Staurosporine

caspase 3 ; Homo sapiens







158 Article(s)
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101 12565805 Decreased caspase-3 activity in human lens epithelium from posterior subcapsular cataracts. 2003 Feb 1
102 12581734 Staurosporine-induced death of MCF-7 human breast cancer cells: a distinction between caspase-3-dependent steps of apoptosis and the critical lethal lesions. 2003 Feb 15 4
103 12598452 Mechanisms of staurosporine induced apoptosis in a human corneal endothelial cell line. 2003 Mar 2
104 12721754 Staurosporine-induced apoptosis is independent of p16 and p21 and achieved via arrest at G2/M and at G1 in U251MG human glioma cell line. 2003 Apr 1
105 14570914 Caspase 3-mediated proteolysis of the N-terminal cytoplasmic domain of the human erythroid anion exchanger 1 (band 3). 2003 Dec 26 2
106 15033698 G-CSF modulates LPS-induced apoptosis and IL-8 in human microvascular endothelial cells: involvement of calcium signaling. 2003 Dec 1
107 11943195 Mutant huntingtin aggregates do not sensitize cells to apoptotic stressors. 2002 Mar 27 1
108 12032672 Taxol-induced apoptosis in human SKOV3 ovarian and MCF7 breast carcinoma cells is caspase-3 and caspase-9 independent. 2002 Jun 2
109 12051665 7-Ketocholesterol and staurosporine induce opposite changes in intracellular pH, associated with distinct types of cell death in ECV304 cells. 2002 Jun 15 1
110 12065637 Tissue transglutaminase differentially modulates apoptosis in a stimuli-dependent manner. 2002 May 1
111 12154052 The Poly(ADP-ribose) polymerase-1-regulated endonuclease DNAS1L3 is required for etoposide-induced internucleosomal DNA fragmentation and increases etoposide cytotoxicity in transfected osteosarcoma cells. 2002 Aug 1 1
112 12234376 BRCA1 Zinc RING Finger Domain Disruption Alters Caspase Response in Ovarian Surface Epithelial Cells. 2002 Jul 5 1
113 12373608 Apoptotic mechanisms in T47D and MCF-7 human breast cancer cells. 2002 Oct 7 1
114 12443983 Citicoline increases glutathione redox ratio and reduces caspase-3 activation and cell death in staurosporine-treated SH-SY5Y human neuroblastoma cells. 2002 Dec 6 2
115 11154867 DNA-dependent protein kinase catalytic subunit is cleaved during UV-induced apoptosis. 2001 Jan 1
116 11162250 Proapoptotic effects of tau cleavage product generated by caspase-3. 2001 Feb 2
117 11296547 Non-steroidal anti-inflammatory drugs protect against chondrocyte apoptotic death. 2001 2
118 11426445 Dissipation of potassium and proton gradients inhibits mitochondrial hyperpolarization and cytochrome c release during neural apoptosis. 2001 Jul 1 1
119 11463339 Measurement of proteases using chemiluminescence-resonance-energy-transfer chimaeras between green fluorescent protein and aequorin. 2001 Aug 1 1
120 11479289 Caspase-mediated cleavage of the Ca2+/calmodulin-dependent protein kinase-like kinase facilitates neuronal apoptosis. 2001 Oct 19 1
121 11495916 Proapoptotic stimuli induce nuclear accumulation of glycogen synthase kinase-3 beta. 2001 Oct 5 1
122 11570504 Detection of caspase activation in situ by fluorochrome-labeled caspase inhibitors. 2001 Sep 1
123 10663630 Actinomycin D and staurosporine, potent apoptosis inducers in vitro, are potentially effective chemotherapeutic agents against glioblastoma multiforme. 2000 1
124 10679755 Heterogeneous apoptotic responses of prostate cancer cell lines identify an association between sensitivity to staurosporine-induced apoptosis, expression of Bcl-2 family members, and caspase activation. 2000 Mar 1 1
125 10708590 Mitochondria and caspases in induced apoptosis in human luteinized granulosa cells. 2000 Mar 16 1
126 10713065 Glycogen synthase kinase-3beta facilitates staurosporine- and heat shock-induced apoptosis. Protection by lithium. 2000 Mar 17 3
127 10734071 Caspase-8 activation and bid cleavage contribute to MCF7 cellular execution in a caspase-3-dependent manner during staurosporine-mediated apoptosis. 2000 Mar 31 1
128 10762713 Poly (ADP-ribose) polymerase induction is an early signal of apoptosis in human neuroblastoma. 2000 Mar 29 1
129 10933864 Quantification of active caspase 3 in apoptotic cells. 2000 Aug 15 1
130 10934034 Effector caspases are dispensable for the early nuclear morphological changes during chemical-induced apoptosis. 2000 Sep 2
131 10955723 Different sublines of Jurkat cells respond with varying susceptibility of internucleosomal DNA degradation to different mediators of apoptosis. 2000 Aug 1
132 10998058 Caspase-3 mediated cleavage of HsRad51 at an unconventional site. 2000 Oct 2
133 11058115 Proteolysis of the human DNA polymerase epsilon catalytic subunit by caspase-3 and calpain specifically during apoptosis. 2000 Nov 1 1
134 11146107 Staurosporine- and H-7-induced cell death in SH-SY5Y neuroblastoma cells is associated with caspase-2 and caspase-3 activation, but not with activation of the FAS/FAS-L-caspase-8 signaling pathway. 2000 Dec 28 2
135 11187905 Resistance to CD95-mediated apoptosis through constitutive c-FLIP expression in a non-Hodgkin's lymphoma B cell line. 2000 Dec 1
136 9927051 Signaling pathway activated during apoptosis of the prostate cancer cell line LNCaP: overexpression of caspase-7 as a new gene therapy strategy for prostate cancer. 1999 Jan 15 1
137 9949201 The Friedreich's ataxia mutation confers cellular sensitivity to oxidant stress which is rescued by chelators of iron and calcium and inhibitors of apoptosis. 1999 Mar 2
138 10037154 Phosphatidylinositol 3-kinase and protein kinase C are required for the inhibition of caspase activity by epidermal growth factor. 1999 Feb 5 1
139 10205158 Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of jurkat cells. 1999 Apr 15 1
140 10375546 Novel mutant green fluorescent protein protease substrates reveal the activation of specific caspases during apoptosis. 1999 Jun 1
141 10409669 Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c. 1999 Jul 23 1
142 10438458 Role of poly(ADP-ribose) polymerase (PARP) cleavage in apoptosis. Caspase 3-resistant PARP mutant increases rates of apoptosis in transfected cells. 1999 Aug 13 1
143 10477698 Modulation of caspase-8 and FLICE-inhibitory protein expression as a potential mechanism of Epstein-Barr virus tumorigenesis in Burkitt's lymphoma. 1999 Sep 1 1
144 10486259 Procaspase-3 and poly(ADP)ribose polymerase (PARP) are calpain substrates. 1999 Sep 16 1
145 10497198 Cleavage of automodified poly(ADP-ribose) polymerase during apoptosis. Evidence for involvement of caspase-7. 1999 Oct 1 1
146 10514472 Cytochrome c-mediated apoptosis in cells lacking mitochondrial DNA. Signaling pathway involving release and caspase 3 activation is conserved. 1999 Oct 15 1
147 10567423 Inositol 1,4,5-trisphosphate receptor type 1 is a substrate for caspase-3 and is cleaved during apoptosis in a caspase-3-dependent manner. 1999 Nov 26 1
148 10582585 Staurosporine-induced activation of caspase-3 is potentiated by presenilin 1 familial Alzheimer's disease mutations in human neuroglioma cells. 1999 Dec 2
149 10728572 Apoptosis induced by gamma irradiation in peripheral blood mononuclear cells is not mediated by cytochrome-c release and only partially involves caspase-3-like proteases. 1999 1
150 9515027 Staurosporine-induced apoptosis in cardiomyocytes: A potential role of caspase-3. 1998 Mar 3