vandetanib

kinase insert domain receptor ; Homo sapiens







115 Article(s)
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101 16791411 A phase II study of ZD6474 (Zactima, a selective inhibitor of VEGFR and EGFR tyrosine kinase in patients with relapsed multiple myeloma--NCIC CTG IND.145. 2006 Nov 2
102 16843002 New antiangiogenetic agents and non-small cell lung cancer. 2006 Oct 1
103 16891475 Sequence-dependent inhibition of human colon cancer cell growth and of prosurvival pathways by oxaliplatin in combination with ZD6474 (Zactima), an inhibitor of VEGFR and EGFR tyrosine kinases. 2006 Jul 3
104 17136225 Vandetanib, a novel multitargeted kinase inhibitor, in cancer therapy. 2006 Oct 2
105 17145834 Synergistic antitumor activity of ZD6474, an inhibitor of vascular endothelial growth factor receptor and epidermal growth factor receptor signaling, with gemcitabine and ionizing radiation against pancreatic cancer. 2006 Dec 1 1
106 15867237 A multicenter phase II trial of ZD6474, a vascular endothelial growth factor receptor-2 and epidermal growth factor receptor tyrosine kinase inhibitor, in patients with previously treated metastatic breast cancer. 2005 May 1 3
107 15928657 ZD6474--a novel inhibitor of VEGFR and EGFR tyrosine kinase activity. 2005 Jun 1
108 16061883 Cooperative antitumor effect of multitargeted kinase inhibitor ZD6474 and ionizing radiation in glioblastoma. 2005 Aug 1 1
109 16361567 Antitumor vascular strategy for controlling experimental metastatic spread of human small-cell lung cancer cells with ZD6474 in natural killer cell-depleted severe combined immunodeficient mice. 2005 Dec 15 4
110 15367698 ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor with additional activity against epidermal growth factor receptor tyrosine kinase, inhibits orthotopic growth and angiogenesis of gastric cancer. 2004 Sep 2
111 15596048 Anticancer effects of ZD6474, a VEGF receptor tyrosine kinase inhibitor, in gefitinib ("Iressa")-sensitive and resistant xenograft models. 2004 Dec 2
112 15604279 Small in-frame deletion in the epidermal growth factor receptor as a target for ZD6474. 2004 Dec 15 3
113 15623642 ZD6474, a potent inhibitor of vascular endothelial growth factor signaling, combined with radiotherapy: schedule-dependent enhancement of antitumor activity. 2004 Dec 15 2
114 12684431 Antitumor effects of ZD6474, a small molecule vascular endothelial growth factor receptor tyrosine kinase inhibitor, with additional activity against epidermal growth factor receptor tyrosine kinase. 2003 Apr 1
115 14612898 Use of dynamic contrast-enhanced MRI to evaluate acute treatment with ZD6474, a VEGF signalling inhibitor, in PC-3 prostate tumours. 2003 Nov 17 1