Imatinib Mesylate

caspase 3 ; Homo sapiens







37 Article(s)
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1 33607534 Assessment of azithromycin as an anticancer agent for treatment of imatinib sensitive and resistant CML cells. 2021 Mar 1
2 34031270 Platelet-Derived Growth Factor Receptor-α Subunit Targeting Suppresses Metastasis in Advanced Thyroid Cancer In Vitro and In Vivo. 2021 Sep 1 1
3 34781823 Protein disulfide isomerase family 6 promotes the imatinib-resistance of renal cell carcinoma by regulation of Wnt3a-Frizzled1 axis. 2021 Dec 1
4 33022360 Imatinib exhibit synergistic pleiotropy in the prevention of colorectal cancer by suppressing proinflammatory, cell survival and angiogenic signaling. 2020 Dec 1
5 29298654 Determination of the Apoptotic Effect and Molecular Docking of Benzamide Derivative XT5 in K562 Cells. 2018 1
6 28255316 Imatinib and its combination with 2,5-dimethyl-celecoxibinduces apoptosis of human HT-29 colorectal cancer cells. 2017 Feb 2
7 28612529 [The Mechanism of Combination using mTORC1/2 Inhibitor and Imatinib to Suppress Cell Proliferation of Ph +ALL Cell Line]. 2017 Mar 1
8 26708080 Imatinib promotes apoptosis of giant cell tumor cells by targeting microRNA-30a-mediated runt-related transcription factor 2. 2016 Feb 1
9 24930392 Modulation of imatinib cytotoxicity by selenite in HCT116 colorectal cancer cells. 2015 Jan 1
10 25786656 Paradoxical and contradictory effects of imatinib in two cell line models of hormone-refractory prostate cancer. 2015 Jun 15 1
11 24088895 Activin A induction of erythroid differentiation sensitizes K562 chronic myeloid leukemia cells to a subtoxic concentration of imatinib. 2014 Jan 1 2
12 24527087 In vitro effects of imatinib on CD34+ cells of patients with chronic myeloid leukemia in the megakaryocytic crisis phase. 2014 Mar 1
13 25322553 [Gleevec induces apoptosis in K562 cells through activating caspase-3]. 2014 Aug 2
14 23434731 Cleavage of BCR-ABL transcripts at the T315I point mutation by DNAzyme promotes apoptotic cell death in imatinib-resistant BCR-ABL leukemic cells. 2013 Aug 1
15 23613979 Aclacinomycin A sensitizes K562 chronic myeloid leukemia cells to imatinib through p38MAPK-mediated erythroid differentiation. 2013 2
16 22388075 Imatinib induces H2AX phosphorylation and apoptosis in chronic myelogenous leukemia cells in vitro via caspase-3/Mst1 pathway. 2012 Apr 5
17 21658383 Apoptotic effect of imatinib on human colon adenocarcinoma cells: influence on actin cytoskeleton organization and cell migration. 2011 Sep 30 1
18 20031210 Molecular characterization and prognostic significance of FLT3 in CML progression. 2010 Aug 1
19 20094798 Enhancement of imatinib-induced apoptosis of BCR/ABL-expressing cells by nutlin-3 through synergistic activation of the mitochondrial apoptotic pathway. 2010 May 2
20 20132660 Nilotinib significantly induces apoptosis in imatinib-resistant K562 cells with wild-type BCR-ABL, as effectively as in parental sensitive counterparts. 2010 Feb 1
21 20307198 Combination of fludarabine and imatinib induces apoptosis synergistically through loss of mitochondrial membrane potential and increases in caspase-3 enzyme activity in human K562 chronic myleloid leukemia cells. 2010 Jul 1
22 20723293 [Effects of STI571 combined with As₂O₃ on proliferation, apoptosis and caspase 3, Bcl-xL expression of K562 cells]. 2010 Aug 4
23 19058199 Metronomic scheduling of imatinib abrogates clonogenicity of neuroblastoma cells and enhances their susceptibility to selected chemotherapeutic drugs in vitro and in vivo. 2009 Mar 1 1
24 19340007 Inhibition of imatinib-mediated apoptosis by the caspase-cleaved form of the tyrosine kinase Lyn in chronic myelogenous leukemia cells. 2009 Aug 1
25 19490758 Docetaxel enhances the cytotoxic effects of imatinib on Philadelphia positive human chronic myeloid leukemia cells. 2009 Jun 1
26 18401414 Sphingosine kinase-1 is a downstream regulator of imatinib-induced apoptosis in chronic myeloid leukemia cells. 2008 May 1
27 18843975 [Imatinib induces c-kit positive myeloma cells apoptosis]. 2008 Apr 1
28 17926190 (-)Gossypol and its combination with imatinib induce apoptosis in human chronic myeloid leukemic cells. 2007 Nov 1
29 16596277 STI571 (Glivec) induces cell death in the gastrointestinal stromal tumor cell line, GIST-T1, via endoplasmic reticulum stress response. 2006 May 1
30 15657060 c-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damage. 2005 Mar 25 1
31 15770664 Fast apoptosis and erythroid differentiation induced by imatinib mesylate in JURL-MK1 cells. 2005 May 15 1
32 12850478 Involvement of Akt kinase in the action of STI571 on chronic myelogenous leukemia cells. 2003 Jul-Aug 2
33 11782377 Pharmacologic mitogen-activated protein/extracellular signal-regulated kinase kinase/mitogen-activated protein kinase inhibitors interact synergistically with STI571 to induce apoptosis in Bcr/Abl-expressing human leukemia cells. 2002 Jan 1 1
34 12021410 Inhibition of c-Abl with STI571 attenuates stress-activated protein kinase activation and apoptosis in the cellular response to 1-beta-D-arabinofuranosylcytosine. 2002 Jun 1
35 12231544 Flavopiridol potentiates STI571-induced mitochondrial damage and apoptosis in BCR-ABL-positive human leukemia cells. 2002 Sep 1
36 12411057 The mechanism of STI571 inducing apoptosis of K562 cells. 2002 Jun 1
37 11179439 The catalytic DNA topoisomerase II inhibitor dexrazoxane (ICRF-187) induces differentiation and apoptosis in human leukemia K562 cells. 2001 Mar 1