Glucose

mitogen-activated protein kinase 3 ; Mus musculus







59 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34859931 DR1 activation promotes vascular smooth muscle cell apoptosis via up-regulation of CSE/H2 S pathway in diabetic mice. 2022 Jan 1
2 34865281 CDK5 inhibition improves glucose uptake in insulin-resistant neuronal cells via ERK1/2 pathway. 2022 Mar 1
3 35173145 Heparanase promotes endothelial-to-mesenchymal transition in diabetic glomerular endothelial cells through mediating ERK signaling. 2022 Feb 16 1
4 35281932 Dapagliflozin Reduces Apoptosis of Diabetic Retina and Human Retinal Microvascular Endothelial Cells Through ERK1/2/cPLA2/AA/ROS Pathway Independent of Hypoglycemic. 2022 1
5 35513431 FGF21-FGFR4 signaling in cardiac myocytes promotes concentric cardiac hypertrophy in mouse models of diabetes. 2022 May 5 1
6 34053181 Cardiac metallothionein overexpression rescues diabetic cardiomyopathy in Akt2-knockout mice. 2021 Jul 1
7 34179020 Endothelial Aryl Hydrocarbon Receptor Nuclear Translocator Mediates the Angiogenic Response to Peripheral Ischemia in Mice With Type 2 Diabetes Mellitus. 2021 1
8 34518608 Ketamine ameliorates depressive-like behaviors in mice through increasing glucose uptake regulated by the ERK/GLUT3 signaling pathway. 2021 Sep 13 3
9 31899483 A protective role of renalase in diabetic nephropathy. 2020 Jan 17 1
10 32512010 High glucose-induced ROS accumulation is a critical regulator of ERK1/2-Akt-tuberin-mTOR signalling in RGC-5 cells. 2020 Sep 1 1
11 32945406 Different MAPK signal transduction pathways play different roles in the impairment of glucose‑stimulated insulin secretion in response to IL‑1β. 2020 Oct 1
12 30597356 Natural flavonoid galangin alleviates microglia-trigged blood-retinal barrier dysfunction during the development of diabetic retinopathy. 2019 Mar 1
13 31040360 Heterogeneous Nuclear Ribonucleoprotein F Mediates Insulin Inhibition of Bcl2-Modifying Factor Expression and Tubulopathy in Diabetic Kidney. 2019 Apr 30 1
14 31365278 Erianin alleviates diabetic retinopathy by reducing retinal inflammation initiated by microglial cells via inhibiting hyperglycemia-mediated ERK1/2-NF-κB signaling pathway. 2019 Nov 1
15 31755338 Regulation of dendritic cell function by A20 through high glucose-induced Akt2 signaling. 2019 Oct-Dec 1
16 29018002 Glucose uptake inhibition decreases expressions of receptor activator of nuclear factor-kappa B ligand (RANKL) and osteocalcin in osteocytic MLO-Y4-A2 cells. 2018 Feb 1 1
17 30352794 Chromomycin A2 potently inhibits glucose-stimulated insulin secretion from pancreatic β cells. 2018 Dec 3 1
18 27975141 Glucose and angiotensin II-derived endothelial extracellular vesicles regulate endothelial dysfunction via ERK1/2 activation. 2017 Feb 4
19 28190775 DRP1 Suppresses Leptin and Glucose Sensing of POMC Neurons. 2017 Mar 7 1
20 28433068 The role of interleukin-1β and extracellular signal-regulated kinase 1/2 in glucose-stimulated insulin secretion. 2017 May 4
21 28721437 ERK1 is dispensable for mouse pancreatic beta cell function but is necessary for glucose-induced full activation of MSK1 and CREB. 2017 Oct 6
22 28947919 Glucagon-like peptide-1 receptor agonist exendin-4 protects against interleukin-1β-mediated inhibition of glucose-stimulated insulin secretion by mouse insulinoma β cells. 2017 Sep 2
23 27035884 Role of extracellular signal‑regulated kinase 1/2 signal transduction pathway in insulin secretion by β‑TC6 cells. 2016 May 3
24 27095850 Secretagogin affects insulin secretion in pancreatic β-cells by regulating actin dynamics and focal adhesion. 2016 Jun 15 1
25 27488452 Resveratrol inhibits renal interstitial fibrosis in diabetic nephropathy by regulating AMPK/NOX4/ROS pathway. 2016 Dec 2
26 27498780 Effects of linagliptin and liraglutide on glucose- and angiotensin II-induced collagen formation and cytoskeleton degradation in cardiac fibroblasts in vitro. 2016 Sep 2
27 24885625 High glucose increases LPS-induced DC apoptosis through modulation of ERK1/2, AKT and Bax/Bcl-2. 2014 May 28 1
28 25133193 Tribbles 3 regulates the fibrosis cytokine TGF- β 1 through ERK1/2-MAPK signaling pathway in diabetic nephropathy. 2014 1
29 23344729 The permissive effects of glucose on receptor-operated potentiation of insulin secretion from mouse islets: a role for ERK1/2 activation and cytoskeletal remodelling. 2013 Apr 4
30 23379999 Inhibition of high glucose-induced VEGF release in retinal ganglion cells by RNA interference targeting G protein-coupled receptor 91. 2013 Apr 2
31 23428406 Diastereomeric mixture of calophyllic acid and isocalophyllic acid stimulates glucose uptake in skeletal muscle cells: involvement of PI-3-kinase- and ERK1/2-dependent pathways. 2013 May 6 2
32 23766264 PKCβ promotes vascular inflammation and acceleration of atherosclerosis in diabetic ApoE null mice. 2013 Aug 1
33 23942551 Inhibition of Src kinase blocks high glucose-induced EGFR transactivation and collagen synthesis in mesangial cells and prevents diabetic nephropathy in mice. 2013 Nov 1
34 22139838 Novel mechanistic link between focal adhesion remodeling and glucose-stimulated insulin secretion. 2012 Jan 20 4
35 22800886 LRP16 gene protects mouse insulinoma MIN6 cells against fatty acid-induced apoptosis through Akt/FoxO1 signaling. 2012 May 1
36 20953578 Deficiency in the extracellular signal-regulated kinase 1 (ERK1) protects leptin-deficient mice from insulin resistance without affecting obesity. 2011 Jan 2
37 21099329 Pim3 negatively regulates glucose-stimulated insulin secretion. 2010 Sep-Oct 5
38 19091959 Sphingosine-1-phosphate inhibits high glucose-mediated ERK1/2 action in endothelium through induction of MAP kinase phosphatase-3. 2009 Feb 2
39 19500499 [Losartan inhibits high glucose-induced CTGF expression via ERK1/2 MAPK pathways in mouse mesangial cells]. 2009 Jun 6
40 19502418 Involvement of Per-Arnt-Sim Kinase and extracellular-regulated kinases-1/2 in palmitate inhibition of insulin gene expression in pancreatic beta-cells. 2009 Sep 1
41 17962352 Mechanisms of glucose-induced expression of pancreatic-derived factor in pancreatic beta-cells. 2008 Feb 2
42 18456735 Microvessel vascular smooth muscle cells contribute to collagen type I deposition through ERK1/2 MAP kinase, alphavbeta3-integrin, and TGF-beta1 in response to ANG II and high glucose. 2008 Jul 1
43 17198096 Activations of nPKCepsilon and ERK1/2 were involved in oxygen-glucose deprivation-induced neuroprotection via NMDA receptors in hippocampal slices of mice. 2007 Jan 1
44 17440593 [High glucose downregulates the expression of podocalyxin protein in glomerular podocytes of mice]. 2007 Apr 18 4
45 16396989 Differential mitogenic signaling in insulin receptor-deficient fetal pancreatic beta-cells. 2006 Apr 1
46 16487264 High glucose-induced inhibition of 2-deoxyglucose uptake is mediated by cAMP, protein kinase C, oxidative stress and mitogen-activated protein kinases in mouse embryonic stem cells. 2006 Mar 1
47 16638805 Regulation of pancreatic beta-cell insulin secretion by actin cytoskeleton remodelling: role of gelsolin and cooperation with the MAPK signalling pathway. 2006 May 15 1
48 16778968 [High glucose regulates the expression of connective tissue growth factor and its receptor (low density lipoprotein receptor-related protein) in cultured podocytes]. 2006 Jun 18 4
49 16873684 ERK1/2 control phosphorylation and protein level of cAMP-responsive element-binding protein: a key role in glucose-mediated pancreatic beta-cell survival. 2006 Aug 6
50 16985513 Reactive oxygen species and nuclear factor-kappa B pathway mediate high glucose-induced Pax-2 gene expression in mouse embryonic mesenchymal epithelial cells and kidney explants. 2006 Nov 2