Docetaxel

caspase 3 ; Homo sapiens







53 Article(s)
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1 32578137 Melatonin and Selenium Suppress Docetaxel-Induced TRPV1 Activation, Neuropathic Pain and Oxidative Neurotoxicity in Mice. 2021 Apr 1
2 33775687 Roles of CYP3A4, CYP3A5 and CYP2C8 drug-metabolizing enzymes in cellular cytostatic resistance. 2021 May 1 1
3 34787067 Zafirlukast ameliorates Docetaxel-induced activation of NOD-like receptor protein 3 (NLRP3) inflammasome, mediated by sirtuin1 (SIRT1) in hepatocytes. 2021 Dec 1
4 32371266 Synthesis of micellar-like terpolymer nanoparticles with reductively-cleavable cross-links and evaluation of efficacy in 2D and 3D models of triple negative breast cancer. 2020 Jul 10 1
5 32994029 LHRH-conjugated, PEGylated, poly-lactide-co-glycolide nanocapsules for targeted delivery of combinational chemotherapeutic drugs Docetaxel and Quercetin for prostate cancer. 2020 Sep 1
6 33408886 Tryptophanyl-tRNA Synthetase Sensitizes Hormone Receptor-Positive Breast Cancer to Docetaxel-Based Chemotherapy. 2020 Dec 1
7 30880686 The transcription factor ZEB1 promotes chemoresistance in prostate cancer cell lines. 2019 Sep-Oct 1
8 31470686 Molecular Mechanisms of Antitumor Activity of PAMAM Dendrimer Conjugates with Anticancer Drugs and a Monoclonal Antibody. 2019 Aug 29 1
9 31540423 Docetaxel Combined with Thymoquinone Induces Apoptosis in Prostate Cancer Cells via Inhibition of the PI3K/AKT Signaling Pathway. 2019 Sep 18 1
10 29301832 Pharmacological Inhibition of NOS Activates ASK1/JNK Pathway Augmenting Docetaxel-Mediated Apoptosis in Triple-Negative Breast Cancer. 2018 Mar 1 1
11 30061946 CCL2 influences the sensitivity of lung cancer A549 cells to docetaxel. 2018 Jul 1
12 30519344 Oncolytic Adenovirus Harboring Interleukin-24 Improves Chemotherapy for Advanced Prostate Cancer. 2018 1
13 30555232 Activation of polymeric nanoparticle intracellular targeting overcomes chemodrug resistance in human primary patient breast cancer cells. 2018 1
14 27840955 miR-141 regulation of EIF4E expression affects docetaxel chemoresistance of non-small cell lung cancer. 2017 Jan 2
15 28440463 Livin enhances chemoresistance in head and neck squamous cell carcinoma. 2017 Jun 1
16 28799743 Reducing Interstitial Fluid Pressure and Inhibiting Pulmonary Metastasis of Breast Cancer by Gelatin Modified Cationic Lipid Nanoparticles. 2017 Sep 6 1
17 28981599 DKK4-knockdown enhances chemosensitivity of A549/DTX cells to docetaxel. 2017 Oct 1 1
18 27035282 Anticancer effect of docetaxel induces apoptosis of prostate cancer via the cofilin-1 and paxillin signaling pathway. 2016 May 2
19 27082738 Docetaxel induces Bcl-2- and pro-apoptotic caspase-independent death of human prostate cancer DU145 cells. 2016 Jun 1
20 27153245 Growth Arrest-Specific 6 (GAS6) Promotes Prostate Cancer Survival by G1 Arrest/S Phase Delay and Inhibition of Apoptosis During Chemotherapy in Bone Marrow. 2016 Dec 1
21 27340870 ST6Gal-I modulates docetaxel sensitivity in human hepatocarcinoma cells via the p38 MAPK/caspase pathway. 2016 Aug 9 1
22 27686228 The UCA1/miR-204/Sirt1 axis modulates docetaxel sensitivity of prostate cancer cells. 2016 Nov 1
23 25634538 Docetaxel Facilitates Endothelial Dysfunction through Oxidative Stress via Modulation of Protein Kinase C Beta: The Protective Effects of Sotrastaurin. 2015 May 1
24 25708950 Paradoxical effects of the autophagy inhibitor 3-methyladenine on docetaxel-induced toxicity in PC-3 and LNCaP prostate cancer cells. 2015 Jul 1
25 24839986 Restoration of fibroblast growth factor receptor 2IIIb enhances the chemosensitivity of human prostate cancer cells. 2014 Jul 2
26 25138252 Liposome-based co-delivery of siRNA and docetaxel for the synergistic treatment of lung cancer. 2014 Oct 20 1
27 23138939 γ-tocotrienol enhances the chemosensitivity of human oral cancer cells to docetaxel through the downregulation of the expression of NF-κB-regulated anti-apoptotic gene products. 2013 Jan 1
28 24155950 Combination of bortezomib and mitotic inhibitors down-modulate Bcr-Abl and efficiently eliminates tyrosine-kinase inhibitor sensitive and resistant Bcr-Abl-positive leukemic cells. 2013 1
29 24432379 Synergistic antitumor activities of sepantronium bromide (YM155), a survivin suppressant, in combination with microtubule-targeting agents in triple-negative breast cancer cells. 2013 1
30 22490358 [The effect of cell killing by ABT-737 synergized with docetaxel in human prostate cancer PC-3 cells]. 2012 Feb 1 1
31 22858003 Enhanced docetaxel-mediated cytotoxicity in human prostate cancer cells through knockdown of cofilin-1 by carbon nanohorn delivered siRNA. 2012 Nov 1
32 22994780 Histone deacetylase inhibitor trichostatin A enhances anti-tumor effects of docetaxel or erlotinib in A549 cell line. 2012 1
33 21273177 Randomized phase II trial of concurrent versus sequential bortezomib plus docetaxel in advanced non-small-cell lung cancer: a California cancer consortium trial. 2011 Jan 1
34 20057500 Noninvasive molecular imaging of apoptosis in vivo using a modified firefly luciferase substrate, Z-DEVD-aminoluciferin. 2010 Jun 1
35 20878124 Replication-dependent γ-H2AX formation is involved in docetaxel-induced apoptosis in NSCLC A549 cells. 2010 Nov 1
36 19147759 Enhancement of docetaxel anticancer activity by a novel diindolylmethane compound in human non-small cell lung cancer. 2009 Jan 15 1
37 19369859 Inhibition of functional HER family members increases the sensitivity to docetaxel in human ovarian cancer cell lines. 2009 Jul 1
38 19490758 Docetaxel enhances the cytotoxic effects of imatinib on Philadelphia positive human chronic myeloid leukemia cells. 2009 Jun 1
39 20044612 Tumor-specific cytotoxicity and type of cell death induced by gefitinib in oral squamous cell carcinoma cell lines. 2009 Dec 1
40 18190795 Overexpression of phospholipase D suppresses taxotere-induced cell death in stomach cancer cells. 2008 May 1
41 18957056 Synergistic interaction between trifluorothymidine and docetaxel is sequence dependent. 2008 Nov 1
42 18006775 AMG 102, a fully human anti-hepatocyte growth factor/scatter factor neutralizing antibody, enhances the efficacy of temozolomide or docetaxel in U-87 MG cells and xenografts. 2007 Nov 15 1
43 18186959 Schedule-dependent apoptosis in K-ras mutant non-small-cell lung cancer cell lines treated with docetaxel and erlotinib: rationale for pharmacodynamic separation. 2007 Nov 1
44 16536899 Anti-cancer effect of celecoxib and aerosolized docetaxel against human non-small cell lung cancer cell line, A549. 2006 Mar 2
45 16149076 Amplification loop cascade for increasing caspase activity induced by docetaxel. 2005 Nov 1 1
46 16361572 Focal adhesion kinase silencing augments docetaxel-mediated apoptosis in ovarian cancer cells. 2005 Dec 15 3
47 15282376 Genome-wide discovery of loci influencing chemotherapy cytotoxicity. 2004 Aug 10 1
48 15331178 Comparison of burst of reactive oxygen species and activation of caspase-3 in apoptosis of K562 and HL-60 cells induced by docetaxel. 2004 Oct 8 2
49 15492266 HIV-1 protease inhibitor, ritonavir: a potent inhibitor of CYP3A4, enhanced the anticancer effects of docetaxel in androgen-independent prostate cancer cells in vitro and in vivo. 2004 Oct 15 1
50 15566641 [Enhancement of FG020326 on sensitivity of MCF-7/ADR cells to taxotere via enhancing activation of caspase-8 and caspase-3]. 2004 Nov 4