Arsenic Trioxide

caspase 3 ; Homo sapiens







87 Article(s)
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1 31079498 Study of As2O3 regulating proliferation and apoptosis of Tca8113 cells by inhibiting the expression of Id-1. 2019 Dec 1
2 31257975 Arsenic trioxide and tetraarsenic oxide induce cytotoxicity and have a synergistic effect with cisplatin in paclitaxel-resistant ovarian cancer cells. 2019 Nov 2
3 29910624 Effects of the combination of As2O3 and AZT on proliferation inhibition and apoptosis induction of hepatoma HepG2 cells following silencing of Egr-1. 2018 1
4 30213730 The suppressive effect of arsenic trioxide on TET2-FOXP3-Lyn-Akt axis-modulated MCL1 expression induces apoptosis in human leukemia cells. 2018 Nov 1 1
5 30316766 Inhibition of PI3K signaling pathway enhances the chemosensitivity of APL cells to ATO: Proposing novel therapeutic potential for BKM120. 2018 Dec 15 1
6 30333888 Arsenic trioxide induces the apoptosis and decreases NF-κB expression in lymphoma cell lines. 2018 Nov 1
7 30343279 Novel Combination of Arsenic Trioxide (As2O3) Plus Resveratrol in Inducing Programmed Cell Death of Human Neuroblastoma SK-N-SH Cells. 2018 Nov-Dec 1
8 28823259 [Synergistic Killing Effects of Arsenic Trioxide Combined with Itraconazole on KG1a Cells]. 2017 Aug 1
9 28966729 Arsenic Trioxide Induces Apoptosis via Specific Signaling Pathways in HT-29 Colon Cancer Cells. 2017 Jan 1
10 29164574 Mechanism of As2O3 induces apoptosis of glioma U87 cells. 2017 Nov 1
11 25258189 Endoplasmic reticulum stress contributes to arsenic trioxide-induced intrinsic apoptosis in human umbilical and bone marrow mesenchymal stem cells. 2016 Mar 1
12 27592447 Osteoblasts activate the Nrf2 signalling pathway in response to arsenic trioxide treatment. 2016 Oct 2
13 26692822 Arsenic trioxide reduces chemo-resistance to 5-fluorouracil and cisplatin in HBx-HepG2 cells via complex mechanisms. 2015 1
14 24466103 Arsenic trioxide induces apoptosis in human platelets via C-Jun NH2-terminal kinase activation. 2014 1
15 24482137 Inactivation of Akt by arsenic trioxide induces cell death via mitochondrial-mediated apoptotic signaling in SGC-7901 human gastric cancer cells. 2014 Apr 1
16 24599717 Combined arsenic trioxide-cisplatin treatment enhances apoptosis in oral squamous cell carcinoma cells. 2014 Apr 1
17 24738333 Antitumor efficacy of DMSA modified Fe3O4 magnetic nanoparticles combined with arsenic trioxide and adriamycin in Raji cells. 2014 Feb 1
18 24815320 cAMP protects acute promyelocytic leukemia cells from arsenic trioxide-induced caspase-3 activation and apoptosis. 2014 Aug 5 1
19 24944602 Arsenic trioxide induces apoptosis in the THP1 cell line by downregulating EVI-1. 2014 Jul 3
20 25128771 Arsenic trioxide exerts a double effect on osteoblast growth in vitro. 2014 Sep 1
21 25415199 Downregulation of hTERT: an important As2O3 induced mechanism of apoptosis in myelodysplastic syndrome. 2014 2
22 23363563 Genistein ameliorates adverse cardiac effects induced by arsenic trioxide through preventing cardiomyocytes apoptosis. 2013 2
23 23373993 Arsenic trioxide induced apoptosis in retinoblastoma cells by abnormal expression of microRNA-376a. 2013 1
24 23404534 Arsenic trioxide-mediated oxidative stress and genotoxicity in human hepatocellular carcinoma cells. 2013 1
25 23645216 Azidothymidine hinders arsenic trioxide-induced apoptosis in acute promyelocytic leukemia cells by induction of p21 and attenuation of G2/M arrest. 2013 Sep 2
26 23980369 [Homoharringtonine combined arsenic trioxide induced apoptosis in human multiple myeloma cell line RPMI 8226: an experimental research]. 2013 Jun 2
27 24356076 MicroRNAs contribute to promyelocyte apoptosis in As2O3-treated APL cells. 2013 1
28 21826188 Synergistic Apoptosis-Inducing Antileukemic Effects of Arsenic Trioxide and Mucuna macrocarpa Stem Extract in Human Leukemic Cells via a Reactive Oxygen Species-Dependent Mechanism. 2012 1
29 22072212 Alteration in miRNA gene expression pattern in acute promyelocytic leukemia cell induced by arsenic trioxide: a possible mechanism to explain arsenic multi-target action. 2012 Feb 1
30 22391177 [Caspase-independent apoptosis induced by arsenic trioxide in human multiple myeloma cell RPMI8226]. 2012 Feb 1
31 22922937 Sulforaphane synergistically enhances the cytotoxicity of arsenic trioxide in multiple myeloma cells via stress-mediated pathways. 2012 Nov 1
32 22931643 [Effects of hyperbaric oxygenation combined with As(2)O(3) on proliferation of K562 cells and associated mechanism]. 2012 Aug 1
33 20799280 Arsenic trioxide induces apoptosis through JNK and ERK in human mesothelioma cells. 2011 Mar 4
34 21502917 Synergic effect of 3'-azido-3'-deoxythymidine and arsenic trioxide in suppressing hepatoma cells. 2011 Jun 1
35 21518486 [NB4 cell apoptosis induced by bortezomib combined with As(2)O(3) and its mechanism]. 2011 Apr 2
36 21655183 BIM-mediated AKT phosphorylation is a key modulator of arsenic trioxide-induced apoptosis in cisplatin-sensitive and -resistant ovarian cancer cells. 2011 2
37 21846841 Epoxyeicosatrienoic acids attenuate reactive oxygen species level, mitochondrial dysfunction, caspase activation, and apoptosis in carcinoma cells treated with arsenic trioxide. 2011 Nov 1
38 22977528 Arsenic trioxide induces the apoptosis of human breast cancer MCF-7 cells through activation of caspase-3 and inhibition of HERG channels. 2011 May 2
39 20454603 Arsenic Trioxide Modulates DNA Synthesis and Apoptosis in Lung Carcinoma Cells. 2010 May 1 1
40 20632473 Arsenic trioxide modulates DNA synthesis and apoptosis in lung carcinoma cells. 2010 May 1
41 20723293 [Effects of STI571 combined with As₂O₃ on proliferation, apoptosis and caspase 3, Bcl-xL expression of K562 cells]. 2010 Aug 2
42 20724260 Abrogating HSP response augments cell death induced by As2O3 in glioma cell lines. 2010 Jul 1
43 20796291 Basic mechanisms of arsenic trioxide (ATO)-induced apoptosis in human leukemia (HL-60) cells. 2010 Aug 26 1
44 19322013 Protein kinase C is involved in arsenic trioxide-induced apoptosis and inhibition of proliferation in human bladder cancer cells. 2009 1
45 19664237 Arsenic trioxide exerts synergistic effects with cisplatin on non-small cell lung cancer cells via apoptosis induction. 2009 Aug 8 1
46 18158874 Dynamic effects of autophagy on arsenic trioxide-induced death of human leukemia cell line HL60 cells. 2008 Jan 1
47 18566239 Arsenic trioxide decreases AKT protein in a caspase-dependent manner. 2008 Jun 1
48 18599993 [Arsenic trioxide induced apoptosis in retinoblastoma cells in vitro and its possible mechanism]. 2008 Jun 1
49 17495969 Arsenic trioxide and proteasome inhibitor bortezomib synergistically induce apoptosis in leukemic cells: the role of protein kinase Cdelta. 2007 Jul 1
50 17531122 Berbamine selectively induces apoptosis of human acute promyelocytic leukemia cells via survivin-mediated pathway. 2007 May 5 2