acetyl-aspartyl-glutamyl-valyl-aspartal

caspase 3 ; Homo sapiens







155 Article(s)
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1 30669111 OPFRs and BFRs induced A549 cell apoptosis by caspase-dependent mitochondrial pathway. 2019 Apr 1
2 30710195 Chemotherapeutic paclitaxel and cisplatin differentially induce pyroptosis in A549 lung cancer cells via caspase-3/GSDME activation. 2019 Apr 1
3 31357025 TRIM13 inhibited cell proliferation and induced cell apoptosis by regulating NF-κB pathway in non-small-cell lung carcinoma cells. 2019 Oct 5 2
4 28856634 The anti-tumor effect of pachymic acid on osteosarcoma cells by inducing PTEN and Caspase 3/7-dependent apoptosis. 2018 Jan 1
5 29223591 Mild hypothermia protects hippocampal neurons from oxygen-glucose deprivation injury through inhibiting caspase-3 activation. 2018 Feb 4
6 27888812 A polysaccharide from Lentinus edodes inhibits human colon cancer cell proliferation and suppresses tumor growth in athymic nude mice. 2017 Jan 3 1
7 26428367 Antitumor activity of ginseng sapogenins, 25-OH-PPD and 25-OCH3-PPD, on gastric cancer cells. 2016 Jan 1
8 26980707 Oridonin, a novel lysine acetyltransferases inhibitor, inhibits proliferation and induces apoptosis in gastric cancer cells through p53- and caspase-3-mediated mechanisms. 2016 Apr 19 1
9 27003995 Melittin induces human gastric cancer cell apoptosis via activation of mitochondrial pathway. 2016 Mar 21 2
10 27106530 Cucurbitacin E induces caspase-dependent apoptosis and protective autophagy mediated by ROS in lung cancer cells. 2016 Jun 25 1
11 25218199 Homogeneous detection of caspase-3 using intrinsic fluorescence resonance energy transfer (iFRET). 2015 May 15 1
12 25331424 Ac-tLeu-Asp-H is the minimal and highly effective human caspase-3 inhibitor: biological and in silico studies. 2015 Jan 1
13 25712669 Matrine suppresses proliferation and induces apoptosis in human cholangiocarcinoma cells through suppression of JAK2/STAT3 signaling. 2015 Apr 1
14 26210547 HMME combined with green light-emitting diode irradiation results in efficient apoptosis on human tongue squamous cell carcinoma. 2015 Sep 2
15 24519064 Dihydroartemisinin induces apoptosis in colorectal cancer cells through the mitochondria-dependent pathway. 2014 Jun 1
16 24607806 HOCl-modified phosphatidylcholines induce apoptosis and redox imbalance in HUVEC-ST cells. 2014 Apr 15 1
17 24842412 Arctigenin promotes apoptosis in ovarian cancer cells via the iNOS/NO/STAT3/survivin signalling. 2014 Dec 1
18 25026173 DADS suppresses human esophageal xenograft tumors through RAF/MEK/ERK and mitochondria-dependent pathways. 2014 Jul 14 1
19 25109431 Raltitrexed induces mitochondrial‑mediated apoptosis in SGC7901 human gastric cancer cells. 2014 Oct 1
20 23079083 Bortezomib/proteasome inhibitor triggers both apoptosis and autophagy-dependent pathways in melanoma cells. 2013 Jan 1
21 23442976 Caspase-3 mediated release of SAC domain containing fragment from Par-4 is necessary for the sphingosine-induced apoptosis in Jurkat cells. 2013 Feb 27 1
22 24039967 Searching in mother nature for anti-cancer activity: anti-proliferative and pro-apoptotic effect elicited by green barley on leukemia/lymphoma cells. 2013 1
23 21211949 The furano norclerodane diterpenoid disobulbin-D induces apoptosis in normal human liver L-02 cells. 2012 Sep 1
24 22948973 Induction of apoptosis by 7-piperazinethylchrysin in HCT-116 human colon cancer cells. 2012 Nov 1
25 23023390 Differential proteomic analysis of HL60 cells treated with secalonic acid F reveals caspase 3-induced cleavage of Rho GDP dissociation inhibitor 2. 2012 Dec 1
26 20981869 Caudatin-2,6-dideoxy-3-O-methy-β-D-cymaropyranoside 1 induced apoptosis through caspase 3-dependent pathway in human hepatoma cell line SMMC7721. 2011 May 2
27 22130238 Decreases in CD31 and CD47 levels on the cell surface during etoposide-induced Jurkat cell apoptosis. 2011 1
28 20427168 Inhibition of caspase-3 differentially affects vascular smooth muscle cell apoptosis in the concave versus convex aortic sites in ascending aneurysms with a bicuspid aortic valve. 2010 May 20 2
29 21229646 Endoplasmic reticulum stress associated with caspases-4 and -2 mediates korbazol-induced B-chronic lymphocytic leukemia cell apoptosis. 2010 Oct-Dec 1
30 18041091 alpha-Amino-3-hydroxy-5-methyl-4-isoxazole propionate attenuates glutamate-induced caspase-3 cleavage via regulation of glycogen synthase kinase 3beta. 2008 Apr 1
31 18494000 Emodin inhibits TNF-alpha-induced human aortic smooth-muscle cell proliferation via caspase- and mitochondrial-dependent apoptosis. 2008 Sep 1 1
32 18504415 Interaction of the HMG-CoA reductase inhibitor lovastatin and nitric oxide in cardiomyocyte cell death. 2008 1
33 19175174 [Effects of p,p'-DDE and beta-BHC on the apoptosis of Sertoli cells in vitro]. 2008 Sep 1
34 17050058 Inhibition of 12-lipoxygenase during baicalein-induced human lung nonsmall carcinoma H460 cell apoptosis. 2007 Mar 2
35 17240509 Emodin induces apoptosis through caspase 3-dependent pathway in HK-2 cells. 2007 Mar 7 1
36 17419000 Mechanism of tert-butylhydroperoxide induced cytotoxicity in U-937 macrophages by alteration of mitochondrial function and generation of ROS. 2007 Aug 2
37 17487501 Inhibition of UVA-induced apoptotic signaling pathway by polypeptide from Chlamys farreri in human HaCaT keratinocytes. 2007 Aug 2
38 17498978 Analysis of aclarubicin-induced cell death in human fibroblasts. 2007 Sep 1
39 17594508 Structural and functional definition of the specificity of a novel caspase-3 inhibitor, Ac-DNLD-CHO. 2007 Jun 27 1
40 17643408 Inhibition of angiogenic tubule formation and induction of apoptosis in human endothelial cells by the selective cyclooxygenase-2 inhibitor 5-bromo-2-(4-fluorophenyl)-3-(methylsulfonyl) thiophene (DuP-697). 2007 Nov 14 1
41 16267630 R(+)-methanandamide elicits a cyclooxygenase-2-dependent mitochondrial apoptosis signaling pathway in human neuroglioma cells. 2006 Jan 2
42 16458118 Petrotetrayndiol A induces cell cycle arrest and apoptosis in SK-MEL-2 human melanoma cells through cytochrome c-mediated activation of caspases. 2006 Feb 8 1
43 16781734 Structural and kinetic analysis of caspase-3 reveals role for s5 binding site in substrate recognition. 2006 Jul 14 1
44 16879316 Melatonin protects against hydrogen peroxide-induced cell death signaling in SH-SY5Y cultured cells: involvement of nuclear factor kappa B, Bax and Bcl-2. 2006 Sep 1
45 17016583 Characterization of mitochondria in cisplatin-resistant human ovarian carcinoma cells. 2006 Nov 1
46 15639343 Asiatic acid induces apoptosis in SK-MEL-2 human melanoma cells. 2005 Jan 31 1
47 15710362 Mechanism of ricin-induced apoptosis in human cervical cancer cells. 2005 Mar 1 2
48 15720039 A convenient fluorometric method to study sulfur mustard-induced apoptosis in human epidermal keratinocytes monolayer microplate culture. 2005 4
49 15936354 Scopoletin induces apoptosis in human promyeloleukemic cells, accompanied by activations of nuclear factor kappaB and caspase-3. 2005 Jul 1 2
50 15960610 Regulation of cell survival by lipid phosphate phosphatases involves the modulation of intracellular phosphatidic acid and sphingosine 1-phosphate pools. 2005 Oct 1 1