in the Pancreatic β -Cell Line INS-1. 2013 3
56 24136226 The inhibition of 2-arachidonoyl-glycerol (2-AG) biosynthesis, rather than enhancing striatal damage, protects striatal neurons from malonate-induced death: a potential role of cyclooxygenase-2-dependent metabolism of 2-AG. 2013 Oct 17 1
57 22089194 Paeonol attenuates microglia-mediated inflammation and oxidative stress-induced neurotoxicity in rat primary microglia and cortical neurons. 2012 Mar 1
58 22165968 Characterization of the prostaglandin E2 pathway in a rat model of esophageal adenocarcinoma. 2012 Feb 4
59 22519838 Targeting pain mediators induced by injured nerve-derived COX2 and PGE2 to treat neuropathic pain. 2012 Jun 1
60 22713546 Long-term leptin treatment exerts a pro-apoptotic effect on renal tubular cells via prostaglandin E2 augmentation. 2012 Aug 15 2
61 22959208 The cyclooxygenase-2 inhibitor parecoxib inhibits surgery-induced proinflammatory cytokine expression in the hippocampus in aged rats. 2012 Nov 1
62 23029388 Interaction between lysophosphatidic acid, prostaglandins and the endocannabinoid system during the window of implantation in the rat uterus. 2012 2
63 21328464 Delayed production of arachidonic acid contributes to the delay of proteinase-activated receptor-1 (PAR1)-triggered prostaglandin E2 release in rat gastric epithelial RGM1 cells. 2011 Mar 1
64 21371033 Role of prostaglandin E2 in the synthesis of the pro-inflammatory cytokine interleukin-6 in primary sensory neurons: an in vivo and in vitro study. 2011 Sep 1
65 21527272 Evidence that PGE2 in the dorsal and median raphe nuclei is involved in LPS-induced anorexia in rats. 2011 Sep 4
66 21873648 SO(2)-induced neurotoxicity is mediated by cyclooxygenases-2-derived prostaglandin E(2) and its downstream signaling pathway in rat hippocampal neurons. 2011 Dec 1
67 18786748 Injured nerve-derived COX2/PGE2 contributes to the maintenance of neuropathic pain in aged rats. 2010 Jul 1
68 20027123 Centrally administered lipopolysaccharide elicits sympathetic excitation via NAD(P)H oxidase-dependent mitogen-activated protein kinase signaling. 2010 Apr 1
69 20142564 Brain perivascular macrophages and the sympathetic response to inflammation in rats after myocardial infarction. 2010 Mar 1
70 18522674 Effects of chronic celecoxib on testicular function in normal and lipopolysaccharide-treated rats. 2009 Oct 1
71 19145780 p38 MAPK contributes to angiotensin II-induced COX-2 expression in aortic fibroblasts from normotensive and hypertensive rats. 2009 Jan 1
72 19352545 Protective effects of DIDS against ethanol-induced gastric mucosal injury in rats. 2009 Apr 1
73 19583997 Transcriptional regulation of iNOS and COX-2 by a novel compound from Curcuma comosa in lipopolysaccharide-induced microglial activation. 2009 Sep 22 2
74 19679653 Inhibition of cyclooxygenase-2 down-regulates aromatase activity and decreases proliferation of Leydig tumor cells. 2009 Oct 16 3
75 19826189 Involvement of cyclooxygenase 2 and prostagladin E(2) in the effects of insulin on gastric emptying in male rats. 2009 Sep 1
76 18174279 Systemic immune challenge activates an intrinsically regulated local inflammatory circuit in the adrenal gland. 2008 Apr 1
77 18183617 Retinoic acid enhances prostaglandin E2 production through increased expression of cyclooxygenase-2 and microsomal prostaglandin E synthase-1 in rat brain microglia. 2008 May 1 1
78 18297109 Prostaglandin E2 glycerol ester, an endogenous COX-2 metabolite of 2-arachidonoylglycerol, induces hyperalgesia and modulates NFkappaB activity. 2008 Apr 1
79 18481165 Selective increase of neuronal cyclooxygenase-2 (COX-2) expression in vulnerable brain regions of rats with experimental Wernicke's encephalopathy: effect of nimesulide. 2008 Jun 2
80 18567640 The PGE2-Stat3 interaction in doxorubicin-induced myocardial apoptosis. 2008 Oct 1 2
81 18782027 Lead compounds for anti-inflammatory drugs isolated from the plants of the traditional oriental medicine in Korea. 2008 Sep 4
82 17234396 Decreased tumor growth in Walker 256 tumor-bearing rats chronically supplemented with fish oil involves COX-2 and PGE2 reduction associated with apoptosis and increased peroxidation. 2007 Feb 1
83 17251525 Constitutive expression of prostaglandin-endoperoxide synthase 2 by somatic and spermatogenic cells is responsible for prostaglandin E2 production in the adult rat testis. 2007 May 1
84 17505916 Several transcription factors regulate COX-2 gene expression in pancreatic beta-cells. 2007 Sep 3
85 17537981 Selective COX-2 inhibition markedly slows disease progression and attenuates altered prostanoid production in Han:SPRD-cy rats with inherited kidney disease. 2007 Sep 1
86 17704286 The cardioprotection of the late phase of ischemic preconditioning is enhanced by postconditioning via a COX-2-mediated mechanism in conscious rats. 2007 Oct 1
87 17868147 PGE(2) receptor EP1 renders dopaminergic neurons selectively vulnerable to low-level oxidative stress and direct PGE(2) neurotoxicity. 2007 Nov 1 2
88 17943254 Prostaglandin E2 stimulates VEGF expression in primary rat gastric fibroblasts through EP4 receptors. 2007 Oct 2
89 24459504 Dysregulation of Renal Cyclooxygenase-2 in Rats with Lithium-induced Nephrogenic Diabetes Insipidus. 2007 Dec 4
90 16210398 Roles of cyclooxygenase 2 and microsomal prostaglandin E synthase 1 in rat acid reflux oesophagitis. 2006 Apr 2
91 16309709 Prostaglandin E2 deteriorates N-methyl-D-aspartate receptor-mediated cytotoxicity possibly by activating EP2 receptors in cultured cortical neurons. 2006 Mar 13 1
92 16322109 A selective COX-2 inhibitor suppresses chronic pancreatitis in an animal model (WBN/Kob rats): significant reduction of macrophage infiltration and fibrosis. 2006 Aug 1
93 16427196 Peripheral inflammation modifies the effect of intrathecal IL-1beta on spinal PGE2 production mainly through cyclooxygenase-2 activity. A spinal microdialysis study in freely moving rats. 2006 Feb 1
94 16580130 The long-term exposure of rat cultured dorsal root ganglion cells to bradykinin induced the release of prostaglandin E2 by the activation of cyclooxygenase-2. 2006 Jul 3 1
95 16616432 Facilitation of spike-wave discharge activity by lipopolysaccharides in Wistar Albino Glaxo/Rijswijk rats. 2006 Jun 30 1
96 16680021 The response of neonatal rat ventricular myocytes to lipopolysaccharide-induced stress. 2006 May 1
97 16754782 Inhibition of proinflammatory tumor necrosis factor-{alpha}-induced inducible nitric-oxide synthase by xanthine-based 7-[2-[4-(2-chlorobenzene)piperazinyl]ethyl]-1,3-dimethylxanthine (KMUP-1) and 7-[2-[4-(4-nitrobenzene)piperazinyl]ethyl]-1, 3-dimethylxanthine (KMUP-3) in rat trachea: The involvement of soluble guanylate cyclase and protein kinase G. 2006 Sep 1
98 16809483 Circulating interleukin-6 induces fever through a STAT3-linked activation of COX-2 in the brain. 2006 Nov 1
99 16912428 Effect of peroxisome proliferator activated receptor (PPAR)gamma agonists on prostaglandins cascade in joint cells. 2006 2
100 17331331 Anti-inflammatory activity of the synthetic C-C biflavonoids. 2006 Dec 1