Arsenic Trioxide

caspase 3 ; Homo sapiens







87 Article(s)
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51 17956674 [Mechanisms underlying the effect of arsenic trioxide on proliferation inhibition and apoptosis induction in myeloma cell line u266]. 2007 Oct 2
52 16685442 Combination treatment with arsenic trioxide and sulindac augments their apoptotic potential in lung cancer cells through activation of caspase cascade and mitochondrial dysfunction. 2006 Jun 1
53 15637062 PRAM-1 potentiates arsenic trioxide-induced JNK activation. 2005 Mar 11 3
54 15665116 Pharmacologic inhibitors of PI3K/Akt potentiate the apoptotic action of the antileukemic drug arsenic trioxide via glutathione depletion and increased peroxide accumulation in myeloid leukemia cells. 2005 May 15 1
55 15979894 Arsenic trioxide overcomes apoptosis inhibition in K562/ADM cells by regulating vital components in apoptotic pathway. 2005 Nov 1
56 16010437 Arsenic trioxide mediates intrinsic and extrinsic pathways of apoptosis and cell cycle arrest in acute megakaryocytic leukemia. 2005 Aug 1
57 16051535 As2O3 enhances the anion transport activity of band 3 and the action is related with the C-terminal 16 residues of the protein. 2005 May 1
58 15493360 Arsenic trioxide causes redistribution of cell cycle, caspase activation, and GADD expression in human colonic, breast, and pancreatic cancer cells. 2004 1
59 12750841 Arsenic trioxide induces apoptosis in cells of MOLT-4 and its daunorubicin-resistant cell line via depletion of intracellular glutathione, disruption of mitochondrial membrane potential and activation of caspase-3. 2003 Jul 2
60 12754411 Arsenic trioxide-induced apoptosis is independent of stress-responsive signaling pathways but sensitive to inhibition of inducible nitric oxide synthase in HepG2 cells. 2003 Apr 30 2
61 12760770 [Investigation of apoptosis mechanism of arsenic trioxide on oral squamous cell carcinoma]. 2003 Jan 1
62 12883267 Arsenic trioxide induces apoptosis in pancreatic cancer cells via changes in cell cycle, caspase activation, and GADD expression. 2003 Aug 2
63 12931215 Sustained activation of c-jun-terminal kinase (JNK) is closely related to arsenic trioxide-induced apoptosis in an acute myeloid leukemia (M2)-derived cell line, NKM-1. 2003 Nov 1
64 12963972 Tetraarsenic oxide induces apoptosis in U937 leukemic cells through a reactive oxygen species-dependent pathway. 2003 Oct 2
65 14559676 Arsenic trioxide-induced apoptosis of human malignant lymphoma cell lines and its mechanisms. 2003 Oct 2
66 14632209 Arsenic trioxide induces apoptosis of cutaneous T cell lymphoma cells: evidence for a partially caspase-independent pathway and potentiation by ascorbic acid (vitamin C). 2003 Oct 1
67 14668793 Arsenic enhances the activation of Stat1 by interferon gamma leading to synergistic expression of IRF-1. 2003 Dec 11 1
68 11866444 Arsenic trioxide-induced apoptosis and its enhancement by buthionine sulfoximine in hepatocellular carcinoma cell lines. 2002 Mar 8 1
69 12005185 Arsenic trioxide-induced apoptosis through oxidative stress in cells of colon cancer cell lines. 2002 Mar 29 1
70 12023044 Enhancement of radiation response in human cervical cancer cells in vitro and in vivo by arsenic trioxide (As2O3). 2002 May 22 1
71 12034346 Effect of arsenic trioxide on human hepatocellular carcinoma HepG2 cells: inhibition of proliferation and induction of apoptosis. 2002 Jun 7 1
72 12063550 Arsenic trioxide induces apoptosis through a reactive oxygen species-dependent pathway and loss of mitochondrial membrane potential in HeLa cells. 2002 Jul 2
73 12148893 Arsenic trioxide induces apoptosis in HTLV-I infected T-cell lines and fresh adult T-cell leukemia cells through CD95 or tumor necrosis factor alpha receptor independent caspase activation. 2002 May 1
74 12168106 Arsenic trioxide-induced apoptosis in U937 cells involve generation of reactive oxygen species and inhibition of Akt. 2002 Sep 2
75 12174905 Arsenic trioxide inhibits proliferation and induces apoptosis in pancreatic cancer cells. 2002 Jul-Aug 2
76 26680881 Arsenic Trioxide Induces Apoptosis of HL-60 Cells via Activation of Intrinsic Caspase Protease with Mitochondrial Dysfunction. 2002 Aug 1
77 11146441 Arsenic trioxide induces apoptosis in human gastric cancer cells through up-regulation of p53 and activation of caspase-3. 2001 Jan 15 1
78 11172589 Potential role of caspase-3 and -9 in arsenic trioxide-mediated apoptosis in PCI-1 head and neck cancer cells. 2001 Feb 2
79 11454688 Tumor growth inhibition by arsenic trioxide (As2O3) in the orthotopic metastasis model of androgen-independent prostate cancer. 2001 Jul 15 1
80 11520058 Arsenic trioxide induces G2/M growth arrest and apoptosis after caspase-3 activation and bcl-2 phosphorylation in promonocytic U937 cells. 2001 Aug 31 1
81 11739184 Arsenic trioxide induces apoptosis in human T-cell leukemia virus type 1- and type 2-infected cells by a caspase-3-dependent mechanism involving Bcl-2 cleavage. 2001 Dec 15 1
82 11779429 Arsenic trioxide induces multiple myeloma cell apoptosis via disruption of mitochondrial transmembrane potentials and activation of caspase-3. 2001 Jan 2
83 10673743 Arsenic trioxide-induced apoptosis and differentiation are associated respectively with mitochondrial transmembrane potential collapse and retinoic acid signaling pathways in acute promyelocytic leukemia. 2000 Feb 1
84 11021749 Involvement of CD95-independent caspase 8 activation in arsenic trioxide-induced apoptosis. 2000 Oct 1
85 10428472 Arsenic trioxide induces apoptosis in neuroblastoma cell lines through the activation of caspase 3 in vitro. 1999 Jul 16 2
86 10477740 Arsenic trioxide selectively induces acute promyelocytic leukemia cell apoptosis via a hydrogen peroxide-dependent pathway. 1999 Sep 15 1
87 9801394 Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide. 1998 Nov 5 2