Sunitinib

kinase insert domain receptor ; Homo sapiens







166 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
101 22444679 Radioiodinated sunitinib as a potential radiotracer for imaging angiogenesis-radiosynthesis and first radiopharmacological evaluation of 5-[125I]Iodo-sunitinib. 2012 Apr 15 4
102 22572725 Antiangiogenic approaches for the treatment of advanced synovial sarcomas. 2012 Jul 2
103 22592949 Relevance of angiogenesis in neuroendocrine tumors. 2012 Jun 1
104 22607009 Sunitinib malate for the treatment of renal cell carcinoma. 2012 Jun 2
105 22819259 Blockade of NFκB activity by Sunitinib increases cell death in Bortezomib-treated endometrial carcinoma cells. 2012 Oct 1
106 22904678 The effect of bevacizumab on human malignant melanoma cells with functional VEGF/VEGFR2 autocrine and intracrine signaling loops. 2012 Jul 1
107 22967802 Preclinical evaluation of sunitinib, a multi-tyrosine kinase inhibitor, as a radiosensitizer for human prostate cancer. 2012 Sep 11 2
108 23102636 Strategic combination therapy overcomes tyrosine kinase coactivation in adrenocortical carcinoma. 2012 Dec 1
109 24451769 Systemic therapeutic approaches to advanced thyroid cancers. 2012 2
110 25806151 Angiogenesis in cancer: Anti-VEGF escape mechanisms. 2012 Mar 1
111 20872043 Phase II study of sunitinib malate in patients with recurrent high-grade glioma. 2011 Jul 1
112 21242589 Sunitinib in advanced alveolar soft part sarcoma: evidence of a direct antitumor effect. 2011 Jul 1
113 21325074 Identification of soluble candidate biomarkers of therapeutic response to sunitinib in medullary thyroid carcinoma in preclinical models. 2011 Apr 1 1
114 21447721 Two drug interaction studies of sirolimus in combination with sorafenib or sunitinib in patients with advanced malignancies. 2011 Apr 1 2
115 21463120 Sunitinib in relapsed or refractory diffuse large B-cell lymphoma: a clinical and pharmacodynamic phase II multicenter study of the NCIC Clinical Trials Group. 2011 May 2
116 21693010 Sunitinib inhibits lymphatic endothelial cell functions and lymph node metastasis in a breast cancer model through inhibition of vascular endothelial growth factor receptor 3. 2011 Jun 21 4
117 21744079 Phase I study of sunitinib and irinotecan for patients with recurrent malignant glioma. 2011 Dec 2
118 21980525 VEGFR2 translocates to the nucleus to regulate its own transcription. 2011 2
119 22038997 Pharmacodynamic study using FLT PET/CT in patients with renal cell cancer and other solid malignancies treated with sunitinib malate. 2011 Dec 15 2
120 22130231 Vascular endothelial growth factor (VEGF), VEGF receptors and their inhibitors for antiangiogenic tumor therapy. 2011 2
121 19444655 Olecranon bursitis in patients treated with sunitinib for renal cell carcinoma. 2010 Jun 2
122 19649772 Phase II study of sunitinib malate in head and neck squamous cell carcinoma. 2010 Oct 1
123 20039326 Analysis of anti-proliferative and chemosensitizing effects of sunitinib on human esophagogastric cancer cells: Synergistic interaction with vandetanib via inhibition of multi-receptor tyrosine kinase pathways. 2010 Sep 1 1
124 20072832 Sunitinib. 2010 2
125 20103629 Sunitinib acts primarily on tumor endothelium rather than tumor cells to inhibit the growth of renal cell carcinoma. 2010 Feb 1 3
126 20103668 Targeting vascular endothelial growth factor receptor in thyroid cancer: the intracellular and extracellular implications. 2010 Feb 1 1
127 20204363 Spontaneous bilateral pneumothorax in metastatic renal cell carcinoma on sunitinib therapy. 2010 Jul 1
128 20215359 Everolimus (RAD001) in the treatment of advanced renal cell carcinoma: a review. 2010 3
129 20351323 Risk of arterial thromboembolic events with sunitinib and sorafenib: a systematic review and meta-analysis of clinical trials. 2010 May 1 3
130 20599738 Sunitinib deregulates tumor adaptation to hypoxia by inhibiting HIF-1alpha synthesis in HT-29 colon cancer cells. 2010 Jul 23 1
131 20686367 SU11248, a selective tyrosine kinases inhibitor suppresses breast tumor angiogenesis and growth via targeting both tumor vasculature and breast cancer cells. 2010 Oct 1 1
132 20686603 The 4q12 amplicon in malignant peripheral nerve sheath tumors: consequences on gene expression and implications for sunitinib treatment. 2010 Jul 29 1
133 20721275 Bevacizumab demonstrates prolonged disease stabilization in patients with heavily pretreated metastatic renal cell carcinoma: a case series and review of the literature. 2010 2
134 21187479 The effects of anti-VEGFR and anti-EGFR agents on glioma cell migration through implication of growth factors with integrins. 2010 Dec 3
135 19284623 Sunitinib treatment for patients with clear-cell metastatic renal cell carcinoma: clinical outcomes and plasma angiogenesis markers. 2009 Mar 12 1
136 19318229 Growth inhibition by tyrosine kinase inhibitors in mesothelioma cell lines. 2009 Jun 2
137 19453268 Sunitinib in solid tumors. 2009 Jun 1
138 19689244 Tyrosine kinase inhibitors - a review on pharmacology, metabolism and side effects. 2009 Jun 1
139 19726307 [Establishment of homogeneous time-resolved fluorescence immunoassay for high throughput screening of protein tyrosine kinase inhibitors]. 2009 Aug 3
140 19754358 Sunitinib (SUTENT, SU11248) suppresses tumor growth and induces apoptosis in xenograft models of human hepatocellular carcinoma. 2009 Sep 3
141 19767240 Risk of bleeding with vascular endothelial growth factor receptor tyrosine-kinase inhibitors sunitinib and sorafenib: a systematic review and meta-analysis of clinical trials. 2009 Oct 4
142 19811659 Chromophobe renal cell cancer--review of the literature and potential methods of treating metastatic disease. 2009 Oct 7 1
143 19844230 Myelosuppression and kinase selectivity of multikinase angiogenesis inhibitors. 2009 Nov 17 1
144 19911111 Sunitinib paves the way for targeted therapies in neuroendocrine tumors. 2009 Dec 1
145 20877672 Significance of Tyrosine Kinase Inhibitors in the Treatment of Metastatic Breast Cancer. 2009 2
146 17505827 A phase I and pharmacokinetic study of sunitinib administered daily for 2 weeks, followed by a 1-week off period. 2008 Mar 1
147 17962201 Thyroid function test abnormalities in patients with metastatic renal cell carcinoma treated with sorafenib. 2008 Feb 1
148 18082353 Sunitinib in the management of gastrointestinal stromal tumours (GISTs). 2008 Aug 4
149 18347007 Phase II study of sunitinib malate, an oral multitargeted tyrosine kinase inhibitor, in patients with metastatic breast cancer previously treated with an anthracycline and a taxane. 2008 Apr 10 2
150 18474019 New anti-angiogenic targeted therapy in advanced renal cell carcinoma (RCC): current status and future prospects. 2008 May 2