Prostaglandins

prostaglandin-endoperoxide synthase 2 ; Rattus norvegicus







189 Article(s)
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1 34920958 Protectin DX promotes the inflammatory resolution via activating COX-2/L-PGDS-PGD2 and DP1 receptor in acute respiratory distress syndrome. 2022 Jan 1
2 35172004 Metabolic Profiling Implicates a Critical Role of Cyclooxygenase-2-Mediated Arachidonic Acid Metabolism in Radiation-Induced Esophageal Injury in Rats. 2022 May 1 2
3 31622656 Experimental sepsis-associated encephalopathy is accompanied by altered cerebral blood perfusion and water diffusion and related to changes in cyclooxygenase-2 expression and glial cell morphology but not to blood-brain barrier breakdown. 2020 Jan 1
4 30528878 Bradykinin and interleukin-1β synergistically increase the expression of cyclooxygenase-2 through the RNA-binding protein HuR in rat dorsal root ganglion cells. 2019 Feb 16 2
5 31161614 Cellular and physiological upregulation of inducible nitric oxide synthase, arginase, and inducible cyclooxygenase in wound healing. 2019 Dec 2
6 31417487 COX-2 Inhibition by Diclofenac Is Associated With Decreased Apoptosis and Lesion Area After Experimental Focal Penetrating Traumatic Brain Injury in Rats. 2019 2
7 29306822 Celecoxib, a cyclooxygenase-2 inhibitor, offers chemoprevention against reproductive and neurobehavioural abnormalities induced by atrazine in male Wistar rats. 2018 Mar 1
8 29425800 Influence of the selective COX-2 inhibitor celecoxib on sex differences in blood pressure and albuminuria in spontaneously hypertensive rats. 2018 Mar 2
9 27815021 Interleukin-1β induces sleep independent of prostaglandin D2 in rats and mice. 2017 Jan 6 2
10 28556994 Hyperglycaemia in pregnant rats causes sex-related vascular dysfunction in adult offspring: role of cyclooxygenase-2. 2017 Aug 1 2
11 29201221 Leptin upregulates COX-2 and its downstream products in aortic endothelial cells. 2017 Nov 3
12 26685759 Low-salt diet increases NO bioavailability and COX-2 vasoconstrictor prostanoid production in spontaneously hypertensive rats. 2016 Jan 15 1
13 26935999 TRPA1-dependent regulation of bladder detrusor smooth muscle contractility in normal and type I diabetic rats. 2016 1
14 27351941 Treatment with high dose of atorvastatin reduces vascular injury in diabetic rats. 2016 Oct 1
15 27803479 Analysis of Vascular Cell Response to Hypertension Induced by Pressure Loading and Its Application as a Tool for Exploring Pharmacological Modes of Action. 2016 1
16 27834752 Cyclooxygenase-2-Derived Prostaglandins Mediate Cerebral Microcirculation in a Juvenile Ischemic Rat Model. 2016 Dec 1
17 26335727 Anandamide and decidual remodelling: COX-2 oxidative metabolism as a key regulator. 2015 Nov 2
18 24647712 Postnatal regulation of 15-hydroxyprostaglandin dehydrogenase in the rat kidney. 2014 Aug 15 2
19 25388440 Time course change of COX2-PGI2/TXA2 following global cerebral ischemia reperfusion injury in rat hippocampus. 2014 Nov 11 3
20 22572003 Lactobacillus casei cell wall extract directly stimulates the expression of COX2 independent of Toll-like receptor 2 in rat glial cells. 2013 Oct 2
21 22975359 NS-398 reverses hypotension in endotoxemic rats: contribution of eicosanoids, NO, and peroxynitrite. 2013 Jul-Aug 2
22 23184385 Angiotensin II-independent upregulation of cyclooxygenase-2 by activation of the (Pro)renin receptor in rat renal inner medullary cells. 2013 Feb 2
23 23276664 COX-2-derived prostaglandins do not contribute to coronary flow regulation in diabetic rats: distinct secretion patterns of PGI2 and PGE2. 2013 Jan 30 3
24 23624225 COX2-derived primary and cyclopentenone prostaglandins are increased after asphyxial cardiac arrest. 2013 Jun 26 5
25 23661609 A novel function for CUGBP2 in controlling the pro-inflammatory stimulus in H9c2 cells: subcellular trafficking of messenger molecules. 2013 Oct 4
26 23790320 Lysophosphatidic acid increases the production of pivotal mediators of decidualization and vascularization in the rat uterus. 2013 Sep 1
27 23874545 COX-2-derived prostanoids and oxidative stress additionally reduce endothelium-mediated relaxation in old type 2 diabetic rats. 2013 1
28 22131058 Immunodetection of cyclooxygenase-2 (COX-2) is restricted to tissue macrophages in normal rat liver and to recruited mononuclear phagocytes in liver injury and cholangiocarcinoma. 2012 Feb 2
29 22554772 Cyclooxygenase-2 prostaglandins mediate anandamide-inhibitory action on nitric oxide synthase activity in the receptive rat uterus. 2012 Jun 15 3
30 22578329 Autocatalytic nitration of prostaglandin endoperoxide synthase-2 by nitrite inhibits prostanoid formation in rat alveolar macrophages. 2012 Nov 15 1
31 22971439 Activation of kinin B1 receptor evokes hyperthermia through a vagal sensory mechanism in the rat. 2012 Sep 13 1
32 21527272 Evidence that PGE2 in the dorsal and median raphe nuclei is involved in LPS-induced anorexia in rats. 2011 Sep 3
33 21734275 Pyramidal neurons are "neurogenic hubs" in the neurovascular coupling response to whisker stimulation. 2011 Jul 6 1
34 21873648 SO(2)-induced neurotoxicity is mediated by cyclooxygenases-2-derived prostaglandin E(2) and its downstream signaling pathway in rat hippocampal neurons. 2011 Dec 1
35 21885043 The gene encoding cyclooxygenase-2 is regulated by IL-1β and prostaglandins in 832/13 rat insulinoma cells. 2011 2
36 22004922 Parthenolide attenuates LPS-induced fever, circulating cytokines and markers of brain inflammation in rats. 2011 Dec 2
37 22174936 TTF-1 action on the transcriptional regulation of cyclooxygenase-2 gene in the rat brain. 2011 2
38 19660237 Effect of COX-2 inhibitor meloxicam against traumatic brain injury-induced biochemical, histopathological changes and blood-brain barrier permeability. 2010 Jul 2
39 19789943 Effects of selective Cox-2 inhibitor, rofecoxib, alone or combination with furosemide on renal functions and renal Cox-2 expression in rats. 2010 Feb 1
40 20032084 Cyclooxygenase-2 preserves flow-mediated remodelling in old obese Zucker rat mesenteric arteries. 2010 Jun 1 1
41 20228412 The role of cyclooxygenase (COX)-2 derived prostanoids on vasoconstrictor responses to phenylephrine is increased by exposure to low mercury concentration. 2010 Feb 3
42 20353773 The COX-2 inhibitor parecoxib is neuroprotective but not antiepileptogenic in the pilocarpine model of temporal lobe epilepsy. 2010 Jul 2
43 20534845 Early life activation of toll-like receptor 4 reprograms neural anti-inflammatory pathways. 2010 Jun 9 3
44 20600289 Soman increases neuronal COX-2 levels: possible link between seizures and protracted neuronal damage. 2010 Dec 3
45 20688085 Cox-2 inhibition attenuates cardiovascular and inflammatory aspects in monosodium glutamate-induced obese rats. 2010 Sep 11 1
46 20956003 Enhanced cyclooxygenase 2-mediated vasorelaxation in coronary arteries from insulin-resistant obese Zucker rats. 2010 Dec 1
47 21423385 Cyclooxygenase-2 inhibition restored endothelium-mediated relaxation in old obese zucker rat mesenteric arteries. 2010 3
48 18522674 Effects of chronic celecoxib on testicular function in normal and lipopolysaccharide-treated rats. 2009 Oct 1
49 19007904 Celecoxib exacerbates hepatic fibrosis and induces hepatocellular necrosis in rats treated with porcine serum. 2009 Apr 2
50 19194550 Effects of celecoxib and nordihydroguaiaretic acid on puromycin aminonucleoside-induced nephrosis in the rat. 2009 Jan 2