Hydrogen Peroxide

nuclear factor, erythroid derived 2, like 2 ; Mus musculus







82 Article(s)
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51 26830132 The cytoprotective effect of isorhamnetin against oxidative stress is mediated by the upregulation of the Nrf2-dependent HO-1 expression in C2C12 myoblasts through scavenging reactive oxygen species and ERK inactivation. 2016 Apr 2
52 26936880 Myeloid-Derived Suppressor Cell Survival and Function Are Regulated by the Transcription Factor Nrf2. 2016 Apr 15 1
53 27082826 The herbal extract KCHO-1 exerts a neuroprotective effect by ameliorating oxidative stress via heme oxygenase-1 upregulation. 2016 Jun 1
54 27300700 MicroRNA-93 Downregulation Ameliorates Cerebral Ischemic Injury Through the Nrf2/HO-1 Defense Pathway. 2016 Oct 1
55 27412767 Role of CREB on heme oxygenase-1 induction in adrenal cells: involvement of the PI3K pathway. 2016 Aug 1
56 27427974 Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes. 2016 Oct 2 1
57 27515402 Methylene blue improves sensorimotor phenotype and decreases anxiety in parallel with activating brain mitochondria biogenesis in mid-age mice. 2016 Dec 1
58 27535021 Berberine Hydrochloride Protects C2C12 Myoblast Cells Against Oxidative Stress-Induced Damage via Induction of Nrf-2-Mediated HO-1 Expression. 2016 Sep 1
59 27669641 Downregulation of Nrf2 promotes autophagy-dependent osteoblastic differentiation of adipose-derived mesenchymal stem cells. 2016 Dec 10 1
60 25557231 Baicalein Decreases Hydrogen Peroxide-Induced Damage to NG108-15 Cells via Upregulation of Nrf2. 2015 Aug 8
61 26303969 N-acetyl cysteine inhibits H2O2-mediated reduction in the mineralization of MC3T3-E1 cells by down-regulating Nrf2/HO-1 pathway. 2015 Nov 5
62 24812425 Catalase overexpression prevents nuclear factor erythroid 2-related factor 2 stimulation of renal angiotensinogen gene expression, hypertension, and kidney injury in diabetic mice. 2014 Oct 2
63 24835026 Protective effect of coconut water concentrate and its active component shikimic acid against hydroperoxide mediated oxidative stress through suppression of NF-κB and activation of Nrf2 pathway. 2014 Aug 8 1
64 25200066 Activation of the Nrf2-ARE pathway attenuates hyperglycemia-mediated injuries in mouse podocytes. 2014 1
65 25493944 Nrf2-mediated HO-1 induction contributes to antioxidant capacity of a Schisandrae Fructus ethanol extract in C2C12 myoblasts. 2014 Dec 1
66 23597505 The transcription factor Nrf2 promotes survival by enhancing the expression of uncoupling protein 3 under conditions of oxidative stress. 2013 Aug 3
67 23867319 KEAP1-NRF2 complex in ischemia-induced hepatocellular damage of mouse liver transplants. 2013 Dec 1
68 24216104 Carvedilol, a third-generation β-blocker prevents oxidative stress-induced neuronal death and activates Nrf2/ARE pathway in HT22 cells. 2013 Nov 29 1
69 22469516 Berberine activates Nrf2 nuclear translocation and protects against oxidative damage via a phosphatidylinositol 3-kinase/Akt-dependent mechanism in NSC34 motor neuron-like cells. 2012 Aug 15 1
70 20978266 Nrf2 and selenoproteins are essential for maintaining oxidative homeostasis in erythrocytes and protecting against hemolytic anemia. 2011 Jan 20 1
71 21159318 γ-Glutamylcysteine ameliorates oxidative injury in neurons and astrocytes in vitro and increases brain glutathione in vivo. 2011 Oct 2
72 21211512 Transcription factor Nrf2 maintains the basal expression of Mdm2: An implication of the regulation of p53 signaling by Nrf2. 2011 Mar 15 1
73 21270272 Diabetic downregulation of Nrf2 activity via ERK contributes to oxidative stress-induced insulin resistance in cardiac cells in vitro and in vivo. 2011 Feb 1
74 19933842 Nrf2 signaling, a mechanism for cellular stress resistance in long-lived mice. 2010 Feb 1
75 20600948 Expression, purification, and refolding of active Nrf2 transcription factor fused to protein transduction TAT tag. 2010 Dec 1
76 18814142 Functional expression of beta2 adrenergic receptors responsible for protection against oxidative stress through promotion of glutathione synthesis after Nrf2 upregulation in undifferentiated mesenchymal C3H10T1/2 stem cells. 2009 Feb 1
77 19303893 Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents. 2009 Jun 15 1
78 19351736 Nrf2-dependent upregulation of antioxidative enzymes: a novel pathway for proteasome inhibitor-mediated cardioprotection. 2009 Jul 15 4
79 18463988 Nuclear factor E2-related factor 2-dependent myocardiac cytoprotection against oxidative and electrophilic stress. 2008 Summer 1
80 17394461 Dopamine activates Nrf2-regulated neuroprotective pathways in astrocytes and meningeal cells. 2007 Apr 1
81 16863997 ATM controls c-Myc and DNA synthesis during postnatal thymocyte development through regulation of redox state. 2006 Aug 15 1
82 15210949 Targeted disruption of Nrf2 causes regenerative immune-mediated hemolytic anemia. 2004 Jun 29 1